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Oxygen treatment for severe asthma could save lives
July 11, 2001Asthmatic patients are still dying during severe attacks, yet making oxygen available in every general practice to treat patients with a life threatening asthma attack could save lives, concludes a study in this week's BMJ. The authors urge the British Thoracic Society to review this issue when it updates its asthma guidelines.
A research team in London reviewed 11 studies of acute severe asthma in both children and adults. Despite some limitations, these studies show that hypoxaemia (an inadequate supply of oxygen to the tissues) is an important cause of death during a severe asthma attack. Some studies also suggest that treatment with air during severe attacks may worsen hypoxaemia.
The British Thoracic Society's guidelines advise oxygen as a first line treatment in hospital for all patients with acute severe asthma. In general practice however, the guidelines imply that general practitioners should be prepared to treat acute asthma of all severities but do not advise the use of oxygen for children or insist on its use in adults. This may be because many general practices do not keep an oxygen cylinder.
Oxygen should be the first treatment for acute severe asthma wherever the patient happens to be, say the authors. Given that most asthma deaths occur in the community, oxygen should be available in every general practice. Patients with severe disease could also be provided with oxygen cylinders for emergency use at home, they conclude.
British Medical Journal (BMJ)
Oxygen should be the first treatment for acute severe asthma wherever the patient happens to be, say the authors. Given that most asthma deaths occur in the community, oxygen should be available in every general practice. Patients with severe disease could also be provided with oxygen cylinders for emergency use at home, they conclude.
British Medical Journal (BMJ)
Asthma Current Events and Asthma News RSSExposures to metals and diesel emissions in air linked to respiratory symptoms in children
Exposure shortly after birth to ambient metals from residential heating oil combustion and particles from diesel emissions are associated with respiratory symptoms in young inner city children.
Exposure to both traffic, indoor pollutants puts some kids at higher risk for asthma later
New research presents strong evidence that the "synergistic" effect of early-life exposure to both outdoor traffic-related pollution and indoor endotoxin causes more harm to developing lungs than one or the other exposure alone.
Johns Hopkins researchers track down protein responsible for chronic rhinosinusitis with polyps
A protein known to stimulate blood vessel growth has now been found to be responsible for the cell overgrowth in the development of polyps that characterize one of the most severe forms of sinusitis, a study by Johns Hopkins researchers suggests.
Ancestry attracts, but love is blind
People preferentially marry those with similar ancestry, but their decisions are not necessarily based on hair, eye or skin colour.
Common plastics chemicals linked to ADHD symptoms
Phthalates are important components of many consumer products, including toys, cleaning materials, plastics, and personal care items.
Asthma a significant risk factor for complications in children with H1N1
A new study on pediatric H1N1 influenza admissions has found that asthma is a significant risk factor for severe disease in children with pandemic H1N1 compared with the seasonal flu.
Mother's Depression a Risk Factor in Childhood Asthma Symptoms, Study Suggests
Asthma symptoms can worsen in children with depressed mothers, according to research from Johns Hopkins Children's Center published online in the Journal of Pediatric Psychology.
Sweet -- sugared polymer a new weapon against allergies and asthma
Scientists at Johns Hopkins and their colleagues have developed sugar-coated polymer strands that selectively kill off cells involved in triggering aggressive allergy and asthma attacks.
Pivotal study for PSD502 -- the first potential treatment for premature ejaculation
At the annual meeting of the Sexual Medicine Society of North America (SMSNA), Inc. in San Diego, Sciele Pharma, Inc., a Shionogi Company and Plethora Solutions Limited, a wholly owned subsidiary of Plethora Solutions Holdings PLC ("Plethora" - AIM:PLE)., today presented data from its second positive pivotal study of PSD502 for the treatment of premature ejaculation (PE).
Aileron collaborates study in Nature: Stapled peptides inhibit Notch1 transcription factor
This research validates the potential for Stapled Peptides to modulate key intracellular biological targets, such as transcription factors, that have not been addressable with current small molecule or biologic drug modalities.
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