Invasive procedures still performed on conscious children despite new anaesthetic techniquesJune 19, 2001Many invasive bone marrow procedures are still carried out in conscious children despite the safety and effectiveness of modern anaesthetic and deep sedation techniques, finds a study in Archives of Disease in Childhood. The findings also show a striking difference between the North American and European approaches to managing painful procedures in children with cancer. The research team surveyed 118 children's cancer centres in North America and Europe about their approaches towards managing painful procedures. They found that North American centres tended to use less effective techniques than European, especially for bone marrow procedures. Furthermore, a much larger proportion of centres in North America reported still performing these procedures on conscious patients. Nearly one third of centres used neither general anaesthetic nor deep sedation for the majority of bone marrow procedures. Over a quarter of North American centres, but no European ones, reported using nothing or topical anaesthetic alone. A move away from performing bone marrow procedures on conscious patients has long been anticipated, but appears to be happening slowly, say the authors. The reason for this reluctance is unclear, but it may reflect a misperception that the risks of adverse effects are high, or be related to practical difficulties in obtaining anaesthetic support, they conclude. British Medical Journal (BMJ) |
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| Related Bone Marrow Current Events and Bone Marrow News Articles Gene mismatch influences success of bone marrow transplants A commonly inherited gene deletion can increase the likelihood of immune complications following bone marrow transplantation, an international team of researchers reports in the November 22 advance online issue of Nature Genetics. New cancer target for non-Hodgkin's lymphoma Physician-scientists from Weill Cornell Medical College have discovered a molecular mechanism that may prove to be a powerful target for the treatment of non-Hodgkin's lymphoma, a type of cancer that affects lymphocytes, or white blood cells. Bone Implant Offers Hope for Skull Deformities A synthetic bone matrix offers hope for babies born with craniosynostosis, a condition that causes the plates in the skull to fuse too soon. U of M researchers find 2 units of umbilical cord blood reduce risk of leukemia recurrence A new study from the Masonic Cancer Center, University of Minnesota shows that patients who have acute leukemia and are transplanted with two units of umbilical cord blood (UCB) have significantly reduced risk of the disease returning. Scientists successfully reprogram blood cells Researchers have transplanted genetically modified hematopoietic stem cells into mice so that their developing red blood cells produce a critical lysosomal enzyme -preventing or reducing organ and central nervous system damage from the often-fatal genetic disorder Hurler's syndrome. Immune therapy can protect against or treat later lymphoma Specially developed immune system cells that target the common Epstein-Barr virus can protect immune-suppressed bone marrow transplant recipients against lymph system disease and cancers that arise from the viral infection. Stem cell therapy may offer hope for acute lung injury Researchers at the University of Illinois at Chicago College of Medicine have shown that adult stem cells from bone marrow can prevent acute lung injury in a mouse model of the disease. New insight in the fight against the Leishmania parasite Professor Albert Descoteaux's team at Centre INRS - Institut Armand-Frappier has gained a better understanding of how the Leishmania donovani parasite manages to outsmart the human immune system and proliferate with impunity, causing visceral leishmaniasis, a chronic infection that is potentially fatal if left untreated. 2-million-year-old evidence shows tool-making hominins inhabited grassland environments In an article published in the open-access, peer-reviewed journal PLoS ONE on October 21, 2009, Dr Thomas Plummer of Queens College at the City University of New York, Dr Richard Potts of the Smithsonian Institution National Museum of Natural History and colleagues report the oldest archeological evidence of early human activities in a grassland environment, dating to 2 million years ago. Mice regain ability to extend telomeres suggesting potential for dyskeratosis congenita therapy The human genetic disease dyskeratosis congenita (DKC) is an autosomal dominant disease that leads to abnormalities in tissues with a rapid cell turnover - the skin, nails, bone marrow, lungs and gut. More Bone Marrow Current Events and Bone Marrow News Articles |
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