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Dietary fat itself not likely to cause breast cancer
October 16, 2000A diet high in fat is not by itself likely to cause breast cancer, suggests a study in the Journal of Epidemiology and Community Health. But it is likely to deplete the body of an essential nutrient, a factor that is probably responsible for most cases of the disease, concludes the research.
The author examined all the relevant epidemiological and biological data in support of current evidence about breast cancer, the main cause of which is still unknown. Other factors, such as obesity, first motherhood over the age of 30, childlessness, and radiation, account for only a small proportion of cases, and are probably secondary to the factors that determine risk, he says.
Genes are not the answer, because there is a low prevalence of family history and women with similar genetic profiles develop the disease at different rates when they move to other countries. The data do not incriminate pollution or infection as the causes. While oestrogen is implicated in the development of the disease, the published evidence points to its promoter rather than causal role. But there is evidence for dietary factors, especially fat, says the author.
Although a causative factor is yet to be identified, the hypothesis that best fits the epidemiological data, concludes the author, is that dietary fat depletes breast tissue of an essential factor that normally protects against the development of the disease. This works in tandem with age and the effects of oestrogen.
campuspr
Breast Cancer Current Events and Breast Cancer News RSSClue to genetic cause of fatal birth defect
A novel enzyme may play a major role in anencephaly, offering hope for a genetic test or even therapy for the rare fatal birth defect in which the brain fails to develop, according to a study from researchers at the University of Illinois at Chicago College of Medicine.
Bisphenol A linked to chemotherapy resistance
Exposure to bisphenol A (BPA) may reduce the effectiveness of chemotherapy treatments, say University of Cincinnati (UC) scientists.
Tamoxifen chemoprevention tied to early detection of breast cancer
The drug tamoxifen does not prevent or treat estrogen receptor (ER) negative breast cancer, but it can make the disease easier to find, researchers report in the Oct. 1 Journal of the National Cancer Institute.
Herbal Menopause Therapy a Good Fit for Breast Cancer Patients?
When it comes to understanding the effectiveness and safety of using herbal therapies with other drugs, much is unknown. Now, a University of Missouri researcher will study how black cohosh - an herbal supplement often used to relieve hot flashes in menopausal women - interacts with tamoxifen, a common drug used to treat breast cancer.
Genetic Engineering & Biotechnology News reports on growing role of molecular diagnostics
Novel platform technologies and key advances in genomics are rapidly driving the development of molecular diagnostics, reports Genetic Engineering and Biotechnology News (GEN).
Study looks at psychological impact of gene test for breast cancer
Personal beliefs about inconclusive DNA testing for hereditary breast cancer are associated with cancer-related worry, and such beliefs are an especially strong predictor of whether women had been able to leave the period of DNA-testing behind.
Second lumpectomy for breast cancer reduces survival rates
A majority of women with breast cancer today are candidates for lumpectomy, allowing for conservation of most of their breast tissue.
MRI spots DCIS in mice
A new magnetic resonance imaging procedure can detect very early breast cancer in mice, including ductal carcinoma in situ (DCIS), a precursor to invasive cancer. Some of the tumors detected were less than 300 microns in diameter, the smallest cancers ever detected by MRI.
Birth size is a marker of susceptibility to breast cancer later in life
Birth size, and in particular birth length, correlates with subsequent risk of breast cancer in adulthood, according to a new study published in PLoS Medicine by researchers at the London School of Hygiene and Tropical Medicine.
Social class dictates cancer risk
Cervical and lung cancer are more common in poor people while rates of breast cancer and melanoma are higher in the wealthy.
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