RSS Feeds

Earth Science

Space Science

Life Science

Fields of Scientific Study

Nanotechnology

Cancer

Definitions of The Fields of Scientific Study

Southampton study aims to pinpoint heart disease genes

May 26, 1999

REF: 99/53
15 APRIL 1999

Southampton experts, funded by the British Heart Foundation, are to research genetic influences on coronary heart disease as part of a major new project, The Southampton Atherosclerosis Study.

Patients at Southampton General Hospital receiving heart examinations carried out using angiography--which reveals the presence of lesions in the arteries that supply blood to the heart--will be asked to participate in the study.

Volunteers will then be anonymously 'genotyped' to see whether a correlation can be drawn between variants of a certain gene (or combination of genes) and the severity of heart disease.

'It has been known for a long time that environmental factors, such as a high-fat diet and smoking, contribute to heart disease,' explains project leader Dr Shu Ye, of the University's Department of Human Genetics. 'However there are also a number of different genes which we believe may influence susceptibility and severity of heart disease.

'The Southampton Atherosclerosis Study will help us to gain a better understanding of the mechanisms which contribute to
heart disease. The results could also provide opportunities to identify high-risk individuals, and lead to the development of new preventative and therapeutic measures.'

Southampton, University of

Related Atherosclerosis Current Events and Atherosclerosis News Articles

Atherosclerosis Current Events and Atherosclerosis News RSS

Vitamin B niacin offers no extra benefit to statin therapy in seniors already diagnosed with CAD
The routine prescription of extended-release niacin, a B vitamin (1,500 milligrams daily), in combination with traditional cholesterol-lowering therapy offers no extra benefit in correcting arterial narrowing and diminishing plaque buildup in seniors who already have coronary artery disease, a new vascular imaging study from Johns Hopkins experts shows.

Early end to key study on benefits of niacin, a B vitamin, in keeping arteries open was premature
Heart experts at Johns Hopkins are calling premature the early halt of a study by researchers at Walter Reed Army Medical Center and Washington Hospital Center on the benefits of combining extended-release niacin, a B vitamin, with cholesterol-lowering statin medications to prevent blood vessel narrowing.

Can charcoal fight heart disease in kidney patients?
Charcoal may provide a new approach to managing the high rate of heart disease in patients with advanced kidney disease, according to preliminary research being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA.

Experts unveil new CVD guidelines and position papers
Several new guidelines and position papers offering the most up to date information to ensure that clinicians practice evidence-based medicine were released at the Canadian Cardiovascular Congress 2009 this week.

Canadian scientists link fat hormone to death from potentially deadly blood infection
A new Canadian study has found that lower-than-normal levels of a naturally-occurring fat hormone may increase the risk of death from sepsis-an overwhelming infection of the blood which claims thousands of lives each year.

Healthy neighborhoods may be associated with lower diabetes risk
Individuals living in neighborhoods conducive to physical activity and providing access to healthy foods may have a lower risk of developing type 2 diabetes in a five-year period, according to a report in the October 12 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Liver cells grown from patients' skin cells
Scientists at The Medical College of Wisconsin in Milwaukee have successfully produced liver cells from patients' skin cells opening the possibility of treating a wide range of diseases that affect liver function.

National report shines light on lupus 50-year treatment drought
Today, The Lewin Group, a national health care consulting firm, issued recommendations on ways to overcome the barriers that have obstructed lupus drug development resulting in no new drug approval for this disease in more than 50 years - since the Eisenhower Administration.

Calcium scans may be effective screening tool for heart disease
A simple, non-invasive test appears to be an effective screening tool for identifying patients with silent heart disease who are at risk for a heart attack or sudden death.

Despite size, NFL players not more likely to develop heart disease, even after retirement
Former professional football players with large bodies don't appear to have the same risk factors for heart disease as their non-athletic counterparts, UT Southwestern Medical Center researchers have found in studying a group of National Football League (NFL) alumni.

More Atherosclerosis Current Events and Atherosclerosis News Articles

	Dyslipidemia and Atherosclerosis Essentials 2009 by Christie M. Ballantyne (Author), James H. O'Keefe (Author), Antonio M. Gotto (Author) The World's Leading Experts Provide all the 'Essentials' Needed to Manage Patients in the Office, on the Ward, and in the Intensive Care Unit! Written by key opinion leaders in the field of cardiology, Dyslipidemia Essentials integrates the latest clinical guidelines and trials into a practical step-by-step guide to the management of dyslipidemia. Important clinical trials, common management pitfalls, and other cardiovascular risk reduction measures are also emphasized. Topics include: Step-by-step guide to intensive LDL lowering; NCEP ATP III and AHA/ACC guideline Updates; Treatment of low HDL cholesterol and elevated triglyceride; 73 dyslipidemia trials and 17 drug summaries
	Unclog Your Arteries : How I Beat Atherosclerosis by Gene McDougall (Author) Heart attack or bypass surgery? - or even if not- if you are overweight, have high blood pressure, high blood sugar, diabetes, high cholesterol, heart disease, or a family history of any, read this and then keep it for reference.
	Biochemistry of Atherosclerosis (Advances in Biochemistry in Health and Disease) by Sukhinder C. Kaur (Editor) At its present rate of growth, atherosclerosis will be the major cause of death from disease by the year 2020. Atherosclerosis is an extremely complex, biochemical, multifactorial process. This book will cover many aspects of atherogenesis, with particular emphasis on lipid and lipoprotein metabolism. We will cover all aspects of the regulation of cholesterol homeostasis and the importance of each pathway. This book will explore the role of nuclear hormone receptors on lipid and lipoprotein metabolism and their complex roles in atherogenesis. Finally, how the use of genetic studies can help sort out the immense complexities that mediate these aspects of atherogenesis will be discussed.
	Molecular Mechanisms of Atherosclerosis by Joseph Loscalzo (Editor) Atherosclerosis is the most common cardiovascular disorder in western societies and is rapidly becoming similarly prevalent in the underdeveloped world. Written by notable authorities and providing text rich in illustrative figures, Molecular Mechanisms in Atherosclerosis addresses the fundamental mechanisms underlying atherothrombosis and delineates current views of the molecular and cellular basis of the process. The editor approaches the issue from a mechanistic perspective, and does so in the context of contemporary knowledge of molecular and cellular pathobiology. The book provides an epidemiological overview of atherosclerotic vascular disease, followed by a review of the genetics and genetic epidemiology. It focuses on the four fundamental mechanisms common to all risk...
	Anatomical Artery Cholesterol Atherosclerosis - Progressively Clogged by GPI Cholesterol: 4-Stage cross section of an artery demonstrating arteriosclerosis in which the narrowing of the artery is due to a build up of fatty tissue (cholesterol) and plaque. 4-Stages: normal artery, fatty streak, fibrous plaque, and blockage. The stages cause a decrease in blood flow, which can lead to a blood clot or thrombus. All stages rotate on hinge pin. Suitable for Cardio-Vascular, Cardiology and Internal Medicine, general anatomical study, training for surgical dissection, or for patient education or demonstration of procedures. Quantity discounts available. Made of a durable, plastic material accurately designed and colored to represent the major structures and, in certain instances, lesions or other abnormalities as described above. We also have available the unique...
	Journal of Atherosclerosis and Thrombosis by Japan Publications Trading Co
	Lipids and Atherosclerosis (Advances in Translational Medical Science) by Chris J. Packard (Author), Daniel J. Rader (Author) New discoveries in genetics, molecular, and cell biology are not only enhancing our understanding of the etiology and progression of disease, but are finding applications in the development of new drugs or the implementation of new kinds of therapy. This book provides an in-depth review of emerging areas in biomedical research at the interface of science and clinical medicine. Written by a team of well-known experts, Lipidology: Translational Medical Science presents an authoritative overview of key advances in biomedical research and reviews the most important recent advances in lipidology, highlighting their relationship to cardiovascular disease.
	Nature Made Selenium Supplement Tablets, 200 mcg, 100-Count Bottles (Pack of 3) by Nature Made An antioxidant that complements Vitamin E to help protect cells from free radicals thought to be responsible for cellular damage. *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to
	Transeophageal Echo Aorta with Heavy Atherosclerosis Photographic Poster Print, 40x30 by AllPosters.com AllPosters.com is the world's #1 seller of posters, prints, photographs, specialty products and framed art. We're dedicated to bringing our customers the best selection of high quality wall décor that is perfect for their home or office. Browse our catalog of over 300,000 items that include entertainment and specialty posters, decorative prints, and art reproductions. Whether you're looking for your favorite movie or music poster, a framed Monet reproduction, or a print of the Eiffel Tower you will find it at AllPosters.com. Visit our Amazon store today at www.amazon.com/allposters to find Special Offers and search by subject category or artist. AllPosters.com provides unmatched service with a 100% satisfaction guarantee. We ship internationally to over 80 countries. Decorate your...
	The Nutritional Bypass : Reverse Atherosclerosis Without Surgery by David W. Rowland (Author) Did you know that there is a time tested, safe, non-surgical method of removing arterial blockages-without side effects? Severe arterial blockages do not have to lead to coronary bypass surgery or heart attacks. Inside this book is a complete program for successfully reversing and preventing hardening of the arteries. You may be surprised to know that cholesterol is not the cause of heart disease and that polyunsaturated oils may actually be doing more harm than good.