Brain imaging studies show attention to thinking in schizophrenia improves outlook for patientsMarch 16, 1999A focus on schizophrenia as 'a disorder of thinking' promises much for patients with the condition, according to Dr Tonmoy Sharma, Head of the Section of Cognitive Psychopharmacology (SCP) at the Institute of Psychiatry. In a presentation to journalists during Brain Awareness Week, Dr Sharma outlined new research showing the importance of cognitive problems in schizophrenia. 'We now recognise that problems in cognition - reduced attention span, problems with memory and difficulties in reasoning and problem solving - are core features of schizophrenia. Routine activities that we take for granted can be very difficult; even planning a simple shopping trip can be complex and demanding if our ability to make decisions is reduced. 'Improving cognition transforms a patient's ability to work and socialise. We want to find the best ways to achieve this transformation in people with schizophrenia.' In SCP, neuroimaging research has revealed differences in the function of the brains of people with schizophrenia compared with those without the illness. A new way of imaging the brain's activity - functional magnetic resonance imaging - was used to compare the activity of certain brain regions during cognitive tasks. Ongoing research in SCP is also employing functional magnetic resonance imaging to study the effects of some antipsychotic drugs, which have been shown to improve cognition in schizophrenia. By imaging the brains of patients who are taking these drugs, researchers are hoping to find out more about how cognitive abilities increase with medication. Dr Sharma believes that improving cognition is an important therapeutic goal in schizophrenia. Institute of Psychiatry |
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