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STUDY OF QUAKING STARS WINS RAS PRIZE
November 06, 1998page 1 of 2
For immediate release - 2 November 1998
ALZHEIMER'S IN THE 'NEWS'
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The fourth most common cause of death in the Western world is Alzheimer's, a disease which is also the single most common cause of dementia - a general decline in all areas of mental ability. A report published today by the Wellcome Trust (Research directions in Alzheimer's disease), reviews a range of research projects which aim to provide vital clues towards developing new diagnosis and treatments for this tragic disease.
At present, no one test can accurately diagnose Alzheimer's and there are no effective treatments to reverse the memory loss associated with the disease. Research Directions highlights advances in understanding a variety of aspects of Alzheimer's, from memory loss and co-ordination, to the patient's relationship with their carer. These include:
A Wellcome Cup of Tea (page 27)
By analysing a video archive of over 800 tea-making attempts of nine people with probable Alzheimer's, Dr Jennifer Rusted at Sussex University has discovered that patients have a greater capacity to recall routine behaviour than expected. Even in advanced stages of the disease, they complete the task by using flexible and thoughtful strategies, not automated actions.
Counting ladybirds (page 25)
An ingenious computer based 'game' could result in a non-invasive test to diagnose and monitor Alzheimer's disease. Professor Sergio Della Sala and colleagues at the University of Aberdeen, have devised this test by focusing on what they believe to be a unique and early symptom of Alzheimer's disease, a failure in dual task co-ordination.
Caring for the carers (page 28)
A good relationship with their carer results in a happy life for the Alzheimer's patient but a carer suffering from stress creates a hostile environment. By assessing the behaviours of 100 Alzheimer's patients and their carers, Professor Alistair Burns and colleagues at the University of
page 2 of 2
Manchester have discovered that education about dementia is the key to helping carers avoid stress. This will not only aid existing medical treatments but help reduce the burden on resources such as home and respite care.
Noorece Ahmed/Catherine Nestor
Press Office
The Wellcome Trust
Tel: 0171 611 8540 / 8846
Fax: 0171 611 8416
email: press.office@wellcome.ac.uk
Wellcome Trust, The
At present, no one test can accurately diagnose Alzheimer's and there are no effective treatments to reverse the memory loss associated with the disease. Research Directions highlights advances in understanding a variety of aspects of Alzheimer's, from memory loss and co-ordination, to the patient's relationship with their carer. These include:
A Wellcome Cup of Tea (page 27)
By analysing a video archive of over 800 tea-making attempts of nine people with probable Alzheimer's, Dr Jennifer Rusted at Sussex University has discovered that patients have a greater capacity to recall routine behaviour than expected. Even in advanced stages of the disease, they complete the task by using flexible and thoughtful strategies, not automated actions.
Counting ladybirds (page 25)
An ingenious computer based 'game' could result in a non-invasive test to diagnose and monitor Alzheimer's disease. Professor Sergio Della Sala and colleagues at the University of Aberdeen, have devised this test by focusing on what they believe to be a unique and early symptom of Alzheimer's disease, a failure in dual task co-ordination.
Caring for the carers (page 28)
A good relationship with their carer results in a happy life for the Alzheimer's patient but a carer suffering from stress creates a hostile environment. By assessing the behaviours of 100 Alzheimer's patients and their carers, Professor Alistair Burns and colleagues at the University of
page 2 of 2
Manchester have discovered that education about dementia is the key to helping carers avoid stress. This will not only aid existing medical treatments but help reduce the burden on resources such as home and respite care.
Noorece Ahmed/Catherine Nestor
Press Office
The Wellcome Trust
Tel: 0171 611 8540 / 8846
Fax: 0171 611 8416
email: press.office@wellcome.ac.uk
Wellcome Trust, The
Alzheimer Disease Current Events and Alzheimer Disease News RSSDelirium in hospitalized adults: Situation critical, no relief available
Every year as many as seven million adults in the United States experience delirium during hospitalization.
New data demonstrate potential for early detection of Alzheimer's disease
Data published in the June issue of the Journal of Alzheimer's Disease demonstrated that minimally-invasive biospectroscopy was able to identify changes in oxidative stress (OS) levels in blood plasma, which may prove to be a useful biomarker in the early detection of Alzheimer's disease.
Another McGill/JGH breakthrough opens door to early Alzheimer's diagnosis
A new diagnostic technique which may greatly simplify the detection of Alzheimer's disease has been discovered by researchers at McGill University and the affiliated Lady Davis Institute for Medical Research at Montreal's Jewish General Hospital (JGH).
Measuring brain atrophy in patients with mild cognitive impairment
Scientists at the University of California, San Diego School of Medicine have shown that a fully automated procedure called Volumetric MRI - which measures the "memory centers" of the brain and compares them to expected size - is effective in predicting the progression from mild cognitive impairment (MCI) to Alzheimer's disease.
Commonly used medications may produce cognitive impairment in older adults
Many drugs commonly prescribed to older adults for a variety of common medical conditions including allergies, hypertension, asthma, and cardiovascular disease appear to negatively affect the aging brain causing immediate but possibly reversible cognitive impairment, including delirium, in older adults.
Commonly used ulcer drugs may offer treatment potential in Alzheimer's disease
In a new study, published in the May issue of Elsevier's Experimental Neurology, scientists at the University of British Columbia have discovered that drugs commonly used to treat ulcers have significant neuroprotective properties, which appear to be enhanced when used in combination with ibuprofen, a widely used anti-inflammatory drug.
New test for mysterious metabolic diseases developed at Stanford/Packard
Scientists at Stanford University School of Medicine have devised a much-needed way to monitor and find treatments for a mysterious and devastating group of metabolic diseases that arise from mutations in cells' fuel-burning mechanism.
Recalibrating 'fight or flight'
A Canadian/U.S. research team has reported a novel approach to stimulating recovery from chronic stress disorders. Details of the therapeutic model, which exploits the natural dynamics of the body's "fight or flight" system, are published January 23 in the open-access journal PLoS Computational Biology
Vitamin B does not slow cognitive decline in Alzheimer's
A clinical trial led by Paul S. Aisen, M.D., professor of neurosciences at the University of California, San Diego School of Medicine, showed that high-dose vitamin B supplements did not slow the rate of cognitive decline in patients with mild to moderate Alzheimer disease.
Protecting patient privacy the new fashioned way
Protecting patient privacy has been recognized as the duty of health-care providers for about as long as doctors have seen patients. In 1996 that duty became a legal obligation when Congress passed the Health Insurance Portability and Accountability Act.
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