Study finds multiple markers for breast and ovarian cancerAugust 01, 2005Simple blood test may give diagnostic and prognostic information Scientists from the Uppsala Branch of the Ludwig Institute for Cancer Research (LICR) have made a promising discovery that could improve the early diagnosis of breast and ovarian cancers through a simple blood test. The LICR team, working in collaboration with a group at the Lviv Regional Oncology Center in Ukraine, discovered three proteins present in the blood of women with breast and ovarian cancer, but not in the blood of women without cancer, according to a study published today in the International Journal of Cancer. "Attempts to find a single reliable early protein, or 'marker', for breast or ovarian cancer diagnosis have not been very successful," says LICR's Dr. Serhiy Souchelnytskyi, the senior author of the study. "However, the use of multiple markers clearly improves the diagnostic ability. There are indications that these markers may also one day be useful for prognosis of the disease course. The proteomics-based discoveries of combinations of markers are already stimulating the development of tests for monitoring the appearance and progression of cancer." According to Dr. Kunle Odunsi from the Roswell Park Cancer Institute in the USA, head of the international Cancer Vaccine Collaborative's Ovarian Cancer Initiative, a discovery such as this greatly improves the potential for predictive tests and thus the long-term outlook for patients. "Early detection is crucial for effective treatment, particularly for ovarian cancer. If we can use a simple blood screen to identify this cancer at a very early stage, we can almost certainly make a positive impact on patient health and survival." Ludwig Institute for Cancer Research |
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| Related Ovarian Cancer Current Events and Ovarian Cancer News Articles FDA approved leukemia drugs shows promise in ovarian cancer cells The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA's Jonsson Comprehensive Cancer Center found. American Dietetic Association Releases Updated Position Paper Promoting and Supporting Breastfeeding The American Dietetic Association has released an updated position paper on breastfeeding that details health benefits for both infants and mothers and encourages promotion of breastfeeding whenever possible. Metals could forge new cancer drug Drugs made using unusual metals could form an effective treatment against colon and ovarian cancer, including cancerous cells that have developed immunity to other drugs, according to research at the University of Warwick and the University of Leeds. Breast cancer patients with high risk gene diagnosed 6 years earlier than generation before Women with a deleterious gene mutation are diagnosed with breast cancer six years earlier than relatives of the previous generation who also had the disease and/or ovarian cancer, according to new research from The University of Texas M. D. Anderson Cancer Center. Cancer Predisposition From Gene Variant Shows Strong Gender Bias Cancer predisposition resulting from the presence of a specific gene variant shows a strong gender bias, researchers at the University of Cincinnati (UC) have demonstrated. Medications Effective in Reducing Risks for Breast Cancer Can Also Cause Serious Side Effects Three drugs that reduce a woman's chance of getting breast cancer also have been shown to cause adverse effects, according to a new report from the Agency for Healthcare Research and Quality (AHRQ), U.S. Department of Health & Human Services. Scientists from University of Hawaii at Manoa find genetic marker A new genetic marker associated with ovarian cancer risk was recently discovered by an international research group, led by scientists from the Cancer Research Genetic Epidemiology Unit in the United Kingdom. New treatment in sight for ovarian cancer In the future, women with metastatic ovarian cancer could be treated with a radioactive substance that can seek and destroy tumour cells. Young early stage ovarian cancer patients can preserve fertility A new study finds that young women with early-stage ovarian cancer can preserve future fertility by keeping at least one ovary or the uterus without increasing the risk of dying from the disease. Estrogen-Dependent Switch Tempers Killing Activity of Immune Cells The sex hormone estrogen tempers the killing activity of a specific group of immune cells, the cytotoxic T cells (CTLs), which are known to attack tumor cells and cells infected by viruses. More Ovarian Cancer Current Events and Ovarian Cancer News Articles |
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