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MDCT Arthrography Good for Assessing Hip Dysplasia
August 08, 2005MDCT arthrography is an accurate method for assessing cartilage loss in patients with hip dysplasia and may be more reliable than MRI in such instances, says a new study by researchers from Osaka University Medical School in Japan.
Hip dysplasia is a malformation or alteration of the ball (femur head) and socket (acetabulum) joint bones of the hip that can wear away the surrounding cartilage, which can lead to arthritis and other problems. "The condition is often caused by a birth defect or incomplete growth of the skeleton during childhood; women and those with a family history are the most at risk. In addition, reports have shown that 10 to 20% of Japanese people develop hip dysplasia, which is two to five times more than Caucasian people," said Takashi Nishii, MD, lead author of the study.
For the study, 18 patients with hip dysplasia underwent both MDCT arthrography and 3D spoiled gradient-echo MRI. The researchers found that MDCT arthrography had higher sensitivity (70-79%), specificity (93-94%) and accuracy (87-90%) rates than MRI (47-53%, 87-92% and 78-80%, respectively) in diagnosing cartilage loss.
According to the researchers, the advantages of MDCT arthrography over other methods of diagnosis such as X-ray and MRI include better 3D evaluation, higher resolution, higher signal-to-noise ratio, and better tissue contrast.
Detection of cartilage problems of any severity is important, say the researchers. "A high incidence of cartilage abnormalities in patients with hip dysplasia indicates the need for more sensitive imaging methods than those previously used. Our study suggests that MDCT arthrography may become a prominent method for imaging patients with hip dysplasia, including precise assessment of osteoarthritis progression, adequate planning of surgery, and accurate monitoring of the effects of drug treatment and surgery," said Dr. Nishii.
The study appears in the August 2005 issue of the American Journal of Roentgenology.
American Roentgen Ray Society
According to the researchers, the advantages of MDCT arthrography over other methods of diagnosis such as X-ray and MRI include better 3D evaluation, higher resolution, higher signal-to-noise ratio, and better tissue contrast.
Detection of cartilage problems of any severity is important, say the researchers. "A high incidence of cartilage abnormalities in patients with hip dysplasia indicates the need for more sensitive imaging methods than those previously used. Our study suggests that MDCT arthrography may become a prominent method for imaging patients with hip dysplasia, including precise assessment of osteoarthritis progression, adequate planning of surgery, and accurate monitoring of the effects of drug treatment and surgery," said Dr. Nishii.
The study appears in the August 2005 issue of the American Journal of Roentgenology.
American Roentgen Ray Society
Infants should be screened for hip trouble
Developmental hip dysplasia is the most common congenital defect in newborns. The condition occurs when a hip joint is shallow, unstable or when the joint is dislocated. Infants with the condition are often at risk of developing arthritis of the hip as a young adult.
Dog genome sequence and analysis published in Nature
An international research team led by scientists at the Broad Institute of MIT and Harvard announced today the completion of a high-quality genome sequence of the domestic dog, together with a catalog of 2.5 million specific genetic differences across several dog breeds.
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