 |
|
Incidence of nonmelanoma skin cancer on the rise among young adults
August 10, 2005A new study from Minnesota finds the incidence of nonmelanoma skin cancer increasing among men and women under the age of 40, according to an article in the August 10 issue of JAMA.
The overall incidence of nonmelanoma skin cancer, consisting of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), is increasing, according to background information in the article. This increasing incidence is most likely due to a combination of factors, including increased exposure to UV light, ozone depletion, and increased surveillance. Long-term exposure to the sun resulting in photodamage is perhaps the biggest risk factor for nonmelanoma skin cancer. In the United States, approximately 800,000 new cases of BCC and 200,000 new cases of SCC were diagnosed in 2000. Nonmelanoma skin cancer generally occurs in persons older than 50 years, and in this age group, its incidence is increasing rapidly. However, little is known about its incidence in persons younger than 40 years.
Leslie J. Christenson, M.D., of Mayo Clinic, Rochester, Minn., and colleagues conducted a study to estimate the sex- and age-specific incidence of BCC and SCC in Olmsted County, Minnesota, in a young population (less than 40 years old) from the beginning of 1976 through 2003. The patients in this study have comprehensive medical records captured through the Rochester Epidemiology Project.
During the study period, 451 incident basal cell carcinomas were diagnosed in 417 patients, and 70 incident squamous cell carcinomas were diagnosed in 68 patients. Overall, the age-adjusted incidence of basal cell carcinoma per 100,000 persons was 25.9 for women and 20.9 for men. The incidence of basal cell carcinoma increased significantly during the study period among women but not among men. Nodular basal cell carcinoma was the most common histologic subtype; 43.0 percent of tumors were solely nodular basal cell carcinoma and 11.0 percent had a mixed composition, including the nodular subtype. The incidence of squamous cell carcinoma was similar in men and women, with an average age- and sex-adjusted incidence of 3.9 per 100,000 persons; the incidence of squamous cell carcinoma increased significantly over the study period among both women and men.
Comparing the change in incidence rates for basal cell carcinoma, per 100,000 persons the rate for 1976-1979 for women was 13.4; for men, 22.9, and for both sexes, 18.2. For 2000-2003, the rate for women was 31.6; for men, 26.7; and for both sexes, 29.1.
For squamous cell carcinoma, per 100,000 persons the rate for 1976-1979 for women was 0.6; for men, 1.3, and for both sexes, 0.9. For 2000-2003, the rate for women was 4.1; for men, 4.2; and for both sexes, 4.1.
"This increase [in nonmelanoma skin cancer in young adults] may lead to an exponential increase in the overall occurrence of nonmelanoma skin cancer over time as the population ages. This may mean even greater demands for health care related to nonmelanoma skin cancer. Our results also emphasize the need to focus on the prevention of skin cancer in the very young so that the increasing incidence of a potentially preventable cancer can be halted," the authors conclude.
JAMA and Archives Journals
During the study period, 451 incident basal cell carcinomas were diagnosed in 417 patients, and 70 incident squamous cell carcinomas were diagnosed in 68 patients. Overall, the age-adjusted incidence of basal cell carcinoma per 100,000 persons was 25.9 for women and 20.9 for men. The incidence of basal cell carcinoma increased significantly during the study period among women but not among men. Nodular basal cell carcinoma was the most common histologic subtype; 43.0 percent of tumors were solely nodular basal cell carcinoma and 11.0 percent had a mixed composition, including the nodular subtype. The incidence of squamous cell carcinoma was similar in men and women, with an average age- and sex-adjusted incidence of 3.9 per 100,000 persons; the incidence of squamous cell carcinoma increased significantly over the study period among both women and men.
Comparing the change in incidence rates for basal cell carcinoma, per 100,000 persons the rate for 1976-1979 for women was 13.4; for men, 22.9, and for both sexes, 18.2. For 2000-2003, the rate for women was 31.6; for men, 26.7; and for both sexes, 29.1.
For squamous cell carcinoma, per 100,000 persons the rate for 1976-1979 for women was 0.6; for men, 1.3, and for both sexes, 0.9. For 2000-2003, the rate for women was 4.1; for men, 4.2; and for both sexes, 4.1.
"This increase [in nonmelanoma skin cancer in young adults] may lead to an exponential increase in the overall occurrence of nonmelanoma skin cancer over time as the population ages. This may mean even greater demands for health care related to nonmelanoma skin cancer. Our results also emphasize the need to focus on the prevention of skin cancer in the very young so that the increasing incidence of a potentially preventable cancer can be halted," the authors conclude.
JAMA and Archives Journals
Skin Cancer Current Events and Skin Cancer News RSSNew breast imaging technology targets hard-to-detect cancers
Breast-specific gamma imaging (BSGI) is effective in the detection of cancers not found on mammograms or by clinical exam, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).
Lung airway cells activate vitamin D and increase immune response
Vitamin D is essential to good health but needs to be activated to function properly in the human body. Until recently, this activation was thought to happen primarily in the kidneys, but a new University of Iowa study finds that the activation step can also occur in lung airway cells.
Chronic inflammation can help nurture skin cancer, study shows
Inflammation, a frontline defense against infection or disease, can help nurture skin cancer, researchers have found.
Children with cystic fibrosis not well covered by guidelines for vitamin D needs
Existing recommendations for treating vitamin D deficiency in children with cystic fibrosis (CF) are too low to cover the serious need, leaving most at high risk for bone loss and rickets, according to researchers at Johns Hopkins Children's Center.
2008 ozone hole larger than last year
The 2008 ozone hole - a thinning in the ozone layer over Antarctica - is larger both in size and ozone loss than 2007 but is not as large as 2006.
Pitt research indicates new virus is culprit, not bystander, in deadly skin cancer
University of Pittsburgh scientists are uncovering more evidence that a virus they recently discovered is the cause of Merkel cell carcinoma, an aggressive and deadly form of skin cancer.
Variant of vitamin D receptor gene linked to melanoma risk
A new analysis indicates an association between a gene involved in vitamin D metabolism and skin cancer. Published in the November 1, 2008 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study suggests that individuals with certain variants in a vitamin D-related gene, called BsmI, may be at an increased risk of developing melanoma.
History of nonmelanoma skin cancer is associated with increased risk for subsequent malignancies
Individuals with a history of nonmelanoma skin cancer (NMSC) are at increased risk for other cancers, according to a study published in the August 26 online issue of the Journal of the National Cancer Institute.
Researchers discover how rheumatoid arthritis causes bone loss
Researchers have discovered key details of how rheumatoid arthritis (RA) destroys bone, according to a study published in the Aug. 22 edition of the Journal of Biological Chemistry.
Researchers discover scent of skin cancer
According to new research from the Monell Center, odors from skin can be used to identify basal cell carcinoma, the most common form of skin cancer. The findings, presented at the 236th meeting of the American Chemical Society, may open doors to development of new methods to detect basal cell carcinoma and other forms of skin cancer.
More Skin Cancer Current Events and Skin Cancer News Articles
 | The Skin Cancer Answer: The Natural Treatment for Basal and Sqamous Cell Carcinomas and Keratoses by William I. Lane, Linda Comac A complete guide to the new vegetable-based skin cancer... |
 | Atlas of Skin Cancers Processed by Frozen Sections and Mohs Surgery by Stephen N. Snow This work is the first of its kind, demonstrating the interpretation of pathology slides processed by frozen sections. It includes clinical photos of the primary tumor of nearly every type of skin cancer, compiled from cases treated at the premier facility for Mohs micrographic surgery—the Dermatologic/Mohs Surgery Clinic at the University of Wisconsin School of Medicine and Public Health.... |
| Coping With Melanoma and Other Skin Cancers (Coping) by Wendy Long | |
 | Skin Cancer by Keyvan Nouri The ultimate all-in-one guide to diagnosing and treating skin cancer . . "This all-inclusive textbook contains the most comprehensive, up-to-date and detailed information on any topic related to skin cancer....It could serve as the main resource for any physician for years to come."--Perry Robins, MD, President, Skin Cancer Foundation (from the foreword). . Comprehensive in scope, yet precise... |
 | Avoiding Cancer One Day At A Time: Practical Advice For Preventing Cancer by Lynne Eldridge, David Borgeson The mortality rate from cancer hasn't changed in 60 years despite the billions invested to find a cure. Avoiding Cancer One Day At A Time provides solid, practical advice for preventing cancer by avoiding carcinogens and implementing lifestyle/dietary practices that modify cancer causing factors. Combining their experience in family medicine and epidemiology with their passion for disease... |
 | Skin Cancer (The Biology of Cancer) by Po-lin, Ph.d. So Skin cancer is the most common of all cancers; doctors detect it in about 1 million Americans every year. Skin Cancer examines this disease, which, if found early, is usually cured by relatively simple surgery. Readers will also gain valuable insight into how they can lower their risk for skin... |
 | 100 Questions & Answers about Melanoma & Other Skin Cancers by Edward F. McClay, Mary-Eileen T. McClay, Jodie Smith This book deals with skin cancer from a doctor's and a patient's... |
 | Cancer of the Skin: Text with CD-ROM by Darrell Rigel, Robert Friedman, Leonard M. Dzubow, Douglas Reintgen, Robin Marks, Jean-Claude Bystryn Cancer of the Skin offers a comprehensive overview of skin cancer from the underlying biology to the clinical features of the disease, diagnosis and therapy. The book has been created by a multi-disciplinary, international team of some of the world's leading experts on this important topic.Containing over 500 full color images, Cancer of the Skin focuses in particular on the importance of early... |
 | The Eggplant Cancer Cure: A Treatment for Skin Cancer and New Hope for Other Cancers from Nature's Pharmacy by Bill Cham Perfection or near-perfection is rare in any area of medicine. Dr. Bill Cham has achieved it in the treatment of two common cancers, basal cell carcinoma and squamous cell carcinoma. Dr. Cham's treatment also eliminates actinic keratosis, a usually benign (but potentially malignant) skin condition of middle ages and older. What's near-perfection? A treatment that: --Works nearly every time --Has... |
 | Skin Cancer: Recognition and Management by Robert A. Schwartz The second edition of Skin Cancer: Recognition and Management is a definitive clinical reference which comprehensively examines the wide range of premalignant and malignant cutaneous disorders, including melanoma, Kaposi's sarcoma and other sarcomas, cutaneous lymphoma, cutaneous metastatic disease and cutaneous markers of internal malignancy, with emphasis on the most recent advances in... |
| © 2008 BrightSurf.com |