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New research challenges assumptions about dementia incidence
August 23, 2005A new study on the incidence of dementia in England and Wales, published in the forthcoming issue of the open access journal PLoS Medicine, challenges three commonly held assumptions about dementia. Contrary to widespread views, the study found that there was no major difference in the incidence of dementia between men and women, that the incidence did not fall beyond a certain critical age, and that there was no difference in the incidence across five different sites (three urban and two rural).
Unlike many previous studies, restricted to single sites, this research, funded by the British Medical Research Council, applied a single methodological approach to over thirteen thousand people across five diverse sites. The researchers studied two thousand five hundred people from each site, dividing them into two age groups: those from sixty-five to seventy-four years of age; and those who were seventy-five years of age and older. Dementia incidence, or the number of new cases over a given time, rises with age. However, the study did not support the previous assumption that dementia incidence varied according to sex. The suggestion in the previous literature that incidence may fall again after a certain, critical age, was also not supported by the findings.
There was no convincing evidence of variation across the sites. This puts into question the idea that action to reduce cardiovascular disease will necessarily have an impact on dementia incidence: a proposal that emerged out of previous, single site studies with differing prevalence of cardiovascular disease and other chronic disorders. The results, together with the methodological approach developed for the Medical Research Council's study, will be valuable for the future research on dementia incidence that is needed to inform public health policy.
Public Library of Science
Public Library of Science
Dementia Current Events and Dementia News RSSStudy sheds light on causes of HIV dementia
A new study led by researchers at Albert Einstein College of Medicine of Yeshiva University has clarified how two major variants of HIV differ in their ability to cause neurologic complications.
M.I.N.D. Institute researchers call for fragile X testing throughout the lifespan
Writing in this week's Journal of the American Medical Association, UC Davis M.I.N.D. Institute researchers urge physicians to test for mutations of the fragile X gene in patients of all ages.
Bittersweet milestones
For many of the elderly, the golden years are anything but. Faced with health problems, financial issues and the death of a spouse or loved one, many adults 65 years and older suffer from depression. While research is emerging to help this group understand and treat the problem, another group - centenarians - has been left largely in the dark.
Rapid Screening Test Developed to Detect Early Alzheimer's Disease
With millions of baby boomers entering late adulthood, the number of patients with Alzheimer's disease (AD) is expected to drastically rise over the next several decades.
Caring for the caregiver: Redefining the definition of patient
One quarter of all family caregivers of Alzheimer's disease patients succumb to the stress of providing care to a loved one and become hospital patients themselves, according to an Indiana University study published in the November 2008 issue of the Journal of General Internal Medicine.
Vitamin B3 reduces Alzheimer's symptoms, lesions
An over-the-counter vitamin in high doses prevented memory loss in mice with Alzheimer's disease, and UC Irvine scientists now are conducting a clinical trial to determine its effect in humans.
Common epilepsy drug could prevent and treat Alzheimer's disease
The team led by UBC Psychiatry Prof. Weihong Song, who is also the Jack Brown and Family Professor and Chair in Alzheimer's Disease at UBC, found that if Valproic Acid (VPA) is used as a treatment in early stages of AD memory deficit is reversed.
Drinking alcohol associated with smaller brain volume
The more alcohol an individual drinks, the smaller his or her total brain volume, according to a report in the October issue of Archives of Neurology, one of the JAMA/Archives journals.
Has a new era of reinstitutionalization in mental health care begun?
A retrospective analysis of hospital episode statistics, involuntary admissions under the Mental Health Act 1983, and the number of psychiatric beds in England 1996-2006.
New study proves that pain is not a symptom of arthritis, pain causes arthritis
Pain is more than a symptom of osteoarthritis, it is an inherent and damaging part of the disease itself, according to a study published today in journal Arthritis and Rheumatism.
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