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Transplant rejection drug holds promise for inflammatory eye disease
September 02, 2005The immunosuppressive drug mycophenolate mofetil, used to prevent rejection of transplanted hearts, kidneys and livers, may also be effective in controlling inflammatory eye diseases, according to a study by researchers at Johns Hopkins' Wilmer Eye Institute.
"The drug seemed to be effective even in patients who had failed treatment from other immunosuppressive drugs," says lead author Jennifer E. Thorne, M.D., an assistant professor of ophthalmology.
Physicians gave the drug to 84 patients, of whom 61 percent had uveitis (intraocular inflammation), 17 percent had scleritis (inflammation of the outer wall of the eye), 11 percent had mucous membrane pemphigoid (a condition causing scarring of the eyelids) and 11 percent had inflammation behind the eye or in other areas. Patients took two pills each morning and two each evening, for a total dose of 2 grams daily. Thirty-six patients (43 percent) already had been treated with at least one other immunosuppressive drug.
Study results, published in the August issue of the journal Ophthalmology, showed that 81 patients (97 percent) had control of their ocular inflammation after one month of treatment. Eighty-two percent of patients had control of their inflammation and were able to taper their dose of the steroid prednisone to 10 or fewer milligrams daily.
Only seven patients discontinued the drug due to side effects such as stomach upset or mild diarrhea. In most cases, Thorne says, lowering the dose of medication can reduce side effects. The drug dosage often can then be increased without the side effects returning.
Johns Hopkins Medical Institutions
Study results, published in the August issue of the journal Ophthalmology, showed that 81 patients (97 percent) had control of their ocular inflammation after one month of treatment. Eighty-two percent of patients had control of their inflammation and were able to taper their dose of the steroid prednisone to 10 or fewer milligrams daily.
Only seven patients discontinued the drug due to side effects such as stomach upset or mild diarrhea. In most cases, Thorne says, lowering the dose of medication can reduce side effects. The drug dosage often can then be increased without the side effects returning.
Johns Hopkins Medical Institutions
Eye Disease Current Events and Eye Disease News RSSResearchers find new way to attack inflammation in Graves' eye disease
A small group of patients with severe Graves' eye disease experienced rapid improvement of their symptoms - and improved vision - following treatment with the drug rituximab.
Cataract surgery helps AMD patients; steroid improves DME; online eye health forum
This month's Ophthalmology, the journal of the American Academy of Ophthalmology (Academy) reports on a national study that finds cataract surgery is likely to benefit patients with age-related macular degeneration (AMD) at all stages of the disease, on a clinical trial showing that the steroid triamcinolone may be effective in advanced diabetic macular edema (DME) patients when standard treatment fails, and on the public's use of two Academy-sponsored online eye health forums.
Experimental treatments restore partial vision to blind people
Two experimental treatments, a retinal prosthesis and fetal tissue transplant, restored some vision to people with blinding eye diseases. The findings, presented at Neuroscience 2009, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news on brain science and health, may lead to new treatments for the blind.
Cancer drug is no different in effectiveness as gold standard treatment for macular degeneration
Investigators from Boston University School of Medicine (BUSM) and the VA Boston Healthcare System have shown, at 6 months in a small group of patients, that there is no difference in efficacy between Bevacizumab (Avastin) and Ranibizumab (Lucentis) for the treatment of age-related macular degeneration (AMD).
Toronto researchers discover novel circulation in human eye, new glaucoma treatment target
Researchers at the University of Toronto, St. Michael's Hospital and Sunnybrook Health Sciences Centre have discovered a previously unidentified form of circulation within the human eye which may provide important new insights into glaucoma, a leading cause of blindness.
International conference on endothelin
One of the most intriguing developments in recent medical science is the discovery of the human chemical endothelin (ET).
JDRF-funded studies show regular CGM use increases diabetes control for all age groups
The latest data from groundbreaking human clinical trials of the effectiveness of continuous glucose monitors (CGM) show that the primary determinant of improvements in achieving better diabetes control is regular use of monitors - six days per week or more - rather than the age of patients, and that benefits continue well past the time when people with type 1 diabetes begin using the devices - including experiencing fewer low blood sugar emergencies.
Elevated arginase levels contribute to vascular eye disease such as diabetic retinopathy
Elevated levels of the enzyme arginase contribute to vascular eye damage and Medical College of Georgia researchers say therapies to normalize its levels could halt progression of potentially blinding diseases such as diabetic retinopathy.
Anti-growth factor drugs raise hope and concern for treatment of children's eye diseases
A new class of antibody drugs may provide a powerful new tool for the treatment of eye diseases in children, but specialists need to be alert for the possibility of serious side effects, according to an editorial in the August Journal of AAPOS (American Association for Pediatric Ophthalmology and Strabismus), published by Elsevier.
Natural Compound Stops Diabetic Retinopathy
Researchers at the University of Oklahoma Health Sciences Center have found a way to use a natural compound to stop one of the leading causes of blindness in the United States.
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The Wills Eye Manual: Office and Emergency Room Diagnosis and Treatment of Eye Disease (Rhee, The Wills Eye Manual) by Justis P Ehlers (Editor), Chirag P Shah (Editor), Gregory L Fenton (Editor), Eliza N Hoskins (Editor), Heather N Shelsta (Editor) Now in full color and completely updated, the Fifth Edition of this best-selling manual is a reliable quick-reference guide for all clinicians who treat eye disorders. Every disorder encountered in the office, emergency room, or hospital is covered in concise outline format: symptoms, signs, work-up, treatment, and follow-up. Also included are chapters on differential diagnosis of ocular symptoms and signs, a section on current imaging modalities in ophthalmology, and a Pharmacopoeia. This edition features over 200 full-color photographs and includes the newest drugs, procedures, and treatment protocols. New topics covered include iridodialysis/cyclodialysis, shaken baby syndrome, crystalline keratopathy, refractive surgery complications, aberrant regeneration of the third nerve, venous... |
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Yoga for Eye Diseases [Swami Ramdev] |
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PetAlive Eye-Heal for Pet Eye Infections by PetAlive Causes of infections include various bacteria, viruses like the Herpes virus, foreign material or irritants in the eye and even Lyme disease. Common signs and symptoms of eye infection in pets include squinting of the eye, watery or mucoid discharge, red or swollen conjunctiva (the pink part just inside the eyelids), the iris (colored part of the eye) may also appear dull or cloudy. Conventional treatment usually involves aspirin, corticosteroids, or other anti-inflammatory drugs for pain relief - as well as eye drops or ointments and topical or oral antibiotics. PetAlive Eye-Heal contains a blend of pure and natural ingredients in an herbal tincture and will effectively treat and prevent eye infections in dogs and cats as well as improve general eye and visual health. |
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Balanceuticals Clear Eye & Sharp Ear Dietary Supplement Capsules, 500 mg, 60-Count Bottles (Pack of 2) by Balanceuticals Dietary Supplement. 100% Natural. Made under Supervision by China Academy of Traditional Chinese Medicine. Made of extracts from astragalus root, pueraria root, seashore vitex, common peony root, cimicifuge, phellodendron, licorice, cnidium, Chinese angel |
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Hearts&Minds No-Stir Peanut Butter with Olive Oil and Omega-3Crunchy, 11.3 Ounce Bottles (Pack of 6) by Hearts&Minds Hearts&Minds LLC creates great tasting products thoughtfully made with the consumer's heart in mind by using heart healthy olive oil and omega-3 (EPA/DHA) to replace a portion of the fat in foods consumers love. Hearts&Minds® peanut butter helps con |
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Please read this while I stare at your tits EYE EXAM CHART Logo Men's Hoodie Sweat Shirt Small thru 4XL by 99 Volts |
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Selling Your Disease (Alt. Mix) The Masked Musician (Primary Contributor) |
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Thyroid Eye Disease: Understanding Graves\' Ophthalmopathy by Elaine A. Moore (Author) The only educational resource and guide for patients with Graves' Ophthalmopathy, an inflammatory eye disorder that often precedes, accompanies, or follows autoimmune thyroid disease. |
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Unseen Ellis Island New York - ViewMaster 3 Reel Set by View-Master The first reel, Ellis Island Vintage Images, offers a view into early images of immigrants being processed for entry to America: * Immigrants' First View of Ellis Island * Hopeful Immigrants on Ship * Immigrants in Waiting Area * Brief but thorough Medical Exam * Inspector Checking for Trachoma Eye Disease * New Americans * Immigrants Settled in Lower Eastside NYC. The other 2 reels provide a look at Ellis Island few have ever seen. It's the South Side priori to stabilization and renovation. A unique glimpse. |
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