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Less invasive surgery effective in treatment of reflux disease
October 18, 2005CHICAGO - Laparoscopic (minimally invasive) surgery to treat severe reflux disease was effective in relieving symptoms and was associated with high rates of patient satisfaction five years after the procedure, according to a study in the October issue of Archives of Surgery, one of the JAMA/Archives journals.
Laparoscopic anti-reflux surgery has been gaining in popularity for the treatment of severe symptomatic gastroesophageal reflux disease (GERD), according to background information in the article. Few previous studies have reported five-year follow-up for a large group of patients who have undergone laparoscopic surgery to treat severe reflux disease.
Patrick Pessaux, M.D., of the University Hospital, Angers, France, and colleagues evaluated patients who had undergone one of three types of laparoscopic anti-reflux surgery in one of 31 hospital centers between January 1992 and December 1998. Outcome data covering five or more years was available for 1,340 patients, 815 men and 525 women (average age 49.3 years). The average follow-up was 7.1 years. Patients were evaluated post-operatively using a standardized questionnaire including questions on gastrointestinal symptoms and satisfaction with surgery.
"In this study, the intraoperative and postoperative complication rates were 2.1 percent and 2.6 percent, respectively, with a subsequent operation rate of 4.4 percent at five years," the researchers report. "Of interest, overall patient satisfaction following surgery was high, with 93.1 percent of patients satisfied with their long-term outcome and 94.1 percent willing to have the surgery again. Although nearly 10 percent of patients resumed taking antisecretory medication, in most no evidence of reflux recurrence could be found."
"In conclusion, the results of this study do not differ significantly from the data reported in the literature, suggesting that laparoscopic antireflux surgery is an effective long-term procedure, is well tolerated, and can be properly used in the treatment of GERD," the authors write.
JAMA and Archives Journals
"In this study, the intraoperative and postoperative complication rates were 2.1 percent and 2.6 percent, respectively, with a subsequent operation rate of 4.4 percent at five years," the researchers report. "Of interest, overall patient satisfaction following surgery was high, with 93.1 percent of patients satisfied with their long-term outcome and 94.1 percent willing to have the surgery again. Although nearly 10 percent of patients resumed taking antisecretory medication, in most no evidence of reflux recurrence could be found."
"In conclusion, the results of this study do not differ significantly from the data reported in the literature, suggesting that laparoscopic antireflux surgery is an effective long-term procedure, is well tolerated, and can be properly used in the treatment of GERD," the authors write.
JAMA and Archives Journals
Reflux Disease Current Events and Reflux Disease News RSSReflux esophagitis due to immune reaction, not acute acid burn, UT Southwestern researchers report
Contrary to current thinking, a condition called gastroesophageal reflux disease (GERD) might not develop as a direct result of acidic digestive juices burning the esophagus, UT Southwestern Medical Center researchers have found in an animal study.
Commentary warns of unexpected consequences of proton pump inhibitor use in reflux disease
Despite being highly effective and beneficial for many patients, unexpected consequences are emerging in patients who are prescribed proton pump inhibitors (PPIs) for reflux diseases.
Barrett's esophagus patients have same survival rates as general population
New Mayo Clinic research has found that survival rates of patients with Barrett's esophagus, which can be a precursor for esophageal cancer, are no different than the survival rates for the general population.
GERD negatively impacts sleep quality, results in considerable economic burden
There has been much debate about the relationship between gastroesophageal reflux disease (GERD) and sleep.
GERD patient satisfaction hinges on medication type and physician bedside manner
Patient satisfaction with their medications and the quality of interactions with their doctor reflect the success of gastroesophageal reflux disease (GERD) therapy, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute.
University of Saskatchewan and Canadian Synchrotron researchers shed light on esophageal disease
Canadian Light Source (CLS) staff scientist Luca Quaroni and Dr. Alan Casson, Head of the Department of Surgery at the University of Saskatchewan (U of S) used the synchrotron's infrared microscope to identify tissue afflicted with a condition known as Barrett's Esophagus from chemical fingerprints associated with the disease, which can lead to esophageal cancer.
NEJM study finds radiofrequency ablation can reverse Barrett's esophagus, reduce cancer risk
Patients who have gastroesophageal reflux disease (GERD) for a prolonged period have an increased risk of developing Barrett's esophagus, a pre-cancerous condition where the tissue lining the esophagus becomes damaged by stomach acid and transformed into something like the inside of the stomach.
Obesity predicts inadequate bowel prep at colonoscopy
Obesity is an independent predictor of inadequate bowel preparation at colonoscopy, and the presence of additional risk factors further increases the likelihood of a poorly cleansed colon.
Technique eradicates problems in most patients with Barrett's esophagus
A procedure that uses heat generated by radio waves to treat Barrett's esophagus, a condition caused by acid reflux (severe heartburn), can eliminate signs of the potentially cancer-causing disorder and reduce the risk that the disease will progress.
Use of acid-suppressive medications associated with increased risk of hospital-acquired pneumonia
Hospitalized patients who receive acid-suppressive medications such as a proton-pump inhibitor have a 30 percent increased odds of developing pneumonia while in the hospital.
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