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New imaging technique reveals how likely you are to break a bone
October 26, 2005Scientists have developed a technique which can be used to reveal the strength of bones, allowing doctors to more accurately estimate the risk of bone fracture.
According to research published online in the Journal of Bone Mineral Research, scientists have developed a laser imaging technique which can more fully assess the strength of bones, a technique the scientists hope can be used to predict the likelihood of young women developing osteoporosis in later life.
Dr Edward Draper of Imperial College London and the Royal Veterinary College, and lead researcher, said: "Traditionally, the only way to predict bone strength has been through X-rays, but these can only measure part of the strength of the bone. Using this new technique we can get a more complete measurement, allowing us to predict better the risk of fractures as a result of osteoporosis."
Although X-rays can be used to measure bone strength, they can only be used to measure bone mineral density, which only accounts for part of the strength. The new Raman spectroscopic technique allows scientists to measure the collagen, which also affects bone strength by eliminating the spectral components of overlying tissues.
The scientists plan to develop this work into a test for women during adolescence to predict the likelihood of osteoporosis developing in later life. By taking steps earlier on, such as increasing exercise to build up bone mass, this could prevent the need for more interventions such as Risedronate (Actonel) later.
Dr Draper adds: "We hope we can further develop this technique, and use it as part of a national screening programme which hopefully could be done in any GP's surgery. By identifying the risk of any problems developing early enough, this could not only make an enormous difference to the health of individuals, but could help the NHS by negating the need for more extreme and costly interventions later."
The research team are from Imperial College London, the Royal Veterinary College, University College London, University of Michigan, Hospital for Special Surgery, New York, and the Rutherford Appleton Laboratory, UK, spectral components of overlying tissues.
Imperial College London
Although X-rays can be used to measure bone strength, they can only be used to measure bone mineral density, which only accounts for part of the strength. The new Raman spectroscopic technique allows scientists to measure the collagen, which also affects bone strength by eliminating the spectral components of overlying tissues.
The scientists plan to develop this work into a test for women during adolescence to predict the likelihood of osteoporosis developing in later life. By taking steps earlier on, such as increasing exercise to build up bone mass, this could prevent the need for more interventions such as Risedronate (Actonel) later.
Dr Draper adds: "We hope we can further develop this technique, and use it as part of a national screening programme which hopefully could be done in any GP's surgery. By identifying the risk of any problems developing early enough, this could not only make an enormous difference to the health of individuals, but could help the NHS by negating the need for more extreme and costly interventions later."
The research team are from Imperial College London, the Royal Veterinary College, University College London, University of Michigan, Hospital for Special Surgery, New York, and the Rutherford Appleton Laboratory, UK, spectral components of overlying tissues.
Imperial College London
Bone Current Events and Bone News RSSFlaxseed oil and osteoporosis
Animal studies suggest that adding flaxseed oil to the diet could reduce the risk of osteoporosis in post-menopausal women and women with diabetes, according to a report to be published in the International Journal of Food Safety, Nutrition and Public Health.
Multiple health concerns surface as winter, vitamin D deficiences arrive
A string of recent discoveries about the multiple health benefits of vitamin D has renewed interest in this multi-purpose nutrient, increased awareness of the huge numbers of people who are deficient in it, spurred research and even led to an appreciation of it as "nature's antibiotic."
Scientists watch as peptides control crystal growth with 'switches, throttles and brakes'
By producing some of the highest resolution images of peptides attaching to mineral surfaces, scientists have a deeper understanding how biomolecules manipulate the growth crystals. This research may lead to a new treatment for kidney stones using biomolecules.
Gene mismatch influences success of bone marrow transplants
A commonly inherited gene deletion can increase the likelihood of immune complications following bone marrow transplantation, an international team of researchers reports in the November 22 advance online issue of Nature Genetics.
New cancer target for non-Hodgkin's lymphoma
Physician-scientists from Weill Cornell Medical College have discovered a molecular mechanism that may prove to be a powerful target for the treatment of non-Hodgkin's lymphoma, a type of cancer that affects lymphocytes, or white blood cells.
Bone Implant Offers Hope for Skull Deformities
A synthetic bone matrix offers hope for babies born with craniosynostosis, a condition that causes the plates in the skull to fuse too soon.
'Hobbits' are a new human species -- according to the statistical analysis of fossils
Researchers from Stony Brook University Medical Center in New York have confirmed that Homo floresiensis is a genuine ancient human species and not a descendant of healthy humans dwarfed by disease.
U of M researchers find 2 units of umbilical cord blood reduce risk of leukemia recurrence
A new study from the Masonic Cancer Center, University of Minnesota shows that patients who have acute leukemia and are transplanted with two units of umbilical cord blood (UCB) have significantly reduced risk of the disease returning.
Heart and bone damage from low vitamin D tied to declines in sex hormones
Researchers at Johns Hopkins are reporting what is believed to be the first conclusive evidence in men that the long-term ill effects of vitamin D deficiency are amplified by lower levels of the key sex hormone estrogen, but not testosterone.
Surgeon 'gluing' the breastbone together after open-heart surgery
An innovative method is being used to repair the breastbone after it is intentionally broken to provide access to the heart during open-heart surgery. The technique uses a state-of-the-art adhesive that rapidly bonds to bone and accelerates the recovery process.
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