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New small RNAs found
December 16, 2005Dr. Kathleen Collins and a graduate researcher in her lab at UC Berkeley have identified a second RNAi pathway in Tetrahymena thermophilia - introducing a heretofore unprecedented layer of complexity to small RNA biology in unicellular organisms.
The researchers describe a distinct class of 23-24-nt small RNAs that accumulate ubiquitously throughout the Tetrahymena life cycle. This novel class of small RNAs has unique features compared with the previously identified class of 27-30-nt RNAs in Tetrahymena, suggesting that they participate in a second, distinct RNAi pathway.
Suzanne Lee, first author on the study, explains that "further study of this new class of small RNAs will allow us to elucidate the diversity of sRNA functions in Tetrahymena and discover mechanisms for biogenesis and regulation with potential implications for sRNAs in other systems."
Cold Spring Harbor Laboratory
Cold Spring Harbor Laboratory
RNAs Current Events and RNAs News RSSTrembling hands and molecular handshakes
Fragile X tremor/ataxia syndrome (FXTAS) is a recently recognized condition, which is actually one of the most prevalent heritable neurodegenerative diseases.
Researchers discover RNA repair system in bacteria
In new papers appearing this month in Science and the Proceedings of the National Academy of Sciences, University of Illinois biochemistry professor Raven H. Huang and his colleagues describe the first RNA repair system to be discovered in bacteria.
How RNA polymerase II gets the go-ahead for gene transcription
All cells perform certain basic functions. Each must selectively transcribe parts of the DNA that makes up its genome into RNAs that specify the structure of proteins.
UCSF scientists illuminate how microRNAs drive tumor progression
UCSF researchers have identified collections of tiny molecules known as microRNAs that affect distinct processes critical for the progression of cancer.
Small molecule inhibits pathology associated with myotonic dystrophy type 1
Researchers at the University of Illinois have designed a small molecule that blocks an aberrant pathway associated with myotonic dystrophy type 1, the most common form of muscular dystrophy.
Predicting cancer prognosis
Researchers led by Dr. Soheil Dadras at the Stanford University Medical Center have developed a novel methodology to extract microRNAs from cancer tissues.
Scripps Research scientists find early evolution maximized the 'spellchecking' of protein sequences
As letters of the alphabet spell out words, when amino acids are linked to one another in a particular order they "spell out" proteins.
Link uncovered between viral RNA and human immune response
In its fight against an intruding virus, an enzyme in our immune system may sense certain types of viral RNA pairs, according to scientists.
Parasites ready to jump
Transposons are mobile genetic elements found in the hereditary material of humans and other organisms. They can replicate and the new copies can insert at novel sites in the genome.
International research team seeks to unravel flatworm regeneration
Planarian flatworms are only a few millimeters up to a few centimeters in length, live in freshwater and are the object of intense research, because they possess the extraordinary ability to regenerate lost tissue with the help of their stem cells (neoblasts) and even grow an entirely new worm out of minute amputated body parts.
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HP C8257A 12V Auto Power Adapter by Hewlett Packard Information technology professionals rely on HP quality to ensure maximum productivity. As the power of applications, processors, memory adapters and storage devices increases, high-end computer users are seeking ways to optimize their system performance. HP provides leading solutions, adding new levels of performance, availability, flexibility, and management. |
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