 |
|
New method for examining cost-effectiveness of new drugs for chronic illnesses
December 30, 2005In a comprehensive analysis and mathematical model of the available scientific data, researchers at the University of York on behalf of the National Institute of Health and Clinical Excellence (NICE) in the United Kingdom found that newer drugs used to treat the most common forms of epilepsy are more expensive than older drugs, but produce similar health benefits.
The analysis, published in the September 2005 issue of Medical Decision Making (MDM), a publication of the Society for Medical Decision Making, focuses on the cost-effectiveness of epileptic drugs licensed for adults in three specific situations. The objective of the study was to consolidate available evidence, to bring it together within a decision model, and to quantify the uncertainty associated with cost effectiveness.
Comparing different drugs for epilepsy has been difficult because there are few head-to-head trials of different agents, and because the observed rates of patient withdrawal from the drugs change over time. The investigators applied new methods of analyzing drug effectiveness data to overcome these problems. These methods, they argue, will be of value for evaluating the effectiveness and cost of drug therapies for other chronic conditions.
Epilepsy affects almost 3,000,000 people in the US and UK alone. The study by Hawkins et al compared three situations: monotherapy for newly diagnosed patients, monotherapy for refractory patients, and combination therapy for refractory patients. The analysis separately considers partial and generalized seizures. Drug therapy is the main treatment for epilepsy, but there is not a uniform approach to the selection or sequencing of anti-epileptic drug (AED) therapies.
The analysis showed that, based on existing studies, two older drugs, valproate and carbamazepine, are likely to be more cost-effective than newer agents for newly diagnosed patients with partial seizures. Valproate was shown to be most cost-effective for newly diagnosed patients with generalized seizures. For some other groups of patients, such as those who did not respond well to a single agent, newer drugs such as topiramate, Oxcarbazepine, or Lamotrigine, were cost-effective. For example, oxcarbazepine is probably the most cost-effective adjunctive therapy for refractory patients with partial seizures, and adjunctive topiramate was more cost-effective than monotherapy for refractory patients with generalized seizures.
SAGE Publications
Epilepsy affects almost 3,000,000 people in the US and UK alone. The study by Hawkins et al compared three situations: monotherapy for newly diagnosed patients, monotherapy for refractory patients, and combination therapy for refractory patients. The analysis separately considers partial and generalized seizures. Drug therapy is the main treatment for epilepsy, but there is not a uniform approach to the selection or sequencing of anti-epileptic drug (AED) therapies.
The analysis showed that, based on existing studies, two older drugs, valproate and carbamazepine, are likely to be more cost-effective than newer agents for newly diagnosed patients with partial seizures. Valproate was shown to be most cost-effective for newly diagnosed patients with generalized seizures. For some other groups of patients, such as those who did not respond well to a single agent, newer drugs such as topiramate, Oxcarbazepine, or Lamotrigine, were cost-effective. For example, oxcarbazepine is probably the most cost-effective adjunctive therapy for refractory patients with partial seizures, and adjunctive topiramate was more cost-effective than monotherapy for refractory patients with generalized seizures.
SAGE Publications
Chronic Illnesses Current Events and Chronic Illnesses News RSSCigarettes Harbor Many Bacteria Harmful to Human Health
Cigarettes are "widely contaminated" with bacteria, including some known to cause disease in people, concludes a new international study conducted by a University of Maryland environmental health researcher and microbial ecologists at the Ecole Centrale de Lyon in France.
American Dietetic Association Releases Updated Position Paper Promoting and Supporting Breastfeeding
The American Dietetic Association has released an updated position paper on breastfeeding that details health benefits for both infants and mothers and encourages promotion of breastfeeding whenever possible.
Progress made on group B streptococcus vaccine
Scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have completed a Phase II clinical study that indicates a vaccine to prevent Group B Streptococcus (GBS) infection is possible.
Study: depression can lead to inflated reports of physical symptoms
New research shows people who feel depressed tend to recall having more physical symptoms than they actually experienced. The study indicates that depression -- not neuroticism -- is the cause of such over-reporting.
Patients with chronic rhinosinusitis have increased incidence of other chronic illnesses
Patients who suffer from chronic rhinosinusitis (CRS) also tend to suffer from other chronic illnesses, like asthma, hypertension, and arthritis.
Nanoparticle-based battlefield pain treatment moves step closer
University of Michigan scientists have developed a combination drug that promises a safer, more precise way for medics and fellow soldiers in battle situations to give a fallen soldier both morphine and a drug that limits morphine's dangerous side effects.
Survival rates for elderly receiving hospital CPR did not improve from 1992 to 2005
A study of elderly patients receiving CPR in the hospital shows that rates of survival did not improve from 1992 to 2005.
Asthma rates and where you live
Neighborhoods with restaurants, entertainment, cultural facilities and ethnic diversity have lower asthma rates in the city of Chicago than neighborhoods where residents are less likely to move, and where there are more churches and not-for-profit facilities.
Peer-to-peer heart monitoring
The possibility of remote monitoring for chronically ill patients will soon become a reality. Now, researchers in South Africa and Australia have devised a decentralized system to avoid medical data overload. They describe the peer-to-peer system in a forthcoming issue of the International Journal of Computer Applications in Technology.
Penn study: Breast cancer survivors call for more 'survivorship care' from primary care physicians
As the nation's growing population of breast cancer survivors ages, many patients will likely develop common chronic illnesses like diabetes and heart disease, and they'll need specialized care to balance those problems with the late effects of cancer therapies they received.
More Chronic Illnesses Current Events and Chronic Illnesses News Articles
 |
Chronic Illness: Impact and Intervention by Pamala D. Larsen (Author), Ilene Morof Lubkin (Author) The new edition of best-selling Chronic Illness: Impact and Intervention continues to focus on the various aspects of chronic illness that influence both patients and their families. Topics include the sociological, psychological, ethical, organizational, and financial factors, as well as individual and system outcomes. The Seventh Edition has been completely revised and updated and includes new chapters on Models of Care, Culture, Psychosocial Adjustment, Self-Care, Health Promotion, and Symptom Management. |
 |
Medical and Psychosocial Aspects of Chronic Illness and Disability by Donna R. Falvo (Author) Medical and Psychosocial Aspects of Chronic Illness and Disability, Fourth Edition covers the medical aspects of the conditions most commonly encountered by rehabilitation and other health professionals and discusses symptoms, diagnoses, treatments, and prognoses. The Fourth Edition has been completely revised and updated and includes new chapters on Conceptualizing Chronic Illness and Disability; Intellectual Disability; and Financing Rehabilitation. In addition, chapters on Psychiatric Disability, Substance Use, and Conditions of the Blood and Immune System have been expanded. |
 |
The Lebed Method, Focus on Healing Through Therapeutic Exercise and Movement Starring: Participants in DVD havingBreast CancerColon CancerLymphedema upper and lowerArthritisHip replacementBack SurgeryHepititis CFibromyalsiaOther Chronic Illness Directed By: Sherry Lebed Davis/Michelle Mansfield The Lebed Method, Focus on Healing through Therapeutic Exercise and movement is for everyone who has or who has had Breast Cancer all Cancers, Lymphedema, M.S. Parkinson's, Fibromyalgia and all Chronic Illnesses. We welcome you to our medically based program that is in more than 14 countries and has served thousands of people in those countries and is in more than 500 hospitals and centers world wide. The benefits of this program: Can be done sitting or standing Designed for all fitness levels Helps increase energy & Combat Fatigue May Help reduce swelling from Lymphedema Helps decrease frozen shoulder Helps increase Range of Motion Improves Quality of Life Helps decrease depression strengthens muscles increases flexibility improves balance fun and easy too! |
 |
FULL TILT: How to Reclaim your Life In Spite of Living with a Chronic Illness. Sheila Shaw (Performer) Finally, Sheila Shaw, CEO of Patient s Pride, has made her story available on an audio CD and reveals her secrets that helped her make it through some of the darkest times in her life! This CD was also inspired by the thousands of patients, caregivers, and nurses who have shared their stories, grievances, and concerns with her. It is Sheila s hope that you too will be inspired to reach forward and live the life that you deserve. It doesn t matter what kind of chronic illness you may have! All patients, nurses, doctors, and caregivers will benefit from the information on this CD! Listen to this CD and you will: Awaken each day feeling inspired and motivated Learn to take back control of your life Learn to bring out the best in your medical team Develop a new... |
|
Candidiasis, Hidden Cause of Chronic Illness Also With: Ralph Luciani (Primary Contributor) | |
 |
Chronic Illness Awareness Ribbon Mouse Pad by MyHeritageWear.com The Chronic Illness Ribbon proudly displayed on a mouse pad. There is no better way to achieve awareness for the meaning of the Chronic Illness Ribbon than to display it on your mouse pad for everyone to see. The mouse pad measures at 9.25 x 7.75, it is machine washable, and the colors will not fade or run. Start gaining awareness today by presenting your Chronic Illness Ribbon mouse pad at work or at home. It is certain to keep your mouse rolling in style all while gaining support and awareness! |
 |
Chronic Fatigue, Fibromyalgia & Enviromental Illness by Life Extension Chronic fatigue, fibromyalgia and environmental illness can be permanently reversed using non-toxic alternative medicine treatments. In this book, 26 leading physicians explain the techniques and natural substances that brought complete recovery to their |
 |
Just Fine: Unmasking Concealed Chronic Illness And Pain by Carol Sveilich (Author) Nearly everyone knows someone who is living with a health challenge that is difficult, if not impossible, to detect in their appearance and demeanor. "Just Fine" discusses this dichotomy of looking one way while feeling quite another. This topic is explored not only with words, but with original portraits, because the true story of looking one way while feeling quite differently requires both. No other book has approached hidden health disorders in this manner. It is a powerful and telling tale that must be told as well as shown. Sveilich interviewed and photographed over 50 people of all ages and from all walks of life who live with a wide variety of concealed disorders. She also consulted with numerous medical and mental health professionals to explore the juxtaposition of looking... |
 |
Healing Prayer for Chronic Illness Pastor Gwendolyn Henderson (Primary Contributor) |
 |
I Don't Have Tourettes, Youre just An Asshole Men's Hoodie Sweat Shirt XXXXL, Black by 99 Volts |
| © 2009 BrightSurf.com |