 |
|
Statins have neutral effect on risk of cancer
January 04, 2006The cholesterol-lowering medications called statins do not appear to reduce the incidence of cancer or cancer deaths, according to a meta-analysis of previous studies in the January 4 issue of JAMA.
Other studies have suggested that statins reduce the risk of developing cancer, the authors provide as background information in the review article. "Statins have been studied in numerous large-scale, randomized, active- or placebo-controlled trials for primary and secondary prevention of coronary artery disease. In these trials, statins reduced the risk of a first myocardial infarction (heart attack) and overall mortality. With long-term follow-up and collection of cancer data in a majority of studies, insight into the risk of cancer among statin-naĆ-ve persons and statin users can be derived," the authors write.
C. Michael White, Pharm.D., from the University of Connecticut and Hartford Hospital, Hartford, Conn., and colleagues, conducted a search of the medical literature from 1966 through July 2005 to identify randomized controlled trials of statins. They found 27 articles (n = 86,936 participants) that met their criteria for inclusion, reporting 26 randomized controlled trials of statins with data on either cancer incidence (n = 20 studies) or cancer death (n = 22 studies).
"In our current meta-analysis, statins did not reduce the incidence of cancer or cancer death," the authors report. "No reductions were noted for cancers of the breast, colon, gastrointestinal tract, prostate, respiratory tract, or skin (melanoma) when statins were used." The authors continue, " the patients in our meta-analysis were primarily treated with simvastatin and pravastatin. As such, we evaluated pravastatin alone and simvastatin alone on cancer incidence and death and found no impact."
"Statins have a neutral effect on cancer and cancer death risks in randomized controlled trials," the authors write in conclusion. \\\
JAMA and Archives Journals
"In our current meta-analysis, statins did not reduce the incidence of cancer or cancer death," the authors report. "No reductions were noted for cancers of the breast, colon, gastrointestinal tract, prostate, respiratory tract, or skin (melanoma) when statins were used." The authors continue, " the patients in our meta-analysis were primarily treated with simvastatin and pravastatin. As such, we evaluated pravastatin alone and simvastatin alone on cancer incidence and death and found no impact."
"Statins have a neutral effect on cancer and cancer death risks in randomized controlled trials," the authors write in conclusion. \\\
JAMA and Archives Journals
Statin Current Events and Statin News RSSVitamin B niacin offers no extra benefit to statin therapy in seniors already diagnosed with CAD
The routine prescription of extended-release niacin, a B vitamin (1,500 milligrams daily), in combination with traditional cholesterol-lowering therapy offers no extra benefit in correcting arterial narrowing and diminishing plaque buildup in seniors who already have coronary artery disease, a new vascular imaging study from Johns Hopkins experts shows.
Early end to key study on benefits of niacin, a B vitamin, in keeping arteries open was premature
Heart experts at Johns Hopkins are calling premature the early halt of a study by researchers at Walter Reed Army Medical Center and Washington Hospital Center on the benefits of combining extended-release niacin, a B vitamin, with cholesterol-lowering statin medications to prevent blood vessel narrowing.
Statins show dramatic drug and cell dependent effects in the brain
Besides their tremendous value in treating high cholesterol and lowering the risk of heart disease, statins have also been reported to potentially lower the risks of other diseases, such as dementia.
Adding ezetimibe to atorvastatin improves lipid control
Adding ezetimibe to atorvastatin significantly boosted the attainment of lipid targets as specified by both Canadian and European guidelines in elderly patients aged 65 and older and the combination produced superior results than simply increasing the dose of atorvastatin alone.
Elevated arginase levels contribute to vascular eye disease such as diabetic retinopathy
Elevated levels of the enzyme arginase contribute to vascular eye damage and Medical College of Georgia researchers say therapies to normalize its levels could halt progression of potentially blinding diseases such as diabetic retinopathy.
New heart disease risk score outperforms existing test
An independent external validation of QRISK - a new score for predicting a person's risk of heart disease - has shown that it performs better than the existing test and should be recommended for use in the United Kingdom by the National Institute for Health and Clinical Excellence (NICE).
New heart disease risk score should be recommended in the UK, say experts
A new score for predicting a person's risk of heart disease performs better than the existing test and should be recommended for use in the United Kingdom by the National Institute for Health and Clinical Excellence (NICE).
New tool finds best heart disease and stroke treatments for patients with diabetes
Researchers from North Carolina State University and Mayo Clinic have developed a computer model that medical doctors can use to determine the best time to begin using statin therapy in diabetes patients to help prevent heart disease and stroke.
More patients across the world lowering 'bad' cholesterol
The percentage of patients lowering their elevated "bad" cholesterol to within target levels nearly doubled in the last decade, according to a multi-national survey reported in Circulation: Journal of the American Heart Association.
Statins can protect against Alzheimer's disease, according to new study
High cholesterol levels are considered to be a risk factor not only for cardiovascular disease including stroke, but also for the development of Alzheimer's disease.
More Statin Current Events and Statin News Articles
 |
Statin Drugs Side Effects and the Misguided War on Cholesterol by Duane Graveline (Author) If you are on a statin drug or are thinking of going on a statin, this fully referenced book, Statin Drug Side Effects, is a "must read" for you. The unacceptable legacy of statin drug use at today's high doses is a trail of chronic aches and pains, numbness, weakness, confusion, fatigue, shortness of breath and even heart failure in hordes of unsuspecting victims. Only by knowing this information, and in consultation with your healthcare professional, can you make an informed decision about your health care. If you are a user of Vytorin, Lipitor, Zocor, Crestor, Mevacor, Pravachol or Lescol you must read this book. Most of the statin side effects I discuss are unknown to your busy doctor. Although knowledgeable about muscle and liver problems, few have heard of statin amnesia and... |
 |
The Statin Damage Crisis by Duane Graveline (Author), Malcolm Kendrick (Introduction) The purpose in the choice of the title The Statin Damage Crisis is to draw attention to the thousands of statin damaged people who have written to Dr Graveline about their disabling neuropathies, myopathies and a variety of neurodegenerative conditions such as ALS and Parkinsonism associated with statin use. Although much of the book's content will be familiar to readers of Statin Drugs Side Effects, ( this was originally planned as a new edition ) the Statin Damage Crisis adds much new material that Dr Graveline has learned of in the past two years. Dr Graveline states: "Early on my NASA doctors told me my amnesia response to statins was nothing but a coincidence but I persevered to write my first book, Lipitor, Thief of Memory." "Then I learned of statin damage to nerves and... |
 |
What You Must Know About Statin Drugs & Their Natural Alternatives by Jay S. Cohen (Author) |
 |
Triumph of the Heart: The Story of Statins by Jie Jack Li (Author) Over 25 million people in the U.S. alone have benefited from statins--such drugs as Lipitor, Zocor, Crestor, Pravachol, and other cholesterol-lowering medicines--in preventing stroke, heart attack, and other forms of coronary heart disease. But how did these remarkable, life-saving drugs come into being? In Triumph of the Heart, Dr. Jie Jack Li, a medicinal chemist and expert on drug discovery, tells for the first time the fascinating story of statins. Drawn from discussions with many scientists involved in the discovery and development of these drugs, the book illuminates the human side of science by revealing the role played by persistence, luck, and sudden insight that characterize major discoveries. For scientists in the drug industry, health care professionals, students of medicine,... |
 |
Aidan C-Statin - 120 Capsules by Aidan C-Statin, a naturally occurring plant extract, contains a patented proteoglycan molecule (PGM) from field bindweed that is a potent angiogenesis inhibitor. Studies have demonstrated PGM to be 100 times stronger than shark cartilage. Used and recommended by healthcare professionals around the world. C-STATIN is a proprietary extract of Convolvulus arvensis hat contains high concentrations of active PGMs. |
|
Statin the Facts by P. | |
 |
Statin Boy & Cholesterol Kid by Today's Icons Wall sculpture depicting modern day icons, cholsterol and its antidote Statin pill, ready for hanging! |
 |
Blackhawk 6" Statin Chrome Blackhawk Adjustable Wr by Blackhawk Adjustable - Wrenches Tool Type: Adjustable Wrench Overall Length: 6 Opening Size: 15/16 Finish/Coating: Matt Chrome |
|
FLUSH MOUNT CEILING SUB STATIN by Aiphone | |
 |
NIKE FLEXON NIKE 6004 421 STATIN BROWN 50MM FULL-FRAME. by Nike * NIKE FLEXON NIKE 6004 421 STATIN BROWN 51MM FULL-FRAME * NIKE CASE + CLEANING CLOTH. |
| © 2009 BrightSurf.com |