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Whooping cough-making a comeback?
February 14, 2006Whooping cough (pertussis) is most easily diagnosed in young children because they develop a characteristic cough-paroxysms of coughing followed by a long inspiration that makes a whooping sound. However, infants, immunized children, adolescents and adults do not usually exhibit whooping cough. Indeed, adolescents and adults may experience only a persistent cough. As a result, the disease is underdiagnosed, undertreated and can be spread to others.
The introduction of a whole-cell vaccine in the 1940s resulted in a dramatic decrease in the incidence of pertussis. The disease, however, made a comeback in the 1990s, probably because of waning immunity, which occurs 6-12 years after the last episode of illness or booster dose. A new (less toxic) acellular vaccine introduced in the 1990s has had some effect, but again, recently, the incidence of pertussis has increased. The highest increase in rates of the disease in the 1990s was among adolescents and adults. Since 2004, authorities have recommended that adolescents receive a booster dose of pertussis vaccine.
Eleni Galanis and colleagues discuss these trends and their implications for both patients and physicians. The changing epidemiology of pertussis in Canada in the 1990s has led to the emergence of new groups at higher risk of the disease: young infants, adolescents and adults.
Canadian Medical Association Journal
Canadian Medical Association Journal
Whooping Cough News and Current Whooping Cough Events RSSMost vaccine-allergic children can still be safely vaccinated, Hopkins experts say
With close monitoring and a few standard precautions, nearly all children with known or suspected vaccine allergies can be safely immunized, according to a team of vaccine safety experts led by the Johns Hopkins Children's Center.
Combination vaccines okay for infants, study shows
A University of Rochester study brings relief to new parents who, while navigating a jam-packed childhood vaccine schedule, can expect to soothe their newborn through as many as 15 "pokes" by his or her six-month checkup.
Infectious diseases experts issue blueprint to avert
New vaccines are available to make significant gains against cervical cancer deaths and debilitating pain from shingles, but infectious diseases experts warn that their full potential will not be realized without changes in the way vaccines for adults and adolescents are promoted, financed, and delivered in the United States.
Family members most often source of whooping cough in young infants
Infants with whooping cough were most likely infected by the people they live with, according to a multi-country study led by researchers from the University of North Carolina at Chapel Hill School of Public Health.
Biodegradable microspheres deliver time release vaccines, stimulate different immune response
A new vaccine delivery system using microspheres of a biodegradable polymer may not only reduce the need for booster shots in some cases, but also appears to stimulate an immune response that traditional vaccines do not.
Antibiotics unnecessarily prescribed for acute bronchitis
Antibiotics are routinely prescribed unnecessarily for acute bronchitis, according to Virginia Commonwealth University findings published in today's issue of the New England Journal of Medicine.
Scientists discover toxin that causes gastro disease
Australian scientists have identified a highly potent toxin that causes severe gastrointestinal illnesses, including food poisoning.
States that easily grant immunization exemptions have higher incidence of whooping cough
States that have personal belief exemptions for school immunization requirements, and exemptions that are easily obtained, have higher rates of new cases of pertussis (whooping cough) than states in which obtaining immunization exemptions is more difficult.
Researcher hits bulls-eye for antibiotic target
A Purdue University researcher has opened the door for possible antibiotic treatments for a variety of diseases by determining the structure of a protein that controls the starvation response of E. coli.
Structure of key enzyme in plague bacterium found
Researchers at the National Institute of Standards and Technology (NIST) have solved the structure of a key enzyme from the bacterium responsible for plague, finding that it has a highly unusual configuration. The results may shed light both on how the bacterium kills and on fundamental cell signaling processes.
More Whooping Cough News Articles
| Dpt: A Shot in the Dark by Harris L. Coulter, Barbara Fisher | |
| Growing Interest in Selective Pertussis Reimmunization.: An article from: Family Practice News by Bruce Jancin This digital document is an article from Family Practice News, published by International Medical News Group on November 15, 1999. The length of the article is 751 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web... | |
| Experts debate responses to pertussis rise.(Infectious Diseases): An article from: Pediatric News by Alicia Ault This digital document is an article from Pediatric News, published by International Medical News Group on December 1, 2004. The length of the article is 921 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.Citation... | |
| A serious address on the dangerous consequences of neglecting common coughs and colds, with methods of cure: And successful directions for the prevention ... observations on the hooping cough and asthma by Thomas Hayes | |
| Gale Encyclopedia of Medicine: Whooping cough by Rosalyn Carson-DeWitt MD The article is excerpted from Gale Encyclopedia of Medicine. Consult the second edition of this authoritative, comprehensive, in-depth medical guide for information on more than 1,700 medical topics in language accessible to adult laypersons. Presented in a single alphabetical sequence, articles range in length from one or two paragraphs for minor topics, to several pages or more for major... | |
| What's behind the resurgence in pertussis cases? Most U.S. outbreaks, defined as more than five cases, were in schools over the 1999-2003 period.(News): An article from: Family Practice News by Alicia Ault This digital document is an article from Family Practice News, published by International Medical News Group on December 15, 2004. The length of the article is 923 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web... | |
| Outbreaks of pertussis associated with hospitals--Kentucky, Pennsylvania, and Oregon, 2003.: An article from: Morbidity and Mortality Weekly Report by K. Bryant, K. Brothers, K. Humbaugh, V. Kistler, S. Stites, S. Madeja, J.A. Jahre, S.J. Schweon, B. Coyle, C. Kalman, T.L. Burger, P. Lurie, H. Stafford, P. Tran, T. Metcalf This digital document is an article from Morbidity and Mortality Weekly Report, published by U.S. Government Printing Office on January 28, 2005. The length of the article is 2846 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web... | |
| On the pathology of hooping-cough by Graily Hewitt | |
| The history of diphtheria, scarlet fever, measles and whooping cough in Australia, 1788-1925 (Australia. Department of Health. Service publication) by J. H. L Cumpston | |
| Proceedings of the Sixth International Symposium on Pertussis, Jack Masur Auditorium, Warren Grant Magnuson Clinical Center, National Institutes of Health, ... 26-28, 1990 (SuDoc HE 20.4002:P 43/2) by U.S. Dept of Health and Human Services |
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