 |
|
U of MN researchers identify new cord blood stem cell
February 14, 2006Discovery suggests potential treatment for regenerating nerve tissue after stroke
Researchers at the University of Minnesota Medical School have discovered a new population of cells in human umbilical cord blood that have properties of primitive stem cells.
Umbilical cord blood is generally known to contain hematopoietic stem cells that can only produce cells found in blood. The new findings, however, identify a small population of cord blood cells with the characteristics of more primitive stem cells that have the potential to produce a greater variety of cell types.
"We are excited by this discovery because it provides additional insight into how stem cells can restore function in the brain after injury," said Walter Low, Ph.D., senior investigator of the study, and professor of Neurosurgery and the Stem Cell Institute at the University of Minnesota.
This research was published in the latest issue of the journal Stem Cells and Development.
Transplantation of these human cord blood stem cells into laboratory rodents with experimental strokes resulted in significant reductions in the size of brain lesion, and improved these animals' use of their limbs.
Some of the transplanted stem cells developed into "neuron-like" cells that are typically found in the brain. In addition, the transplanted cells also induced an unanticipated reorganization of host nerve fibers within the brain, which may explain why the rats regained function, Low said.
University of Minnesota
"We are excited by this discovery because it provides additional insight into how stem cells can restore function in the brain after injury," said Walter Low, Ph.D., senior investigator of the study, and professor of Neurosurgery and the Stem Cell Institute at the University of Minnesota.
This research was published in the latest issue of the journal Stem Cells and Development.
Transplantation of these human cord blood stem cells into laboratory rodents with experimental strokes resulted in significant reductions in the size of brain lesion, and improved these animals' use of their limbs.
Some of the transplanted stem cells developed into "neuron-like" cells that are typically found in the brain. In addition, the transplanted cells also induced an unanticipated reorganization of host nerve fibers within the brain, which may explain why the rats regained function, Low said.
University of Minnesota
Research on the effects of stem cell source and patient age on transplantation outcomes
Blood cancers - leukemia, lymphoma, and myeloma - are typically treated with a combination of treatments including chemotherapy, biological therapy, radiation therapy, and stem cell transplantation. Stem cell transplantation is the process by which blood stem cells are collected from a donor, or from the patient prior to chemotherapy, and then infused into the patient after treatment.
More Cord Blood Stem Cell Current Events and Cord Blood Stem Cell News Articles
 |
Cord Blood: Establishing a National Hematopoietic Stem Cell Bank Program by Committee on Establishing a National Cord Blood Stem Cell Bank Program (Author), Emily Ann Meyer (Editor), Kathi Hanna (Editor), Kristine Gebbie (Editor) With the potential for self-renewal and differentiation, the possibilities for stem cells are enormous. One specific type of stem cell, the hematopoietic progenitor cell (HPC), which is derived from umbilical cord blood (as well as adult bone marrow and mobilized peripheral blood), holds particular promise. To make the most of these HPCs, the Institute of Medicine was asked to consider the optimal structure for a national cord blood program and to address pertinent issues related to maximizing the potential of stem cell technology. "Cord Blood: Establishing a National Hematopoietic Stem Cell Bank Program" examines: the role of cord blood in stem cell transplantation; the current status of blood banks already in existence; the optimal structure for the cord blood program; the current use... |
 |
ABC News Nightline Banking on your Future Storing umbilical cord blood is a growing phenomenon. Private cord blood banks across the country are providing storage for thousands of parents and there are a lot of parents out there who think they will be letting their children down if they don't participate. The question is, how useful are they? And if storing cord blood is a useful thing to do, should there be more public cord blood banks accessible to everyone, including those who might not be able to afford private banks? ABC News will examine the science and the social implications of this new trend in medicine. Is it an example of a scientific breakthrough vital to all, or an example of 'boutique medicine' dividing those with means from those without? Anchor: Ted Koppel Airdate: 10/4/2005 This product is manufactured on... |
|
Discover the Power of Stem Cells Also With: various (Primary Contributor) | |
|
Bill promotes use of cord blood stem cells in treating disease.(From the Hill): An article from: Issues in Science and Technology by Thomson Gale (Publisher) This digital document is an article from Issues in Science and Technology, published by Thomson Gale on January 1, 2004. The length of the article is 553 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Bill promotes use of cord blood stem cells in treating disease.(From the Hill) Publication: Issues in Science and Technology (Magazine/Journal) Date: January 1, 2004 Publisher: Thomson Gale Volume: 20 Issue: 2 Page: 21(2) Distributed by Thomson... | |
|
Cord Blood Stem Cells Yielding Clinical Benefits.: An article from: Family Practice News by Timothy F. Kirn (Author) This digital document is an article from Family Practice News, published by International Medical News Group on September 15, 2001. The length of the article is 1431 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Cord Blood Stem Cells Yielding Clinical Benefits. Author: Timothy F. Kirn Publication: Family Practice News (Magazine/Journal) Date: September 15, 2001 Publisher: International Medical News Group Volume: 31 Issue: 18 Page: 12 Distributed by Thomson... | |
|
Umbilical Cord Blood Stem Cell Use Increases.(Brief Article): An article from: Pediatric News by Timothy F. Kirn (Author) This digital document is an article from Pediatric News, published by International Medical News Group on September 1, 2001. The length of the article is 922 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Umbilical Cord Blood Stem Cell Use Increases.(Brief Article) Author: Timothy F. Kirn Publication: Pediatric News (Magazine/Journal) Date: September 1, 2001 Publisher: International Medical News Group Volume: 35 Issue: 9 Page: 4 Article Type: Brief Article Distributed by Thomson... | |
|
Bill establishing a national cord blood stem cell bank introduced in House.(Cord Blood Stem Cell Act of 2005): An article from: Transplant News by Transplant Communications, Inc. (Publisher) This digital document is an article from Transplant News, published by Transplant Communications, Inc. on March 31, 2005. The length of the article is 519 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Bill establishing a national cord blood stem cell bank introduced in House.(Cord Blood Stem Cell Act of 2005) Publication: Transplant News (Newsletter) Date: March 31, 2005 Publisher: Transplant Communications, Inc. Volume: 15 Issue: 6 Distributed by Thomson... | |
|
Thermogenesis requests reexamination of PharmaStem cord blood stem cell patent.(ThermoGenesis Corp.): An article from: BIOTECH Patent News by Biotech Patent News (Publisher) This digital document is an article from BIOTECH Patent News, published by Biotech Patent News on May 1, 2004. The length of the article is 483 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Thermogenesis requests reexamination of PharmaStem cord blood stem cell patent.(ThermoGenesis Corp.) Publication: BIOTECH Patent News (Newsletter) Date: May 1, 2004 Publisher: Biotech Patent News Volume: 18 Issue: 5 Distributed by Thomson Gale | |
|
Advances in cord blood stem cell transplants prompts bi-partisan effort to establish national network.: An article from: Transplant News by Jim Warren (Author) This digital document is an article from Transplant News, published by Transplant Communications, Inc. on October 31, 2003. The length of the article is 824 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Advances in cord blood stem cell transplants prompts bi-partisan effort to establish national network. Author: Jim Warren Publication: Transplant News (Newsletter) Date: October 31, 2003 Publisher: Transplant Communications, Inc. Volume: 13 Issue: 20 Distributed by Thomson... | |
|
Establishment of National Cord Blood Stem Cell Bank Program inching its way through Congress.: An article from: Transplant News by Transplant Communications, Inc. (Publisher) This digital document is an article from Transplant News, published by Transplant Communications, Inc. on March 9, 2004. The length of the article is 749 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Establishment of National Cord Blood Stem Cell Bank Program inching its way through Congress. Publication: Transplant News (Newsletter) Date: March 9, 2004 Publisher: Transplant Communications, Inc. Volume: 14 Issue: 5 Distributed by Thomson... |
| © 2009 BrightSurf.com |