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Study of early estrogen's effect on heart disease similar to WHI findings
March 01, 2006Researchers in The Department of Obstetrics, Gynecology & Reproductive Sciences at Yale have launched the Kronos Early Estrogen Prevention Study (KEEPS), which will further understanding of the possible beneficial effects on the heart and arteries and/or quality of life in recently menopausal women.
The study will explore whether beginning hormone therapy in women during the menopausal transition (ages 42 to 58) protects against atherosclerosis, the major cause of heart attacks.
This study is supported by the recent release of results from the Women's Health Initiative (WHI). That study initially suggested that there were few benefits of estrogen on atherosclerosis. The National Institutes of Health halted the study in 2002. Women in WHI were postmenopausal, with a mean age of 63, yet most women begin hormone treatment much younger, at the onset of menopausal symptoms. Today's study reports the results by age. The younger women, those 50 to 59-years-old, who used estrogen showed a beneficial effect on the heart.
"These findings are consistent with estrogen having a beneficial effect if used early, but a negative effect if used late," said Principal Investigator of the KEEPS trial at Yale, Hugh S. Taylor, M.D. "Estrogen seems to work by limiting the progression of atherosclerotic changes rather than treating established disease. You can't turn back the clock. Estrogen works by preventing disease, but it doesn't work if one goes for years without it. Newly menopausal women can use estrogen for relief of hot flushes and other menopausal symptoms without worrying about their heart. Women close to menopause might even see benefits for their heart."
The Yale team is seeking 90 healthy, recently menopausal women ages 42 to 58 for the trial that will study the effects of using pill and skin patch hormone therapy.
Compensation will be provided for participants accepted into the study.
Yale University
"These findings are consistent with estrogen having a beneficial effect if used early, but a negative effect if used late," said Principal Investigator of the KEEPS trial at Yale, Hugh S. Taylor, M.D. "Estrogen seems to work by limiting the progression of atherosclerotic changes rather than treating established disease. You can't turn back the clock. Estrogen works by preventing disease, but it doesn't work if one goes for years without it. Newly menopausal women can use estrogen for relief of hot flushes and other menopausal symptoms without worrying about their heart. Women close to menopause might even see benefits for their heart."
The Yale team is seeking 90 healthy, recently menopausal women ages 42 to 58 for the trial that will study the effects of using pill and skin patch hormone therapy.
Compensation will be provided for participants accepted into the study.
Yale University
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Study shows hormone replacement therapy decreases mortality in younger postmenopausal woman
Hormone replacement therapy (HRT) to treat menopausal estrogen deficiency has been in widespread use for over 60 years. Several observational studies over the years showed that HRT use by younger postmenopausal women was associated with a significant reduction in total mortality; available evidence supported the routine use of HRT to increase longevity in postmenopausal women.
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Source Naturals Phyto-Estrogen Cream, 4 oz (113.4 g) by Source Naturals Advanced liposomal delivery. Non-GMO soy. Phyto-Estrogen Cream offers some of the finest phytoestregens, renowned for use during menopause. Each ounce contains 60 mg of isoflavone phytoestrogens, along with 150 mg of pomegranate juice extract, and 100 mg of red clover extract. Micro-penetrating liposomes pass through skin layers more easily than non-liposomal creams. |
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Natural Estrogen with Pomegranate Extract, 60 caplets by Life Extension Natural Estrogen with Pomegranate Extract60 caplets Item Catalog Number: 712 In an attempt to provide aging women with the multiple health effects of the bodies’ estrogen without side effects, scientists have discovered plant extracts with estrogenic activity (phytoestrogens). Natural Estrogen with Pomegranate Extract is one answer to the concerns of maintaining healthy hormone function. A review of the published literature reveals some interesting findings about how plant-derived estrogens can provide safe and effective support for such menopausal symptoms as hot flashes. Derived from organically-grown fruit, the pomegranate extract in this formula has the same ratio of polyphenols found in the whole fruit and all the benefits one would get from the juice without the sugar, calories,... |
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Estrogen/Estriol (Bio-Identical) Fragrance Free Cream 2 oz. Pump Bottle by Radiant Laboratories - Made In USA Paraben-Free and Unscented. Menopausal Hot Flashes? Night Sweats? Trouble Sleeping? Replenish Your Estrogen Naturally and Safely. Get your life back! Estriol Has Been Used in Europe for Years. Bio-identical Hormones Are Safe and Effective. Non Prescription Bio-identical Natural Estrogen (Estriol Usp) Not to Be Confused with Phyto-estrogens. Bio-identical Hormones Are Safe for Women Help Relieve Menopause Symptoms. Estriol is not a phyto estrogen. Don't confuse phyto estrogens with pure natural estriol USP. The natural estrogen, estriol USP, is made the same way natural progesterone USP is made. Sterol analogues found in many varieties of plants are combined with specific bacteria and the resulting hormone is bio identical in chemical structure to the hormone produced by the human body.... |
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Emerita Phytoestrogen Body Cream with Black Cohosh, 2-Ounce Tube by Emerita Peri/Menopause support. Paraben-free. Who knew a little tube of cream could change the world? In 1978 we had a revolutionary idea: that there was not enough real choice when it came to peri / menopause. So we created Pro-Gest, Phytoestrogen Cream and Pers |
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