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Fat cells around coronary arteries may play a role in heart disease
April 05, 2006The fat cells that surround coronary arteries may play a central and previously unrecognized role in development of cardiovascular disease, according to a study by University of Iowa researchers.
Dr. Lynn Stoll presented the research team's findings on April 4 at Experimental Biology 2006 in San Francisco. Her presentation was part of the scientific program of the American Society of Investigative Pathology.
Once thought of as mere storage depots for excess energy, fat cells ("adipocytes") are now known to be highly active metabolically, releasing potent pro-inflammatory proteins and hormones that regulate inflammation, blood pressure, insulin activity, and other biological processes. Where fat cells are located has a major influence on their impact, as seen in the fact that visceral fat surrounding the internal organs ("apple" body shape) is far more highly correlated with development of diabetes and cardiovascular disease than subcutaneous fat in the thighs and buttocks (pear\\\
Federation of American Societies for Experimental Biology
Federation of American Societies for Experimental Biology
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Fat Cells Current Events and Fat Cells News RSSTrimming the fat boosts blood recovery after marrow transplant
Seeking ways to improve blood recovery after chemotherapy or bone marrow transplant, researchers at Children's Hospital Boston have discovered that fat cells, which accumulate in bone marrow as people age, inhibit the marrow's ability to produce new blood cells.
Overweight male teens with normal blood pressures showing signs of heart damage
AUGUSTA, Ga. - Even while their blood pressures are still normal, overweight male teens may have elevated levels of a hormone known to increase pressures as well as early signs of heart damage, researchers say.
UCSF discovers new glucose-regulating protein linked with diabetes
Researchers at the University of California, San Francisco, and collaborators at Harvard Medical School have linked a specialized protein in human muscles to the process that clears glucose out of the bloodstream, shedding light on what goes wrong in type 2 diabetes on a cellular level.
Researchers identify biological markers that may indicate poor breast cancer prognosis
A team of researchers has found an association between breast cancer survival and two proteins that, when present in the blood in high levels, are indicators of inflammation.
Turmeric extract suppresses fat tissue growth in rodent models
Curcumin, the major polyphenol found in turmeric, appears to reduce weight gain in mice and suppress the growth of fat tissue in mice and cell models.
Heart disease patients carrying extra pounds do better, live longer
Being overweight or obese is a leading contributor to cardiovascular disease (CVD) and associated risk factors; however, in patients with established CVD, obesity appears to play a protective role.
Triglycerides implicated in diabetes nerve loss
A common blood test for triglycerides - a well-known cardiovascular disease risk factor - may also for the first time allow doctors to predict which patients with diabetes are more likely to develop the serious, common complication of neuropathy.
Cold and brown fat raise the prospect of a new method of treating obesity
It has previously been believed that the brown fat found in infants disappears as we grow up, but the new study shows that this is not the case.
Findings show insulin - not genes - linked to obesity
Researchers have uncovered new evidence suggesting factors other than genes could cause obesity, finding that genetically identical cells store widely differing amounts of fat depending on subtle variations in how cells process insulin.
Bad news for insomniacs: 'hunger hormones' affected by poor sleep
Insomnia has long been associated with poor health, including weight gain and even obesity. Now researchers at UCLA have found out why.
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ABC News Nightline Stem Cell Breakthrough for Suffering Pets" Stem Cell Breakthrough for Suffering Pets: Stem cell therapy for humans has long been mired in ethical debates. But for animals, the therapy is already here. By injecting animals with their own adult stem cells, common pet maladies, like hip dysplasia and arthritis, can be improved 70 percent of the time. California's Vet-Stem laboratories has developed the groundbreaking procedure, harvesting the regenerative cells from the animals' fat deposits. Can the procedure one day be adapted for humans? Hillary Clinton: Sen. Hillary Clinton's surprise victory in New Hampshire last night was especially welcome at her campaign headquarters, a much-needed rebound after a third-place finish in last week's Iowa caucuses. Was her emotional moment before the primary the difference? Driving Smart: We... |
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