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Tiny particles may pose threat to liver cells, say scientists
April 05, 2006Researchers at the University of Edinburgh are to study the effects of nanoparticles on the liver. In a UK first, the scientists will assess whether nanoparticles -already found in pollution from traffic exhaust, but also used in making household goods such as paint, sunblock, food, cosmetics and clothes- can cause damage to the cells of the liver.
Nanoparticles are atoms and molecules 80,000 times smaller than the width of a human hair, with various properties according to their composition, which explains their widespread usage. Airborne nanoparticles present in traffic exhaust are already known to enter the lungs and affect human health.
Scientist Dr Celine Filippi explains: "In experiments carried out elsewhere to mimic environmental exposure, nanoparticles delivered into the lungs crossed the lung barrier and entered the blood. Particles in the blood can reach the liver, amongst other organs. We also know that nanoparticles directly injected into the blood for medical purposes are also likely to end up in the liver.
"We don't yet know if the nanoparticles are safely eliminated from the liver by specialised cells or whether these extremely small particles can enter the liver cells and disrupt their normal functioning. Our research will try to establish whether nanoparticles, which are set to be used increasingly in industry and the manufacture of household goods, can damage the cells of the liver."
Professor Ken Donaldson, Professor of Respiratory Toxicology at the University of Edinburgh said: "We are looking at the new idea that the liver is a target for nanoparticles, and a lot more work needs to be done to assess the levels and impact of nanoparticles reaching the liver.\\\
University of Edinburgh
"We don't yet know if the nanoparticles are safely eliminated from the liver by specialised cells or whether these extremely small particles can enter the liver cells and disrupt their normal functioning. Our research will try to establish whether nanoparticles, which are set to be used increasingly in industry and the manufacture of household goods, can damage the cells of the liver."
Professor Ken Donaldson, Professor of Respiratory Toxicology at the University of Edinburgh said: "We are looking at the new idea that the liver is a target for nanoparticles, and a lot more work needs to be done to assess the levels and impact of nanoparticles reaching the liver.\\\
University of Edinburgh
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PATH Malaria Vaccine Initiative shares strategy for developing 'next-generation' malaria vaccines
Marking its tenth anniversary year, the PATH Malaria Vaccine Initiative (MVI) today unveiled a new strategy that sets the stage for an aggressive push targeting the long-term goal of eliminating and eradicating malaria. Malaria is one of the world's deadliest infectious diseases, killing nearly 900,000 people a year, most of them children in sub-Saharan Africa.
Scientists develop novel method to generate functional hepatocytes for drug testing
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How RNA polymerase II gets the go-ahead for gene transcription
All cells perform certain basic functions. Each must selectively transcribe parts of the DNA that makes up its genome into RNAs that specify the structure of proteins.
UCSD researchers pave the way for effective liver treatments
A combination of bioengineering and medical research at the University of California, San Diego has led to a new discovery that could pave the way for more effective treatments for liver disease.
Governor recognizes stem cell research at Einstein
Albert Einstein College of Medicine of Yeshiva University hosted a roundtable discussion on stem cell research with New York Governor David A. Paterson today.
Liver cells grown from patients' skin cells
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Pitt researchers net $5 million from NIH to explore better ways to grow cells for regenerative medicine
Regenerative medicine researchers at the University of Pittsburgh received two grants totaling more than $5 million from the National Institutes of Health (NIH) to explore new methods for cultivating replacement cells from existing tissues and organs.
Second-hand smoking results in liver disease, study finds
A team of scientists at the University of California, Riverside has found that even second-hand tobacco smoke exposure can result in nonalcoholic fatty liver disease (NAFLD), a common disease and rising cause of chronic liver injury in which fat accumulates in the liver of people who drink little or no alcohol.
Novel bacterial strains clear algal toxins from drinking water
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Cooperation of Liver Cells in Health and Disease by Z. Kmiec (Author) Medical Univ. of Gdansk, Poland. Summarizes multiple data suggesting the role of cellular cross-talk for the functions of normal and diseased liver. Includes a concise presentation of the majority of detailed data in 18 tables. Expanded-outline format. Softcover. DNLM: Hepatocytes--physiology. |
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Historic Print (XL): [Normal liver cells, abnormal liver cells that have increased in size, and abnormal live by Library Images This is a museum quality, reproduction print on premium paper with archival/UV resistant inks. Date: [published 1858] Subject: Notes: Illus. and text in: Die Cellularpathologie / Rudolf Ludwig Karl Virchow. Berlin : A. Hirschwald, 1858, p. 58. Published in: The tradition of science / Leonard C. Bruno. Washington, D.C. : Library of Congress, 1987, p. 166. Format: Scientific illustrations 1850-1860.Engravings 1850-1860. SOURCE: Library of Congress |
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Pure Encapsulations - Liver-G.I. Detox 120c by Pure Encapsulations Pure Encapsulations - Liver-G.I. Detox 120c |
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Source Naturals Skin Eternal Plus, with C Ester, DMAE, and Lipoic Acid, Tablets, 120 tablets by Source Naturals Dietary supplement. Bio-align. Skin Eternal Plus is a Bio-Aligned formula that supports healthy, supple skin. Its ingredients including ascorbyl palmitate, alpha-lipoic acid, DMAE, Vitamin E, and grape seed extract, address the primary body systems involved in skin health. These include cell membrane integrity, connective tissue support cell renewal, blood and liver cleansing, muscle and nerve function, stress response, and antioxidant defense. (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.) |
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Cell Guard COQ-10/ N-A-C - 60 - Tablet by Source Naturals, Inc. "Cell Guard is a combination of potent antioxidants and other vital nutrients, to enrich and protect the micronutritional environment of your cells. Cell Guard includes the antioxidants beta carotene, vitamin E, selenium and N-acetyl cysteine (NAC). NAC is itself an antioxidant and a precursor to glutathione, another antioxidant that assists in the liver's detoxification pathways. Cell Guard also furnishes coenzyme Q10. This antioxidant plays an important role in the Krebs cycle, which converts food into energy by producing the high-energy molecule ATP. Cell Guard also supplies a unique herbal blend, including astragalus and the adaptogen ginseng, to support your well-being." |
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Liver Cells and Drugs b | |
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Liver Stem Cells (Medical Intelligence Unit) by Stewart Sell (Author), Zoran Ilic (Author) G. Landes). Albany Medical College, New York. Research on the nature and role of the tissue-determined liver stem cell in normal development, in response to injury and in hepatocarcinogenesis, and its potential use in transplantation and gene therapy. DNLM: Liver--cytology. | |
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Historic Print (S): [Normal liver cells, abnormal liver cells that have increased in size, and abnormal live by Olde Yankee Map and Photo Shoppe This is a museum quality, reproduction print on premium paper with archival/UV resistant inks. The framed work is single matted (ivory), under acrylic glass, with a hanging wire. Date: [published 1858] Subject: Notes: Illus. and text in: Die Cellularpathologie / Rudolf Ludwig Karl Virchow. Berlin : A. Hirschwald, 1858, p. 58. Published in: The tradition of science / Leonard C. Bruno. Washington, D.C. : Library of Congress, 1987, p. 166. Format: Scientific illustrations 1850-1860.Engravings 1850-1860. SOURCE: Library of Congress |
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New Body 7 Day Cleanse Kit (Deluxe) by New Body Products -"ARE YOU READY FOR A NEW BODY?"- It's said that all sickness begins in the colon and then spreads to other parts of the body. The purpose of the colon is to expel the toxins and wastes that it collects from other organs in the body. When waste matter sits in our colon, it allows protiens to putrefy, fats become rancid, and carbohydrates ferment. Even with one bowel movement per day, you will still have at least two meals worth of waste matter puterfying in your colon at all times. If the colon is not operating efficiently and not kept cleansed of encrusted toxins and waste, then it will begin recycling waste back into the bloodstream and accumulate in our organs. The longer your body is exposed to these conditions, the more risk of absorbing these dangerous intestinal toxins, causing... |
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Milk Thistle 175mg - 60 - Capsule by Bluebonnet MILK THISTLE EXTRACT 175 mg. Vcaps Pure Indena® milk thistle seed extract imported from Europe. Including e - d - s, an enzyme delivery system from 100% plant sources. Available in easy-to-swallow vegetable capsules for maximum assimilation and absorption. |
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