Science Current Events | Science News | Brightsurf.com
 

NYU, Austrian researchers create non-invasive imaging method with advantages over conventional MRI

April 25, 2006
New York University's Alexej Jerschow, an assistant professor of chemistry, and Norbert Müller, a professor of chemistry at the University of Linz in Austria, have developed a completely non-invasive imaging method. Their work offers the benefits of magnetic resonance imaging (MRI) while eliminating patients' exposure to irradiation and setting the stage for the creation of light, mobile MRI technology. The research, which appears in the latest issue of the Proceedings of the National Academy of Sciences (PNAS), was supported by the National Science Foundation.

MRI allows clinicians to non-invasively visualize soft tissue in the interior of the human body through the application of radiofrequency (rf) irradiation. However, the rf pulses of MRI machines deposit heat in patients and medical staff, though safety regulations that limit energy deposition have long been established. Jerschow and Müller have devised a low-energy, nuclear magnetic resonance (NMR) technique that does not require external rf-irradiation. Their technique, instead, relies on the detection of spontaneous, proton spin-noise in a tightly coupled rf-cavity.

In order to reconstruct spin-noise images that characterize MRI, the researchers used a commercial, liquid-state NMR spectrometer equipped with a cryogenically cooled probe. The sample, a phantom of four glass capillaries filled with mixtures of water and heavy water, remained at room temperature. The authors inserted the sample into a standard NMR tube and applied a magnetic field gradient to acquire spatial encoding information. They collected 30, one-dimensional images, and after applying a projection reconstruction algorithm, obtained the phantom's two-dimensional image. Because of its low-energy deposition, Müller and Jerschow's imaging technique may enable new application areas for magnetic resonance microscopy. Using already-developed methods, the researchers expect expansion to three-dimensional imaging to be straightforward.

The same detection scheme is applicable to NMR spectroscopy. Very delicate samples, such as explosives could be investigated with this method. Preliminary investigations also predict a sensitivity advantage over conventional experiments at length scales of millimeters to micrometers, which may be important in the measurement of NMR spectra within microfluidic devices.

Very strong magnetic fields, as generally required for MRI and NMR, can be avoided with the spin-noise detection scheme, making possible the development of extremely portable and minimally invasive MRI and NMR instruments.

New York University


Related Non-invasive Imaging Current Events and Non-invasive Imaging News Articles


New light for old master paintings
A painting hanging on the wall in an art gallery tells one story. What lies beneath its surface may tell quite another.

Novel imaging technique improves prostate cancer detection
In 2014, prostate cancer was the leading cause of newly diagnosed cancers in men and the second leading cause of cancer death in men.

Customising chemotherapy in Lu Ca: New Ph II data reported in 2 LB studies
Measuring the expression levels of an enzyme involved in DNA synthesis can help predict the response of lung cancers to certain treatments, a Korean study has shown at the ESMO 2014 Congress in Madrid.

Imaging autoimmune diabetes
Researchers at Lund University have managed to develop a technique whereby they can study the inflammatory process that takes place in the pancreas during the natural development of type 1 diabetes, allowing for real time and repeated non-invasive imaging of individual islets of Langerhans.

Your first hug: how the early embryo changes shape
In research published today in Nature Cell Biology, scientists from the EMBL Australia research team based at Monash University's Australian Regenerative Medicine Institute (ARMI) have revealed new insights into how cells organise and form an early mammalian embryo.

Imaging technique detects pediatric liver disease without need for needle biopsy
A new, non-invasive imaging technique, magnetic resonance elastography (MRE), can now help physicians accurately detect fibrosis (scarring) in children with chronic liver disease - a growing problem due in part to increasing obesity rates.

Quitting smoking drops heart attack risk to levels of never smokers
Dr Min said: "Smoking is an established risk factor for cardiovascular disease. Studies have identified that quitting smoking can reduce heart attacks and death but have not examined the relationship of this salutary effect on the presence and severity of coronary artery disease (CAD). Our study aimed to find out what impact stopping smoking had on the risk of cardiovascular events, death and the severity of CAD."

NYU and NYU Langone researchers devise method for enhancing CEST MRI
Researchers at New York University and NYU Langone Medical Center have created a novel way to enhance MRI by reducing interference from large macromolecules that can often obscure images generated by current chemical exchange saturation transfer (CEST) methods.

Secrets of human speech uncovered
A team of researchers at UC San Francisco has uncovered the neurological basis of speech motor control, the complex coordinated activity of tiny brain regions that controls our lips, jaw, tongue and larynx as we speak.

Team creates new view of body's infection response
A new 3-D view of the body's response to infection - and the ability to identify proteins involved in the response - could point to novel biomarkers and therapeutic agents for infectious diseases.
More Non-invasive Imaging Current Events and Non-invasive Imaging News Articles

Non Invasive Diagnostic Techniques in Clinical Dermatology

Non Invasive Diagnostic Techniques in Clinical Dermatology
by Enzo Berardesca (Editor), Howard Maibach (Editor), Klaus Wilhelm (Editor)


This book is a comprehensive but compact guide to the latest technical and technological developments in the growing field of non invasive diagnosis in clinical dermatology. Information is provided on the practical and technical characteristics of a wide range of equipment and methods for in vivo measurements that aid in the investigation of skin function, the evaluation of topically applied products and the monitoring of skin disease. Individual sections are devoted to imaging techniques, skin analysis, superficial skin analysis, skin mechanics, water and stratum corneum hydration and erythema and blood flow. All of the authors are experts in the field, with detailed knowledge of the techniques they describe. Non Invasive Diagnostic Techniques in Clinical Dermatology will be of value for...

Practical Phlebology: Venous Ultrasound

Practical Phlebology: Venous Ultrasound
by Joseph Zygmunt (Author), Olivier Pichot (Author), Tracie Dauplaise (Author)


Authored by three of the leading world experts in phlebology, Venous Ultrasound is an essential text for anyone involved in the treatment of chronic venous disease. It provides specific information on ultrasound as it is applied to chronic insufficiency, including history, general techniques, examples of anatomy, and protocols for performing ultrasound on patients. Focusing on the fundamentals that every phlebologist needs to know, the book includes color illustrations and numerous line drawings for a complete learning experience. Key features: • Covers anatomy related to venous insufficiency • Includes useful diagrams and images to aid understanding • Thoroughly up to date, with all the latest information for those practicing venous therapies Venous Ultrasound will be invaluable...

Handbook of Non-Invasive Methods and the Skin, Second Edition

Handbook of Non-Invasive Methods and the Skin, Second Edition
by Jorgen Serup (Editor), Gregor B. E. Jemec (Editor), Gary L. Grove (Editor)


Firmly established as the leading international reference in this field, Non-Invasive Methods and the Skin broke new ground with its comprehensive coverage of methods used in both clinical and experimental dermatology. Completely revised and updated, containing more than twice as much information, the Second Edition continues the tradition. The authors' thorough research and clear organization make this book a baseline reference for those using noninvasive biophysical methods to study the skin.

Arranged by physical modality and structured to provide educational and practical information, the second edition, like its predecessor, will prove to be of value to young researchers and senior scientists alike. The coverage of major evaluation and measurement methods share a consistent...

Non-Invasive Thermometry of the Human Body

Non-Invasive Thermometry of the Human Body
by Michio Miyakawa (Author), J. Ch. Bolomey (Author)


This exciting book describes the latest technology in non-invasive thermometry that measures temperature distribution, with discussions focusing on image-based techniques. This is the first book devoted entirely to this topic. An international team of experts detail all important techniques for possible non-invasive thermometry. Descriptions of each technique explain in depth the principles of measurement, the measurement system, obtained temperature image, and the future prospects for the method.

Electromyography: Physiology, Engineering, and Non-Invasive Applications

Electromyography: Physiology, Engineering, and Non-Invasive Applications
by Roberto Merletti (Editor), Philip J. Parker (Editor)


A complete overview of electromyography with contributions from pacesetters in the field In recent years, insights from the field of engineering have illuminated the vast potential of electromyography (EMG) in biomedical technology. Featuring contributions from key innovators working in the field today, Electromyography reveals the broad applications of EMG data in areas as diverse as neurology, ergonomics, exercise physiology, rehabilitation, movement analysis, biofeedback, and myoelectric control of prosthesis. Bridging the gap between engineering and physiology, this pioneering volume explains the essential concepts needed to detect, understand, process, and interpret EMG signals using non-invasive electrodes. Electromyography shows how engineering tools such as models and signal...

Non-Invasive Surrogate Markers of Atherosclerosis

Non-Invasive Surrogate Markers of Atherosclerosis
by Steven B. Feinstein (Editor)


Non-Invasive Surrogate Markers of Atherosclerosis details the scientific and clinical support for using non-invasive imaging modalities to evaluate the presence of surrogate markers of atherosclerosis, in conjunction with traditional methods of diagnosing cardiovascular disease. This new book covers the topic completely and explores some of the following:

Atlas of Non-Invasive Coronary Angiography by Multidetector Computed Tomography (Developments in Cardiovascular Medicine)

Atlas of Non-Invasive Coronary Angiography by Multidetector Computed Tomography (Developments in Cardiovascular Medicine)
by Guillem Pons-Llado (Editor), Ruben Leta-Petracca (Editor)


This atlas presents over 160 illustrations, with 116 in color, and illustrates the capacity of multidetector CT for the analysis of the anatomy of the coronary arteries. The multidetector CT scanner speeds diagnosis and treatment of patients. One of its many uses is to perform CT coronary angiography. Multidetector CT provides clear pictures and takes less time than other non-invasive techniques. The book is written by cardiologists and radiologists.

Case Files Critical Care (LANGE Case Files)

Case Files Critical Care (LANGE Case Files)
by Eugene Toy (Author), Terrence Liu (Author), Manuel Suarez (Author)


SHARPEN YOUR CRITICAL THINKING SKILLS AND IMPROVE PATIENT CARE Experience with clinical cases is key to mastering the art and science of medicine and ultimately to providing patients with competent clinical care. Case Files: Critical Care provides 42 true-to-life cases that illustrate essential concepts in critical care. Each case includes an easy-to-understand discussion correlated to key concepts, definitions of key terms, clinical pearls, and board-style review questions to reinforce your learning. With Case Files, you'll learn instead of memorize. Learn from 42 high-yield cases, each with board-style questions Master key concepts with clinical pearls Practice with review review questions to reinforce learning Polish your approach to clinical problem-solving and to patient care...

Imaging of Carotid Artery Stenosis

Imaging of Carotid Artery Stenosis
by Bernhard Schaller (Editor)


This atlas is an up-to-date reference work on imaging in carotid artery stenosis written by internationally renowned experts. The authors take the reader step-by-step through illustrated descriptions of state-of-the-art imaging techniques that they have helped to develop and demonstrate that these techniques are crucial in the management of patients. This book covers all facets of imaging in carotid artery stenosis and gives an outlook to future aspects. At the end of each chapter, special "take-home-messages" offer quick help in daily practice.

Non-Invasive Imaging of Atherosclerosis (Developments in Cardiovascular Medicine) 1st edition by Mercuri, Michele published by Springer Hardcover

Non-Invasive Imaging of Atherosclerosis (Developments in Cardiovascular Medicine) 1st edition by Mercuri, Michele published by Springer Hardcover
by Springer (Publisher)




© 2015 BrightSurf.com