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Secret herb in tests to stop breast cancer patients' hot flushes and night sweats
April 28, 2006Researchers at the University of Manchester are testing a secret herb in a bid to stop the severe hot flushes that besiege breast cancer patients on hormone treatment.
Professor Alex Molassiotis, of the School of Nursing, Midwifery and Social Work, says the herb-one of the mint family, found in any kitchen-is thought to stop the hot flushes and night sweats which can be so bad that some women have to change their clothes three or four times a night.
It is traditionally used by Mediterranean women undergoing the menopause, but Professor Molassiotis cannot name it as he and his team are carrying out a double blind trial (neither the patient nor the doctor is allowed to know whether they are in the group taking the herb or a placebo).
The women are taking hormone treatment to lower oestrogen and progesterone levels as these affect the growth of some breast cancer cells. This can lead to early or revisiting menopause with symptoms such as anxiety, dry skin, bone thinning and hot flushes, with some women having up to 30 flushes a day. It is too risky for them to take Hormone Replacement Therapy (HRT) as this will increase the hormone levels again. Instead they are advised to cut out tea, coffee and nicotine, try alternative remedies or a certain type of anti-depressant.
Professor Molassiotis said: "It is hoped that the herbal remedy will be simpler and cheaper to take, as well as more effective, thus improving the lives of women who need all their energy to fight the disease."
He and his team are now recruiting 170 volunteers for the randomized trial, half of whom will take the phytooestrogen herb in the form of a pill and half of whom will take a placebo, from Greater Manchester and Cheshire. Only breast cancer patients who have or are receiving hormone treatments for their cancer are allowed to take part, and only if they experience at least one hot flush a day of moderate and above severity for at least a month. The treatment will be for a total of three months, taking one pill a day. The team will assess the volunteers' hot flushes four times over six months from starting the trial with questionnaires and a blood sample.
University of Manchester
The women are taking hormone treatment to lower oestrogen and progesterone levels as these affect the growth of some breast cancer cells. This can lead to early or revisiting menopause with symptoms such as anxiety, dry skin, bone thinning and hot flushes, with some women having up to 30 flushes a day. It is too risky for them to take Hormone Replacement Therapy (HRT) as this will increase the hormone levels again. Instead they are advised to cut out tea, coffee and nicotine, try alternative remedies or a certain type of anti-depressant.
Professor Molassiotis said: "It is hoped that the herbal remedy will be simpler and cheaper to take, as well as more effective, thus improving the lives of women who need all their energy to fight the disease."
He and his team are now recruiting 170 volunteers for the randomized trial, half of whom will take the phytooestrogen herb in the form of a pill and half of whom will take a placebo, from Greater Manchester and Cheshire. Only breast cancer patients who have or are receiving hormone treatments for their cancer are allowed to take part, and only if they experience at least one hot flush a day of moderate and above severity for at least a month. The treatment will be for a total of three months, taking one pill a day. The team will assess the volunteers' hot flushes four times over six months from starting the trial with questionnaires and a blood sample.
University of Manchester
Hot Flushes Current Events and Hot Flushes News RSSIntermittent androgen deprivation at least as effective as continuous androgen deprivation
Potential Benefits of Intermittent Androgen Suppression Therapy in the Treatment of Prostate Cancer: A Systematic Review of the Literature' is the title of an article by P-A. Abrahamsson in the January issue of European Urology, the official journal of the European Association of Urology.
Study of adjuvant endocrine treatment for breast cancer reveals cost of noncompliance
The largest study in the world of treatments for post menopausal, hormone positive breast cancer has shown that patients who continue to take exemestane or tamoxifen do significantly better than patients who start to take one or other drug (or tamoxifen followed exemestane) but then stop.
Acupuncture 'probably ineffective' in treatment of hot flushes
Acupuncture cannot be shown to have any positive effect on hot flushes during the menopause.
Hormone replacement therapy improves sleep, sexuality and joint pain in older women
One of the world's longest and largest trials of hormone replacement therapy (HRT) has found that post-menopausal women on HRT gain significant improvements in quality of life.
Major study shows significant quality-of-life benefits from HRT
A major international study of the effects of HRT use on quality of life has shown that HRT use can significantly improve well-being in women with menopausal symptoms such as hot flushes and night sweats.
Acupuncture relieves hot flushes in breast cancer patients taking tamoxifen
Acupuncture provides effective relief from hot flushes in women who are being treated with the anti-oestrogen tamoxifen following surgery for breast cancer, according to new research presented today (Friday) at the 6th European Breast Cancer Conference (EBCC-6) in Berlin.
Study of early estrogen's effect on heart disease similar to WHI findings
Researchers in The Department of Obstetrics, Gynecology & Reproductive Sciences at Yale have launched the Kronos Early Estrogen Prevention Study (KEEPS), which will further understanding of the possible beneficial effects on the heart and arteries and/or quality of life in recently menopausal women.
Side-effects cause some breast cancer patients to skip hormone treatment
A study by UK researchers of over 200 breast cancer patients receiving hormone treatments such as tamoxifen has found that nearly two-thirds would prefer to take a tablet daily and around a quarter would prefer a monthly injection, given that both treatments would be equally effective and have similar side-effects.
Studies on HRT for breast cancer patients can give false hopes
Women treated for breast cancer who are considering taking Hormone Replacement Therapy (HRT) should be cautious when using published research to inform their decision. An article published today in the journal Breast Cancer Research reveals that qualitative studies on the recurrence of breast cancer in breast cancer survivors undergoing HRT are unreliable.
New research shows that the seasons may be involved in onset of menopause
Research by Hungarian fertility experts published today (Thursday 10 June) in Europe's leading reproductive medicine journal Human Reproduction[1], has revealed that the onset of the menopause[2] may not be dictated only by the fact that a woman's lifetime supply of eggs are running low, but also by changes in the seasons. Analysis of reliable questionnaires from over 100 patients at the menopause clinic at Baranya County Teaching Hospital in Pécs, revealed that the spring and autumn equinoxes played a conspicuous role in the timing of the menopause. "We found that there was a high peak after the spring equinox and another, lower one, after the autumn equinox," said research leader D
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