Periodontitis may increase C-reactive protein levels in pregnancyMay 03, 2006C-reactive protein might be a plausible mediator of the association CHICAGO - Researchers found that pregnant women with periodontitis had 65 percent higher C-reactive protein (CRP) levels compared to periodontally healthy women. This study appears in the May issue of the Journal of Periodontology (JOP). CRP levels are a marker of systemic inflammation and are associated with periodontal disease, a chronic bacterial infection found in the gums of the mouth. CRP has also been associated with adverse pregnancy outcomes, including preeclampsia and preterm delivery. "Elevated CRP may indeed be caused by periodontal infection and inflammation." said Dr. Waranuch Pitiphat, Department of Community Dentistry, Faculty of Dentistry, Khon Kaen University, Thailand. "If this is the case, CRP could amplify the inflammatory response and ultimately cause adverse pregnancy outcomes. Alternatively, periodontal disease and CRP may share a common risk factor for predisposing individuals to a hyperinflammatory response. More research is clearly needed to further our understanding about the association between periodontal disease and adverse pregnancy outcomes." Past studies examining the relationship between periodontal disease and CRP found that often after standard non-surgical periodontal therapy, CRP levels decrease. "This is one more study that really drives home the importance of taking care of the entire body including oral health," explains Kenneth A. Krebs, DMD and AAP president. "In addition to this study about the relationship between CRP and pregnant women with periodontal disease, previous studies reported that inflammatory effects from periodontal disease could cause the liver to make proteins such as CRP that inflame arteries causing blood clots that contribute to heart attacks or strokes." Evidence supporting the association between periodontitis and CRP is based only on studies in men and non-pregnant women. This is the first study that looked at the association between CRP and periodontitis in pregnant women. The results of this study are consistent with previous studies conducted among men and non-pregnant women. CRP was higher in people with periodontal disease compared to those without disease. American Academy of Periodontology |
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| Related Periodontitis Current Events and Periodontitis News Articles Prevent periodontitis to reduce the risk of head and neck cancer Chronic periodontitis, a form of gum disease, is an independent risk factor for head and neck squamous cell carcinoma. This suggests the need for increased efforts to prevent and treat periodontitis as a possible means to reduce the risk of this form of cancer. Oral/Body Inflammatory Connection Explained Is your head where your heart is? It may be now. A strong connection between periodontal disease and cardiovascular disease (CVD) has been suggested in recent clinical studies. Patients with moderate to severe periodontitis need evaluation for heart disease risk Additional research is called for and patients with moderate to severe periodontitis should receive evaluation and possible treatment to reduce their risk of atherosclerotic cardiovascular disease (CVD). Over half of people with rheumatoid arthritis have periodontitis Over half (56%) of people with rheumatoid arthritis (RA) also have periodontitis (a chronic inflammatory disease of the gum and surrounding ligaments and bones that hold the teeth in place), displaying fewer teeth than healthy matched controls, high prevalence of oral sites presenting dental plaque and advanced attachment loss (the extent of periodontal support that has been destroyed around a tooth) (chi square p<0.05). Treating gum disease helps rheumatoid arthritis sufferers People, who suffer from gum disease and also have a severe form of rheumatoid arthritis, reduced their arthritic pain, number of swollen joints and the degree of morning stiffness when they cured their dental problems. Scientists find shared genetic link between the dental disease periodontitis and heart attack The relationship between the dental disease periodontitis and coronary heart disease (CHD) has been known for several years. Dental researchers ID new target in fight against osteoporosis, periodontitis Osteoporosis and periodontitis are common diseases whose sufferers must cope with weakness, injury and reduced function as they lose bone more quickly than it is formed. Examining TLR4 influences of B cell response Chronic inflammation, which is at the root of multiple diseases, links periodontal disease to increased incidence of cardiovascular disease. A healthy color About 80 percent of adults suffer from some form of periodontal, or gum disease, which can result in not just tooth loss, but has also been linked to heart disease, diabetes, blood infection, low birth-weight babies, cancer and most recently, obesity. Gene therapy effective treatment against gum disease Scientists at the University of Michigan have shown that gene therapy can be used to successfully stop the development of periodontal disease, the leading cause of tooth loss in adults. More Periodontitis Current Events and Periodontitis News Articles |
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