Researchers map links between size of hippocampus and progression to Alzheimer's dementiaMay 09, 2006FINDINGS: UCLA researchers sought to test the theory that the hippocampus - the area of the brain that processes memory - is smaller in patients with mild cognitive impairment who develop into Alzheimer's dementia, and that it is larger in patients with mild cognitive impairment who experience cognitive stability or improvement. Using novel 3-D mapping techniques to analyze MRI (magnetic resonance imaging) data from 20 patients with mild cognitive impairment, they found that the patients with the smaller hippocampus did, in fact, face an increased risk of developing dementia. IMPACT: The technique helps physicians detect subtle anatomical differences and can be applied to any disease affecting the hippocampus such as other forms of dementia, epilepsy, hippocampal sclerosis, etc. Tools such as this for predicting cognitive decline hold great promise for patient counseling, advanced planning and therapeutic decision-making. University of California-Los Angeles |
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| Related Hippocampus Current Events and Hippocampus News Articles New Down syndrome treatment suggested by Stanford/Packard study in mice At birth, children with Down syndrome aren't developmentally delayed. But as they age, these kids fall behind. Memory deficits inherent in Down syndrome hinder learning, making it hard for the brain to collect experiences needed for normal cognitive development. Cognitive dysfunction reversed in mouse model of Down syndrome A study by neuroscientist William C. Mobley, MD, PhD, chair of the Department of Neurosciences at the University of California, San Diego School of Medicine, and colleagues at Stanford University Medical School has demonstrated a possible new approach to slowing the inevitable progression of cognitive decline found in Down's syndrome. New neuroimaging analysis technique identifies impact of Alzheimer's disease gene in healthy brains Brain imaging can offer a window into risk for diseases such as Alzheimer's disease (AD). A study conducted at the University of Kansas School of Medicine demonstrated that genetic risk is expressed in the brains of even those who are healthy, but carry some risk for AD. Theory about long and short-term memory questioned by UCL scientists The long-held theory that our brains use different mechanisms for forming long-term and short-term memories has been challenged by new research from UCL, published today in PNAS. Weizmann Institute scientists reveal how some aromas are bound up in our memories From Proust's Madeleines to the overbearing food critic in the movie Ratatouille who's transported back to his childhood at the aroma of stew, artists have long been aware that some odors can spontaneously evoke strong memories. Estrogen therapy likely must be given soon after menopause to provide stroke protection For estrogen replacement to provide stroke protection, it likely must be given soon after levels drop because of menopause or surgical removal of the ovaries, scientists report in the Journal of Neuroscience. Aiming to avoid damage to neurocognitive areas of the brain during cranial radiation Radiation oncologists at Rush University Medical Center are intent on finding ways to avoid damage to the critically important hippocampus and limbic circuit of the brain when cranial radiation is required to treat existing or potential metastatic cancers. Fighting Sleep, Penn Researchers Reverse the Cognitive Impairment Caused By Sleep Deprivation A research collaboration led by biologists and neuroscientists at the University of Pennsylvania has found a molecular pathway in the brain that is the cause of cognitive impairment due to sleep deprivation. Why antidepressants don't work for so many More than half the people who take antidepressants for depression never get relief. Alzheimer's researchers find high protein diet shrinks brain One of the many reasons to pick a low-calorie, low-fat diet rich in vegetables, fruits, and fish is that a host of epidemiological studies have suggested that such a diet may delay the onset or slow the progression of Alzheimer's disease (AD). More Hippocampus Current Events and Hippocampus News Articles |
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