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Mass spectrometry methods database gets major update
May 26, 2006Researchers at the National Institute of Standards and Technology (NIST) recently added 150 new methods-nicknamed "recipes"-to a database already containing 255 procedures for analyzing specific synthetic polymers using matrix-assisted laser desorption/ionization (MALDI) mass spectrometry.
The recipes provide data critical to the industrial design, manufacture and application of synthetic polymers. They have been collected from the peer-review scientific literature and included in the NIST Synthetic Polymer MALDI Methods Online Database, http://www.nist.gov/maldi , a unique resource for the mass spectroscopy community.
National Institute of Standards and Technology (NIST)
Mass Spectrometry Current Events and Mass Spectrometry News RSSResearchers begin to decipher metabolism of sexual assault drug
It's a naturally occurring brain chemical with an unwieldy name: 4-hydroxybutyrate (4-HB). Taken by mouth, it can be abused or used as a date-rape drug.
Protein changes in heart strengthen link between Alzheimer's disease and chronic heart failure
A team of U.S., Canadian and Italian scientists led by researchers at Johns Hopkins report evidence from studies in animals and humans supporting a link between Alzheimer's disease and chronic heart failure, two of the 10 leading causes of death in the United States.
Tiny bubbles clean oil from water
Small amounts of oil leave a fluorescent sheen on polluted water. Oil sheen is hard to remove, even when the water is aerated with ozone or filtered through sand.
Engineers image nanostructure of a solid acid catalyst and boost its catalytic activity
The catalytic processes that facilitate the production of many chemicals and fuels could become much more environmentally friendly thanks to a breakthrough achieved by researchers from Lehigh and Rice Universities.
New imagining technique could lead to better antibiotics and cancer drugs
A recently devised method of imaging the chemical communication and warfare between microorganisms could lead to new antibiotics, antifungal, antiviral and anti-cancer drugs, said a Texas AgriLife Research scientist.
Scientists visualize how bacteria talk to one another
Using imaging mass spectrometry, researchers at the University of California, San Diego have developed tools that will enable scientists to visualize how different cell populations of cells communicate.
Super sticky barnacle glue cures like blood clots
Barnacles are a big problem for boats. Adhering to the undersides of vessels, carpets of the crustaceans can increase fuel consumption by as much as 25%.
How Proteins Talk to Each Other
Investigators at Burnham Institute for Medical Research (Burnham) have identified novel cleavage sites for the enzyme caspase-3 (an enzyme that proteolytically cleaves target proteins).
Drug discovery process more accurate, less expensive using novel mass spectrometry application
Cancer and cell biology experts at the University of Cincinnati (UC) have developed a new mass spectrometry-based tool they say provides more precise, cost-effective data collection for drug discovery efforts.
What makes stem cells tick?
Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) and their differentiated derivatives.
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Mass Spectrometry: Principles and Applications by Edmond de Hoffmann (Author), Vincent Stroobant (Author) The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives from the mass spectra. This new edition has been thoroughly revised and updated and has been redesigned to give the book a more contemporary look. As with previous editions it contains numerous... |
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Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation by J. Throck Watson (Author), O. David Sparkman (Author) Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references.
This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for... |
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Mass Spectrometry: A Textbook by Jürgen H. Gross (Author) This book is tailored for students and professionals as well as novices from other fields to mass spectrometry, an indispensable tool in chemistry and life sciences. It will guide them from the basics to the successful application of mass spectrometry in their daily research. Starting from the very principles of gas-phase ion chemistry and isotopic properties, it leads through the design of mass analyzers and ionization methods in use to mass spectral interpretation and coupling techniques. Step by step the readers will learn how mass spectrometry works and what it can do as a powerful tool in their hands. The book comprises a balanced mixture of practice-oriented information and theoretical background. The clear layout, a wealth of high-quality figures and a database of exercises... |
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Interpretation of Mass Spectra by Fred W. McLafferty (Author), Turecek (Author) Extensively revised and updated, this new edition, as in previous editions, emphasizes the point that the most important part of learning how to interpret unknown mass spectra is to practice interpreting mass spectra. The book aims at correlating ion dissociation mecanisms on a much broader scale, with the emphasis on basic attributes such as ionization energies, proton affinities and bond dissociation energies. The authors also tried to show how these mechanisms are applicable to the unimolecular dissociations of ions formed by any ionization method, including the new methods for obtaining mass spectra of large molecules. |
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The Expanding Role of Mass Spectrometry in Biotechnology, Second Edition by Gary Siuzdak (Author) Mass Spectrometry has become one of the most important tools in the biochemical sciences with capabilities ranging from small molecule analysis to protein characterization. Because of this versatility, mass spectrometry is the technology many scientists are turning to. The Expanding Role of Mass Spectrometry in Biotechnology covers the basic concepts in mass spectrometry as well as advanced topics including protein identification/protein structural analysis, carbohydrate and oligonucleotide analysis. Topics also include pharmacokinetics, high throughput screening, and the recent development of mass spectrometry in clinical diagnosis. Features: Abundant Illustrations Mass Spectrometry Basics Protein Identification/Characterization Carbohydrate/Oligonucleotide/Steroid Analysis... |
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Fundamentals of Contemporary Mass Spectrometry (Wiley - Interscience Series on Mass Spectrometry) by Chhabil Dass (Author) Modern mass spectrometry - the instrumentation and applications in diverse fields Mass spectrometry has played a pivotal role in a variety of scientific disciplines. Today it is an integral part of proteomics and drug discovery process. Fundamentals of Contemporary Mass Spectrometry gives readers a concise and authoritative overview of modern mass spectrometry instrumentation, techniques, and applications, including the latest developments. After an introduction to the history of mass spectrometry and the basic underlying concepts, it covers: Instrumentation, including modes of ionization, condensed phase ionization techniques, mass analysis and ion detection, tandem mass spectrometry, and hyphenated separation techniques Organic and inorganic mass spectrometry ... |
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Mass Spectrometry: Instrumentation, Interpretation, and Applications (Wiley - Interscience Series on Mass Spectrometry) by Dominic M. Desiderio (Author), Nico M. Nibbering (Author), Rolf Ekman (Editor), Jerzy Silberring (Editor), Ann M. Brinkmalm (Editor) With contributions from noted experts from Europe and North America, Mass Spectrometry Instrumentation, Interpretation, and Applications serves as a forum to introduce students to the whole world of mass spectrometry and to the many different perspectives that each scientific field brings to its use. The book emphasizes the use of this important analytical technique in many different fields, including applications for organic and inorganic chemistry, forensic science, biotechnology, and many other areas. After describing the history of mass spectrometry, the book moves on to discuss instrumentation, theory, and basic applications. |
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Mass Spectrometry of Proteins and Peptides: Methods and Protocols, Second Edition (Methods in Molecular Biology) by Mary S. Lipton (Editor), Ljiljana Pasa-Tolic (Editor) When the last edition of this book was published in 2000, the field of proteomics was in its infancy. Now in its adolescence, proteomics is fundamentally transforming biological and medical research. Much of this transformation can be attributed to technological advancements, particularly in mass spectrometry. As a result of these rapid developments that have led to expanded areas of research and innovative applications, an update to Mass Spectrometry of Proteins and Peptides is not only worthwhile, but arguably mandatory. Spanning fields from microbial forensics and clinical applications to protein structure, dynamics and function, the following chapters written by leading experts serve as a forum for presenting some of the latest revolutionizing methods for mass spectrometry-based... |
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Journal of the Mass Spectrometry Society of Japan by Maruzen Co Ltd | |
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Trace Quantitative Analysis by Mass Spectrometry by Robert K. Boyd (Author), Cecilia Basic (Author), Robert A. Bethem (Author) This book provides a serious introduction to the subject of mass spectrometry, providing the reader with the tools and information to be well prepared to perform such demanding work in a real-life laboratory. This essential tool bridges several subjects and many disciplines including pharmaceutical, environmental and biomedical analysis that are utilizing mass spectrometry: Covers all aspects of the use of mass spectrometry for quantitation purposes Written in textbook style to facilitate understanding of this topic Presents fundamentals and real-world examples in a ‘learning-though-doing’ style |
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