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Edinburgh researchers to probe memory loss in people with diabetics
June 27, 2006Researchers at the University of Edinburgh are aiming to pinpoint why diabetes can cause memory loss and mental decline. A thousand people will take part in the study, the largest of its kind ever undertaken in the UK.
The research team will ask people with Type 2 diabetes —associated with an increased risk of memory impairment and dementia —aged 60-75 years to complete puzzle-based tests and have their heart function and blood sugar levels measured. Follow up tests four years later will find out if there have been any changes in brain function.
Dr Mark Strachan, an honorary senior lecturer at the University and a consultant in diabetes and endocrinology at the Western General Hospital, said: "People with type 2 diabetes are at increased risk of developing problems with memory and problem-solving abilities. Although the cause of these abnormalities is not understood, various risk factors associated with diabetes may be important. For example, in some cases, high blood sugar levels can be damaging to small blood vessels in the eyes, nerves and kidneys and there is evidence that the same damage — microvascular disease — can occur in the brains of people with diabetes.
"The main aim of this study is to find out which risk factors, including microvascular disease, inflammation and alterations in hormone levels are linked to altered brain function in people with diabetes. This information is crucial in determining the cause of diabetes-related memory problems and other changes in brain function such as problem-solving abilities and attention span." He added: "Diabetes affects around three per cent of the UK population, and about 170,000 people in Scotland are known to be affected. The prevalence of diabetes is increasing but we are better at treating its complications, such as heart disease. As a result, people with diabetes are likely to live longer and so cognitive problems are likely to become a much bigger issue.\\\
University of Edinburgh
"The main aim of this study is to find out which risk factors, including microvascular disease, inflammation and alterations in hormone levels are linked to altered brain function in people with diabetes. This information is crucial in determining the cause of diabetes-related memory problems and other changes in brain function such as problem-solving abilities and attention span." He added: "Diabetes affects around three per cent of the UK population, and about 170,000 people in Scotland are known to be affected. The prevalence of diabetes is increasing but we are better at treating its complications, such as heart disease. As a result, people with diabetes are likely to live longer and so cognitive problems are likely to become a much bigger issue.\\\
University of Edinburgh
Diabetes Current Events and Diabetes News RSSESC to give talks on Diabetes in three cities in China
As a result of successful events organised last year, a second Joint Scientific Forum, organised by the European Society of Cardiology (ESC) and the European Association for the Study of Diabetes (EASD), two of the most respected professional medical organisations in Europe, will be held from 27-29 November at three venues across China - Beijing, Shanghai and Guangzhou.
New research shows versatility of amniotic fluid stem cells
For the first time, scientists have demonstrated that stem cells found in amniotic fluid meet an important test of potential to become specialized cell types, which suggests they may be useful for treating a wider array of diseases and conditions than scientists originally thought.
First reconstitution of an epidermis from human embryonic stem cells
Stem cell research is making great strides. This is yet again illustrated by a study carried out by the I-STEM* Institute (I-STEM/ Inserm UEVE U861/AFM), published in the Lancet on 21 November 2009. The I-STEM team, directed by Marc Peschanski has just succeeded in recreating a whole epidermis from human embryonic stem cells.
An atomic-level look at an HIV accomplice
Since the discovery in 2007 that a component of human semen called SEVI boosts infectivity of the virus that causes AIDS, researchers have been trying to learn more about SEVI and how it works, in hopes of thwarting its infection-promoting activity.
Scripps research scientists find new link between insulin and core body temperature
A team led by scientists at The Scripps Research Institute have discovered a direct link between insulin-a hormone long associated with metabolism and metabolic disorders such as diabetes-and core body temperature.
Scientists find molecular trigger that helps prevent aging and disease
Researchers at Mount Sinai School of Medicine set out to address a question that has been challenging scientists for years: How do dietary restriction-and the reverse, overconsumption-produce protective effects against aging and disease?
Pivotal study for PSD502 -- the first potential treatment for premature ejaculation
At the annual meeting of the Sexual Medicine Society of North America (SMSNA), Inc. in San Diego, Sciele Pharma, Inc., a Shionogi Company and Plethora Solutions Limited, a wholly owned subsidiary of Plethora Solutions Holdings PLC ("Plethora" - AIM:PLE)., today presented data from its second positive pivotal study of PSD502 for the treatment of premature ejaculation (PE).
Night Beat, Overtime and a Disrupted Sleep Pattern Can Harm Officers' Health
A police officer who works the night shift, typically from 8 p.m. to 4 a.m., already is at a disadvantage when it comes to getting a good "night's" sleep.
Fat collections linked to decreased heart function
Researchers from Boston University School of Medicine (BUSM) have shown that fat collection in different body locations, such as around the heart and the aorta and within the liver, are associated with certain decreased heart functions.
Thoughtful words help couples stay fighting fit
Couples who bring thoughtful words to a fight release lower amounts of stress-related proteins, suggesting that rational communication between partners can ease the impact of marital conflict on the immune system.
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