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Perth researchers to trial bird flu vaccine
June 29, 2006Perth researchers have begun a trial to test the effectiveness of a new vaccine to protect against the potentially deadly bird flu.
The Vaccine Trials Group at the Telethon Institute for Child Health Research and Princess Margaret Hospital for Children is recruiting 150 adult volunteers to participate in the study.
Study leader, Dr Peter Richmond, said the Australian-developed vaccine has shown encouraging results in early trials.
"While there hasn't been any case of bird flu being spread from human to human, it's important that we're not complacent, and keep working to find ways to protect our community from a possible pandemic," Dr Richmond said.
"The best preparation is to have a vaccine available that is proven to be safe and effective—and that's our aim."
Dr Richmond said there was no live virus in the vaccine which meant there was no chance of catching the infection from the vaccination. He said the vaccine had already been shown to be safe in initial trials.
"What this study is most interested in determining is just how much of the vaccine is needed to provide good protection against bird flu," Dr Richmond said.
"In the initial trial a small dose of the vaccine generated a good immune response in about half of the participants.
"In this trial we will increase the dosage to see if that promotes good immunity in a larger proportion of participants, but even with the increase, the total amount of vaccine is still the same as what would be found in conventional flu vaccines.\\\
Research Australia
"While there hasn't been any case of bird flu being spread from human to human, it's important that we're not complacent, and keep working to find ways to protect our community from a possible pandemic," Dr Richmond said.
"The best preparation is to have a vaccine available that is proven to be safe and effective—and that's our aim."
Dr Richmond said there was no live virus in the vaccine which meant there was no chance of catching the infection from the vaccination. He said the vaccine had already been shown to be safe in initial trials.
"What this study is most interested in determining is just how much of the vaccine is needed to provide good protection against bird flu," Dr Richmond said.
"In the initial trial a small dose of the vaccine generated a good immune response in about half of the participants.
"In this trial we will increase the dosage to see if that promotes good immunity in a larger proportion of participants, but even with the increase, the total amount of vaccine is still the same as what would be found in conventional flu vaccines.\\\
Research Australia
Scientist warns over pandemic flu vaccine 6-month time lag
New research published today (Monday April 27) from the University of Leicester and University Hospitals of Leicester NHS Trust warns of a six-month time lag before effective vaccines can be manufactured in the event of a pandemic flu outbreak.
New vaccine may give long-term defense against deadly bird flu and its variant forms
A new vaccine under development may provide protection against highly pathogenic bird flu and its evolving forms, according to researchers at Purdue University and the Centers for Disease Control and Prevention who discovered the new preventative drug and have tested it in mice.
Duke To Test Bird Flu Vaccine Dosing
A clinical trial to test different strengths of a vaccine designed to fight avian influenza will begin this month at Duke University Medical Center.
Bird-flu vaccine works at high doses; Focus turns to ways to stretch vaccine supply
An experimental vaccine against bird flu is safe and spurs the immune response considered necessary to protect against the deadly illness, at a dose several times larger than the traditional flu shot and in slightly more than half of people who received the largest dose.
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