Science Current Events | Science News | Brightsurf.com
 
Email a Friend Send to a friend
Printer Friendly Print Venous thrombosis after travel

Venous thrombosis after travel

August 22, 2006

Several types of travel increase risk of venous thrombosis

Traveling for more than 4 hours by air, car, bus or train is associated with an increased risk of venous thrombosis. In a large study (the MEGA study) of nearly 2000 people with a first thrombosis in the Netherlands, Dr Suzanne Cannegieter and colleagues from the Leiden University Medical Center looked at the risk factors for thrombosis compared with their partners, who did not have thrombosis. The results, published in the international open-access medical journal PLoS Medicine, showed that 233 of the people with thrombosis had traveled for more than 4 h in the 8 weeks preceding the event. Although the overall risk of developing thrombosis is still low, traveling in general was found to increase the risk of venous thrombosis 2-fold. The risk was highest in the first week after traveling, and the overall risk of flying was largely similar to the risks of traveling by car, bus, or train.




In particular groups of people the risk was increased. For example, the risk was up to 8-fold in people who also had a specific mutation in one of the genes involved in clotting (factor V Leiden); almost 10-fold in those who had a body mass index of more than 30 kg/m2; 4-fold in those who were more than 1.90 m tall; and more than 20-fold in those who used oral contraceptives. For air travel these findings of risk in particular groups were more apparent than for other modes of travel, and in addition, people shorter than 1.60 m had an almost 5-fold risk of thrombosis after air travel. However, the numbers of people in each of these groups was small and hence the estimates of risk must be interpreted carefully.

The authors conclude that the risk of venous thrombosis is moderately increased for all these modes of travel, and that in particular groups of people the risk is highly increased. The study could not show the mechanism of the increased risk, although the association of thrombosis with all types of travel, not just air travel, suggests that immobility is a key factor. Other mechanisms, such as reduced oxygen levels triggering clotting, may be involved in the particularly increased risk seen in air travel in some groups.

For those who have an increased risk, such as oral contraceptive users and individuals with factor V Leiden, the authors say that preventative measure such as exercises may be warranted. However, the study's results apply only to people younger than 70 y of age and it is likely that other characteristics exist that also increase the risk. These characteristics are being investigated in an ongoing study - the World Health Organization Research Initiative into the Global Hazards of Travel (WRIGHT).

Public Library of Science



Related Venous Thrombosis Current Events and Venous Thrombosis News Articles Venous Thrombosis Current Events and Venous Thrombosis News RSS Venous Thrombosis Current Events and Venous Thrombosis News RSS
Clots traveling from lower veins may not be the cause of pulmonary embolism in trauma patients
A report from a team of Massachusetts General Hospital (MGH) physicians calls into question the longstanding belief that pulmonary embolism (PE) - the life-threatening blockage of a major blood vessel in the lungs - is caused in trauma patients by a blood clot traveling from vessels deep within the legs or lower torso.

Blood clots in lungs might not always originate in deep veins of legs and pelvis in trauma patients
Few trauma patients who develop potentially deadly blood clots in the lungs (pulmonary embolism) also have clots in the deep veins of their pelvis and legs (deep venous thrombosis), challenging commonly held beliefs about the association between the two conditions.

Image-guided treatment for deep venous thrombosis could improve patients' long-term outcomes
Deep Venous Thrombosis (DVT) is a serious condition that involves the formation of a blood clot inside of a deep vein usually in the legs. A patient with DVT is typically treated with anticoagulants (blood thinners) however researchers have found that image-guided interventional radiology procedures may play a more central role in the long-term treatment of DVT.

Study explains potential failure of oral contraceptives with obese women
Researchers have identified a potential biological mechanism that could explain why oral contraceptives may be less effective at preventing pregnancy in obese women, as some epidemiological studies have indicated.

ESC reaffirms advice on cardiovascular risks associated with long-haul flights
Dr Steen Kristensen, Vice-president of the ESC, says: "Long distance flying is associated with an increase in deep venous thrombosis, which in some cases may lead to clotting of the lungs. People who are immobile, pregnant, taking contraceptive pills or have had venous thrombosis in the past are particularly at risk.

Research highlights new approaches to prevent blood clots
Blood clotting, or coagulation, is an important process that prevents excessive bleeding when a blood vessel is injured.

Thrombosis patients face greater risks than previously believed
Deep venous thrombosis (DVT), the formation of blood clots in the lower limbs, is the third-most common vascular disease in North America after heart attack and stroke, and is a frequent complication in hospitalized patients.

The risk factors of abdominal venous thrombosis
Abdominal venous thrombosis may present as BCS or SVT. Hereditary and acquired risk factors have been implicated in the etiopathogenesis of abdominal venous thrombosis

AJN study reveals compression stockings incorrectly used in 29 percent of patients
An original study, published in the September issue of the American Journal of Nursing (AJN), revealed that graduated compression stockings were used incorrectly in 29% of the patients and sized incorrectly in 26% of the patients.

Study finds it pays to be heart smart if considering hormone therapy
A research study has found that a simple blood test may indicate whether post-menopausal hormone therapies present an elevated risk of a heart attack.
More Venous Thrombosis Current Events and Venous Thrombosis News Articles
The Aetiology of Deep Venous Thrombosis: A Critical, Historical and Epistemological Survey

The Aetiology of Deep Venous Thrombosis: A Critical, Historical and Epistemological Survey
by P. Colm Malone (Author), Paul S. Agutter (Author)

What we now call deep venous thrombosis (DVT) has been elucidated by a diversity of investigative approaches during the past four centuries. The authors of this book survey the history of the field and ask: why has one of these perspectives the haematological/biochemical come to dominate research into the causation of DVT during the past 50 years and to exclude alternatives? In answering this question, they show that the current consensus model is conceptually flawed. Building on the work of William Harvey, John Hunter, Rudolf Virchow, Ludwig Aschoff and a number of pathologists in the mid-20th century, they offer a revised account of the aetiology of this condition. In the process they retrace and review the 160-year-old philosophical and methodological schism in biomedical research...

PlexiPulse Foot Compression Therapy Wraps, Pair

PlexiPulse Foot Compression Therapy Wraps, Pair
by KCI

For use only with the PlexiPulse Foot Compression Therapy Pump. Sold only in pairs. DOES NOT INCLUDE PUMP. PUMP SOLD SEPARATELY UNDER ITEM NUMBER B00169JZJ6.

Handbook on Cerebral Venous Thrombosis (Frontiers of Neurology and Neuroscience)

Handbook on Cerebral Venous Thrombosis (Frontiers of Neurology and Neuroscience)
by V. Caso (Editor), G Agnelli (Editor), M. Paciaroni (Editor)

Cerebral veins contain about 70 per cent of the total cerebral blood volume, but cerebral venous thrombosis (CVT) occurs about a thousand times less often than arterial stroke. CVT affects mostly young adults and children, and in about one quarter of cases the cause remains unknown. Written by international experts, this publication is dealing with epidemiology, risk factors, coagulation disorders, clinical presentation - especially focusing on headache, current neuroradiological treatment, complications and long-term prognosis of CVT. The book covers the full spectrum of CVT pathogenesis and offers a new and effective approach to improve earlier diagnosis, recognize new risk factors and to identify the most severe manifestations, which require more aggressive treatments.Neurologists,...

  Pro & Con: Do third-generation oral contraceptives carry a higher risk of venous thrombosis than second-generation pills?: An article from: Internal Medicine News
by International Medical News Group (Publisher)

This digital document is an article from Internal Medicine News, published by International Medical News Group on November 15, 2001. The length of the article is 702 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Pro & Con: Do third-generation oral contraceptives carry a higher risk of venous thrombosis than second-generation pills?
Publication: Internal Medicine News (Magazine/Journal)
Date: November 15, 2001
Publisher: International Medical News Group
Volume: 34 Issue: 22 Page: 6(1)

Distributed by Thomson...

  Venous thrombosis and pulmonary embolism (Mt. Sinai Hospital monograph)
by Harold Neuhof (Author)



  Orgaran Extending the Frontiers of Venous Thrombosis Prophylaxis (Haemostasis)
by J. Hirsh (Editor)

Orgaran, composed of heparan, dermatan and chondroitin sulfates, is a new antithrombotic agent which shows great therapeutic potential. This proceedings issue discusses Orgaran's pharmacological mechanisms and presents pre-clinical trials as well as clinical trials in patients with heparin-induced thrombocytopenia and patients having hip surgery. In these studies, Orgaran is compared to either placebo or standard low-dose heparin. Results indicate that Orgaran has a particularly long biological half-life and produces less bleeding than heparin or an equivalent anti-thrombotic effect.

  Venous thrombosis during myocardial insufficiency. by F. J. Slad
by Sladen. Frank Joseph. 1882- (Author)



  Malignancy and Venous Thrombosis. 2005 Edition
by Jeanette W. Blom (Author)



Handbook of Deep Venous Thrombosis

Handbook of Deep Venous Thrombosis
by T. M. Hyers (Author)



  Do third-generation OCs carry a higher risk of venous thrombosis than second-generation OCs? (Pro & Con).(oral contraceptives)(Brief Article): An article from: Family Practice News
by International Medical News Group (Publisher)

This digital document is an article from Family Practice News, published by International Medical News Group on January 15, 2002. The length of the article is 733 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Do third-generation OCs carry a higher risk of venous thrombosis than second-generation OCs? (Pro & Con).(oral contraceptives)(Brief Article)
Publication: Family Practice News (Magazine/Journal)
Date: January 15, 2002
Publisher: International Medical News Group
Volume: 32 Issue: 2 Page: 10(1)

Article Type: Brief Article

Distributed by Thomson...

© 2009 BrightSurf.com