 |
|
Drug could change the standard treatment during procedures to clear blocked arteries
September 11, 2006A study led by a University of Kentucky researcher being published in the country's leading medical journal could one day change the standard treatment for preventing blood clots during procedures to open up blocked arteries feeding the heart.
Dr. Steven Steinhubl, co-chairman and senior author of a study appearing in the current issue of the New England Journal of Medicine, said the drug used in the study, enoxaparin, has the potential to become a standard treatment in stent and angioplasty procedures, but more research is necessary to come to a definitive conclusion. The current standard of care is to give patients unfractionated heparin.
Steinhubl, an interventional cardiologist and researcher at UK's Linda and Jack Gill Heart Institute, said that while elective stent and angioplasty procedures to clear blocked arteries are generally safe, a small percentage of patients will experience significant bleeding due to the procedure that can increase the cost and duration of the hospital stay and, in rare instances, even cause death.
In the study, researchers examined enoxaparin to determine if it is a safe and effective anti-clotting drug, carrying less risk for bleeding following the procedure than unfractionated heparin.
The study found that major bleeding was cut by more than half in patients receiving enoxaparin. It also showed that doctors were much more likely to achieve the targeted level of blood thinning for their patients with enoxaparin compared with unfractionated heparin.
"Bleeding following a stent placement or angioplasty is an event that is not only dangerous for patients, but also carries a financial burden for the health care industry as a whole," Steinhubl said. "Millions of these procedures are successfully performed at hospitals across the United States each year. It is important that we make what has become a relatively safe procedure even safer by finding a drug that will effectively prevent blood clots and not put patients at risk for unnecessary bleeding. This study, which was designed to test the safety of enoxaparin, is one of the first steps we as cardiologists are taking to reach that goal."
University of Kentucky
In the study, researchers examined enoxaparin to determine if it is a safe and effective anti-clotting drug, carrying less risk for bleeding following the procedure than unfractionated heparin.
The study found that major bleeding was cut by more than half in patients receiving enoxaparin. It also showed that doctors were much more likely to achieve the targeted level of blood thinning for their patients with enoxaparin compared with unfractionated heparin.
"Bleeding following a stent placement or angioplasty is an event that is not only dangerous for patients, but also carries a financial burden for the health care industry as a whole," Steinhubl said. "Millions of these procedures are successfully performed at hospitals across the United States each year. It is important that we make what has become a relatively safe procedure even safer by finding a drug that will effectively prevent blood clots and not put patients at risk for unnecessary bleeding. This study, which was designed to test the safety of enoxaparin, is one of the first steps we as cardiologists are taking to reach that goal."
University of Kentucky
Blocked Arteries Current Events and Blocked Arteries News RSSYour Own Stem Cells Can Treat Heart Disease
The largest national stem cell study for heart disease showed the first evidence that transplanting a potent form of adult stem cells into the heart muscle of subjects with severe angina results in less pain and an improved ability to walk. The transplant subjects also experienced fewer deaths than those who didn't receive stem cells.
Higher carotid arterial stenting rates associated with poorer clinical outcomes
Among eligible Medicare beneficiaries, increased use of carotid arterial stenting (CAS) procedures to treat carotid stenosis-the narrowing of the carotid artery-is associated with higher rates of mortality and adverse clinical outcomes, including heart attack and stroke, according to researchers from the University of Pennsylvania School of Medicine.
Two treatment innovations improve heart function after heart attack
Supersaturated oxygen (SSO2) administered during catheter-based treatments for heart attack can significantly reduce heart muscle damage, according to a new study reported in Circulation: Cardiovascular Interventions, a journal of the American Heart Association.
Oxygen-saturated blood reduces levels of damaged heart tissue following a heart attack
Results of a clinical trial published today in Circulation: Cardiovascular Interventions demonstrate that an infusion of blood that is "supersaturated" with oxygen (SS02) can reduce the amount of damaged heart muscle immediately following a life-threatening heart attack.
New drug may reduce heart attack damage
A new drug that targets a master disease-causing gene can dramatically reduce heart muscle damage after a heart attack and may lead to significantly improved patient outcomes, UNSW researchers have shown.
Death rates same for diabetes and heart disease patients receiving drug therapy or surgery
There is no difference in mortality among patients with type 2 diabetes and stable heart disease who received prompt bypass surgery or angioplasty compared to drug therapy alone, according to a landmark study focused exclusively on patients with both conditions.
Women with chest pain less likely then men to get proper treatment from paramedics
Women with chest pain are less likely than male patients to receive recommended, proven therapies while en route to the hospital.
Arrythmia associated with heart attacks linked to higher risk of death
Heart attack patients who develop serious arrhythmia in connection with procedures to open blocked arteries face a significantly higher risk of death for several months after the procedure, when compared to similar patients who do not develop such complications, according to new research from Duke University Medical Center.
Study proves that practice makes perfect in PCI for heart attack
When it comes to treating heart attacks, experience matters. New research shows that patients have a much better chance of survival when both their hospital and their physician have a strong track record in treating heart attack with angioplasty and stenting.
'Smart scaffolds' may help heal broken hearts
Imagine new treatments for heart disease or muscle loss that direct the body to repair damaged tissue rather than helping it cope with a weakened condition.
More Blocked Arteries Current Events and Blocked Arteries News Articles
|
I-5's blocked arteries.(Editorials)(Weight limits make bridge problem urgent)(Editorial): An article from: The Register-Guard (Eugene, OR) by The Register Guard (Publisher) This digital document is an article from The Register-Guard (Eugene, OR), published by The Register Guard on February 22, 2003. The length of the article is 817 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: I-5's blocked arteries.(Editorials)(Weight limits make bridge problem urgent)(Editorial) Publication: The Register-Guard (Eugene, OR) (Newspaper) Date: February 22, 2003 Publisher: The Register Guard Page: A16 Article Type: Editorial Distributed by Thomson... | |
|
Blocked arteries.(Editorials)(Storm reveals the fragility of transportation links)(Editorial): An article from: The Register-Guard (Eugene, OR) by Gale Reference Team (Author) This digital document is an article from The Register-Guard (Eugene, OR), published by Thomson Gale on December 7, 2007. The length of the article is 462 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Blocked arteries.(Editorials)(Storm reveals the fragility of transportation links)(Editorial) Author: Gale Reference Team Publication: The Register-Guard (Eugene, OR) (Newspaper) Date: December 7, 2007 Publisher: Thomson Gale Page: A12 Article Type: Editorial Distributed by Thomson... | |
|
Weighing the risks and benefits of reopening blocked arteries: FDA warns of blood clot risks with stents, and a study says angioplasty must be done quickly ... An article from: Women's Health Advisor by Gale Reference Team (Author) This digital document is an article from Women's Health Advisor, published by Thomson Gale on March 1, 2007. The length of the article is 864 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Weighing the risks and benefits of reopening blocked arteries: FDA warns of blood clot risks with stents, and a study says angioplasty must be done quickly to be beneficial.(CARDIOVASCULAR HEALTH) Author: Gale Reference Team Publication: Women's Health Advisor (Magazine/Journal) Date: March 1, 2007 Publisher: Thomson Gale Volume: 10 Issue: 3 Page: 3(1) Distributed by... | |
|
NEW MINIMALLY INVASIVE SYSTEM OPENS BLOCKED NECK ARTERIES.: An article from: Biotech Equipment Update by Worldwide Videotex (Publisher) This digital document is an article from Biotech Equipment Update, published by Worldwide Videotex on November 1, 2004. The length of the article is 610 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: NEW MINIMALLY INVASIVE SYSTEM OPENS BLOCKED NECK ARTERIES. Publication: Biotech Equipment Update (Newsletter) Date: November 1, 2004 Publisher: Worldwide Videotex Volume: 12 Issue: 11 Page: NA Distributed by Thomson... | |
|
Which option is best to reopen blocked coronary arteries? Studies suggest surgery may top angioplasty and stenting for severe heart disease, but the right ... An article from: Men's Health Advisor by Unavailable (Author) This digital document is an article from Men's Health Advisor, published by Belvoir Media Group, LLC on July 1, 2009. The length of the article is 1144 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available immediately after purchase. You can view it with any web browser. Citation Details Title: Which option is best to reopen blocked coronary arteries? Studies suggest surgery may top angioplasty and stenting for severe heart disease, but the right choice depends on your individual condition.(Cardiovascular health)(Clinical report) Author: Unavailable Publication: Men's Health Advisor (Magazine/Journal) Date: July 1, 2009 Publisher: Belvoir Media Group, LLC Volume: 11 Issue: 7 Page:... | |
|
NON-SURGICAL CRYOPLASTY PROMISING FOR BLOCKED LEG ARTERIES.: An article from: Biotech Equipment Update by Worldwide Videotex (Publisher) This digital document is an article from Biotech Equipment Update, published by Worldwide Videotex on April 1, 2005. The length of the article is 868 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: NON-SURGICAL CRYOPLASTY PROMISING FOR BLOCKED LEG ARTERIES. Publication: Biotech Equipment Update (Newsletter) Date: April 1, 2005 Publisher: Worldwide Videotex Volume: 13 Issue: 4 Page: NA Distributed by Thomson Gale | |
 |
Everything Low Cholesterol Book by Shirley Archer (Author) Your guide to preventing heart disease and living longer |
| © 2009 BrightSurf.com |