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Computer-aided detection could help breast cancer screening
September 27, 2006A novel approach to reading mammograms with the help of a computer could free up hundreds of medical man-hours, as well as speeding-up the breast screening process.
Scientists at The Universities of Manchester and Aberdeen and Cancer Research UK have found that the workload of radiologists could potentially be halved by using a new computer-aided system to help read breast x-rays and detect cancer.
With the computer-aided detection (CAD) system, only one expert is needed to look at each mammogram, rather than the usual two. Use of the system could free up the experts' time, enabling more face-to-face consultations and all women to be screened as often as recommended.
The CAD programme searches mammograms for suspicious features or irregularities that could be caused by cancer. When the computer finds anything unusual it indicates it on a screen for the radiologist to look at.
Study results published today show that mammogram readings by a single expert plus the CAD system may be as good as those read by two expert radiologists, and in some cases the new combination could be even more successful.
The researchers took more than 10 000 mammograms that had previously each been read by two radiologists. These were then read again by a single radiologist, who was prompted by the computer to double-check suspicious areas for any abnormalities.
The results showed that the cancer detection rate by a single reader using CAD was at least as good as that when the films were originally read by two readers.
The mammograms studied were from 1996, so that all cancers that developed subsequently in the group of women could be included, and no action was taken as a result of the radiologists' decisions.
Dr Caroline Boggis, Consultant Radiologist at the Nightingale Breast Centre in Manchester said: "The results of this first trial are very encouraging, and we have just started a new study to confirm that the results of using CAD are still as good when used in real decision-making in the breast screening programme."
This new trial will involve 30,000 women in Manchester, Coventry and Nottingham. Most of the women will have the single reading with CAD in addition to their routine double-reading. Radiographers and radiologists have been fully trained to use the CAD system, and a second opinion will always be available if they are any uncertainties.
Dr Boggis added, "Women in Greater Manchester currently being invited for their regular breast screening are being asked to participate in the new study, CADET (Computer-Aided Detection Evaluation Trial) 2, and we really hope that they will take part."
Dr Sue Astley of Manchester University Medical School continued: "This is an opportunity for women across the region to have their mammograms read using the latest CAD technology, which is already available in America and some European countries.
"The workload associated with mammography is extremely high, with double-reading taking place on around 1000 mammograms each week in Manchester. If we are able to confirm the promising results of the first study, using CAD could significantly help manpower problems in the breast screening service.\\\
University of Manchester
The CAD programme searches mammograms for suspicious features or irregularities that could be caused by cancer. When the computer finds anything unusual it indicates it on a screen for the radiologist to look at.
Study results published today show that mammogram readings by a single expert plus the CAD system may be as good as those read by two expert radiologists, and in some cases the new combination could be even more successful.
The researchers took more than 10 000 mammograms that had previously each been read by two radiologists. These were then read again by a single radiologist, who was prompted by the computer to double-check suspicious areas for any abnormalities.
The results showed that the cancer detection rate by a single reader using CAD was at least as good as that when the films were originally read by two readers.
The mammograms studied were from 1996, so that all cancers that developed subsequently in the group of women could be included, and no action was taken as a result of the radiologists' decisions.
Dr Caroline Boggis, Consultant Radiologist at the Nightingale Breast Centre in Manchester said: "The results of this first trial are very encouraging, and we have just started a new study to confirm that the results of using CAD are still as good when used in real decision-making in the breast screening programme."
This new trial will involve 30,000 women in Manchester, Coventry and Nottingham. Most of the women will have the single reading with CAD in addition to their routine double-reading. Radiographers and radiologists have been fully trained to use the CAD system, and a second opinion will always be available if they are any uncertainties.
Dr Boggis added, "Women in Greater Manchester currently being invited for their regular breast screening are being asked to participate in the new study, CADET (Computer-Aided Detection Evaluation Trial) 2, and we really hope that they will take part."
Dr Sue Astley of Manchester University Medical School continued: "This is an opportunity for women across the region to have their mammograms read using the latest CAD technology, which is already available in America and some European countries.
"The workload associated with mammography is extremely high, with double-reading taking place on around 1000 mammograms each week in Manchester. If we are able to confirm the promising results of the first study, using CAD could significantly help manpower problems in the breast screening service.\\\
University of Manchester
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The use of postmenopausal hormone therapy has decreased over time in the United States, which researchers suggest may play a key role in the declining rate of atypical ductal hyperplasia, a known risk factor for breast cancer.
Researcher: 'Optical biopsy' for breast cancer increasingly accurate
But women may not have to endure the medical costs, stress and potential complications that accompany such invasive biopsies forever. A University of Florida biomedical engineering researcher is making progress on an "optical biopsy" that has the potential to determine whether growths are cancerous without ever puncturing the skin.
M. D. Anderson redefines screening guidelines for breast, cervical and colorectal cancers
Drawing on years of experience in cancer research and patient care, The University of Texas M. D. Anderson Cancer Center released today the most comprehensive, risk-based screening guidelines publicly available to date for breast, cervical and colorectal cancers.
Study finds delay in follow-up among African-American women receiving abnormal breast finding
A new analysis has identified a significant delay in follow-up times among African-American women after the finding of a suspicious breast abnormality.
Researchers fine-tune Diffuse Optical Tomography for breast cancer screening
Clemson University researchers in collaboration with researchers at the University of Bremen, Germany, are working to make the physical pain and discomfort of mammograms a thing of the past, while allowing for diagnostic imaging eventually to be done in a home setting.
Researchers believe hormone therapy should not be stopped prior to mammograms
Researchers from Boston University School of Medicine (BUSM) are recommending that menopausal women on hormone therapy (HT) continue their treatment prior to having their annual mammogram screenings.
Researchers develop new, more-sensitive assay for detecting DNA methylation in colon cancer
A study published in this week's online issue of Nature Biotechnology, demonstrates a unique and highly sensitive method for detecting methylation-associated cancers.
Cancers set to 'explode' in Latino/a populations, expert says
he Latino/a population in the United States is expected to triple by 2050, according to projections from the U.S. Census Bureau. And along with that growth, says University of Illinois professor Lydia Buki, will come a rise in the number of individuals from that population who are diagnosed with cancer.
Reminder program dramatically increases mammography rates, Kaiser Permanente study finds
A reminder program aimed at screening for breast cancer when it is most treatable boosted mammography rates by more than 17 percentage points.
I-SPY trial offers key insights into locally advanced breast cancer
Scientists are reporting two findings that could influence the way researchers screen for, treat and assess prognosis for women with locally advanced breast cancer, an aggressive form of the disease.
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