Science Current Events | Science News | Brightsurf.com
 
Email a Friend Send to a friend
Printer Friendly Print Few clues about African ancestry to be found in mitochondrial DNA

Few clues about African ancestry to be found in mitochondrial DNA

October 12, 2006

Mitochondrial DNA may not hold the key to your origins after all. A study published today in the open access journal BMC Biology reveals that fewer than 10% of African American mitochondrial DNA sequences analysed can be matched to mitochondrial DNA from one single African ethnic group. There has been a growing interest in the use of mitochondrial DNA to trace maternal ancestries, and several companies now offer to analyse individuals' mitochondrial DNA sequences to obtain information about their origins. The current study suggests that only one in nine African Americans may be able to find clues about where their ancestors came from, in their mitochondrial DNA.

Bert Ely, from the University of North Carolina, and colleagues from other Universities in the USA analysed a database of the human variable region, or HVS-1 region, of mitochondrial (mt) DNA sequences from sub-Saharan Africa. They then compared two samples of African American mt DNA sequences to the database, to identify exact matches to the sub-Saharan sequences.




Ely et al.'s results show that more than half of the African American HSV-1 sequences were found in many different sub-Saharan ethnic groups. Forty percent of the African American HSV-1 sequences did not match any sequences in the database and fewer than 10% were an exact match to a sequence from a single African ethnic group.

BioMed Central



Related Mitochondrial Dna Current Events and Mitochondrial Dna News Articles Mitochondrial Dna Current Events and Mitochondrial Dna News RSS Mitochondrial Dna Current Events and Mitochondrial Dna News RSS
Unknowlingly consuming endangered tuna
While most of us would never willingly consume a highly endangered species, doing so might be as easy as plucking sushi from a bento box.

Tags reveal white sharks have neighborhoods in the north Pacific, say Stanford researchers
The white shark may be the ultimate loner of the ocean, cruising thousands of miles in a solitary trek, but a team of researchers has discovered that the sharks have maintained such a consistent pattern of migration that over tens of thousands of years the white sharks in the northeastern Pacific Ocean have separated themselves into a population genetically distinct from sharks elsewhere in the world.

The first men and women from the Canary Islands were Berbers
A team of Spanish and Portuguese researchers has carried out molecular genetic analysis of the Y chromosome (transmitted only by males) of the aboriginal population of the Canary Islands to determine their origin and the extent to which they have survived in the current population.

Whale-sized genetic study largest ever for southern hemisphere humpbacks
After 15 years of research in the waters of the South Atlantic and Indian Oceans, scientists from the Wildlife Conservation Society, the American Museum of Natural History, and an international coalition of organizations have unveiled the largest genetic study of humpback whale populations ever conducted in the Southern Hemisphere.

Barcoding endangered sea turtles
Conservation geneticists who study sea turtles have a new tool to help track this highly migratory and endangered group of marine animals: DNA barcodes.

Dog's place and date of birth identified
Earlier studies of this field have shown that Eastern Asia is the place where the wolf was tamed to become the dog.

Discovery of genetic mutation in Leigh syndrome
Researchers at the Montreal Neurological Institute and Hospital (The Neuro), McGill University have discovered a genetic mutation underlying late-onset Leigh syndrome, a rare inherited metabolic disorder characterized by the degeneration of the central nervous system.

New insect on Balearic Islands
After 10 years of biochemical and molecular analysis of the Tyrrhenoleuctra plecoptera that live in the Western Mediterranean, Spanish and Italian scientists have now demonstrated that one of the insect populations of this group is a distinct and, therefore, new species.

Neurological disorder in golden retriever dogs caused by a mutation in mitochondrial DNA
Sensory ataxic neuropathy (SAN) is a recently identified neurological disorder in Golden Retriever dogs with onset during puppyhood.

Mysterious disappearance of explorer Everett Ruess solved after 75 years
The mysterious disappearance of Everett Ruess, a 20-year-old artist, writer and footloose explorer who wandered the Southwest in the early 1930s on a burro and who has become a folk hero to many, has been solved with the help of University of Colorado at Boulder researchers and the National Geographic Society.
More Mitochondrial Dna Current Events and Mitochondrial Dna News Articles
Human Mitochondrial DNA and the Evolution of Homo sapiens (Nucleic Acids and Molecular Biology)

Human Mitochondrial DNA and the Evolution of Homo sapiens (Nucleic Acids and Molecular Biology)
by Hans-Jürgen Bandelt (Editor), Martin Richards (Editor), Vincent Macaulay (Editor)

Mitochondrial DNA is one of the most explored genetic systems because of what it can tell us about the human past. This volume takes a unique perspective, presenting the disparate strands that must be tied together to exploit this system. From molecular biology to anthropology, statistics to ancient DNA, this first volume of three presents the global picture of human mitochondrial DNA variation. It takes a critical look at the field, flagging the problems, as well as the successes, and always placing the mitochondrial phylogeny centre stage.

60 Minutes - Roots (October 7, 2007)

60 Minutes - Roots (October 7, 2007)

Airdate: 10/07/07 Marion West, a Missouri rancher, and Vy Higginsen, a New York City gospel director, never knew they were related until a blood test traced their ancestry back generations and found a common caucasian relative. The problem is, similar tests also told Vy she had ancestors in numerous African tribes and various countries. Lesley Stahl reports on this new field of genetic genealogy, which some say promises its customers more than it can deliver.

This product is manufactured on demand using DVD-R recordable media. Amazon.com's standard return policy will apply.

Mitochondrial DNA: Methods and Protocols (Methods in Molecular Biology)

Mitochondrial DNA: Methods and Protocols (Methods in Molecular Biology)
by Jeffrey A. Stuart (Editor)

Since the publication of the first edition, the number of unique heritable mtDNA mutations recognized as being associated with bioenergetic dysfunction, cell death and disease has grown. Likewise, our understanding of the basic biology of somatic mtDNA mutations continues to improve. In Mitochondrial DNA: Methods and Protocols, Second Edition, specialists from eight countries share their expertise, providing detailed protocols for studying many aspects of mtDNA. The volume is divided into three sections, which cover the transduction of information from mtDNA to functionally active respiratory complexes, mitochondrial reactive oxygen species (ROS) production as well as mtDNA damage and its repair, and the identification and quantification of heteroplasmic mtDNA mutations. Written in the...

The Seven Daughters of Eve: The Science That Reveals Our Genetic Ancestry

The Seven Daughters of Eve: The Science That Reveals Our Genetic Ancestry
by Bryan Sykes (Author)

The national bestseller that reveals how we are descended from seven prehistoric women. One of the most dramatic stories of genetic discovery since James Watson's The Double Helix, The Seven Daughters of Eve reveals the remarkable story behind a groundbreaking scientific discovery. After being summoned in 1997 to an archaeological site to examine the remains of a five-thousand-year-old man, Bryan Sykes ultimately was able to prove not only that the man was a European but also that he has living relatives in England today. In this lucid, absorbing account, Sykes reveals how the identification of a particular strand of DNA that passes unbroken through the maternal line allows scientists to trace our genetic makeup all the way back to prehistoric times, to seven primeval women, the Seven...

The Genetic Strand: Exploring a Family History Through DNA

The Genetic Strand: Exploring a Family History Through DNA
by Edward Ball (Author)

The Genetic Strand is the story of a writer's investigation, using DNA science, into the tale of his family's origins. National Book Award winner Edward Ball has turned his probing gaze on the microcosm of the human genome, and not just any human genome -- that of his slave-holding ancestors. What is the legacy of such a family history, and can DNA say something about it?

In 2000, after a decade in New York City, Ball bought a house in Charleston, South Carolina, home to his father's family for generations, and furnished it with heirloom pieces from his relatives. In one old desk he was startled to discover a secret drawer, sealed perhaps since the Civil War, in which someone had hidden a trove of family hair, with each lock of hair labeled and dated. The strange find propelled him to...

Mitochondrial Function and Biogenesis (Topics in Current Genetics)

Mitochondrial Function and Biogenesis (Topics in Current Genetics)
by Carla M. Koehler (Editor), Matthias F. Bauer (Editor)

Mitochondria are complex organelles, possessing a double-membrane and even their own genome, the mtDNA. They play a pivotal role in cellular metabolism, respiration, and production of ATP essential for the normal function of all human organ systems. It is not surprising, therefore, that genetic defects of mitochondrial functions cause a wide spectrum of human diseases. This book provides the first modern and truly comprehensive coverage of the biochemistry, genetics, and pathology of mitochondria in different organisms. It particularly focuses on the recent advances in our understanding of basic mitochondrial research to the consequences of dysfunction at the molecular level.

The 13 contributions written by leading researchers in the field include topics such as: mitochondrial genome...

  Mitochondrial DNA affinity of several Jewish communities.: An article from: Human Biology
by U. Ritte (Author), E. Neufeld (Author), E.M. Prager (Author), M. Gross (Author), I. Hakim (Author), A. Khatib (Author), B. Bonne-Tamir (Author)

This digital document is an article from Human Biology, published by Wayne State University Press on June 1, 1993. The length of the article is 7324 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

From the author: The mitochondrial DNA (mtDNA) of 332 individuals from Israel, including 270 Jews (originating from 7 communities) and 62 Arabs, was analyzed. Each mtDNA haplotype was determined by the fragment patterns of restriction enzymes HpaI, BamHI, HaeII, MspI (HpaII), and AvaII. The variability of the total sample and of each community was high. Of 40 different haplotypes, 20 were found more than once....

Mitochondrial DNA: Methods and Protocols (Methods in Molecular Biology)

Mitochondrial DNA: Methods and Protocols (Methods in Molecular Biology)
by William C. Copeland (Editor)

National Institutes of Health, Research Triangle Park, NC. Features proven methods for analyzing mitochondrial DNA and the proteins that maintain it; treatment of the genetics, biochemistry, and cell biology of mtDNA; latest developments in applying PCR technology to the analysis of mtDNA; and identification of mtDNA mutations.

  Investigation of congeneric hybridization in and stock structure of weakfish (Cynoscion regalis) inferred from analyses of nuclear and mitochondrial DNA loci *.: An article from: Fishery Bulletin
by Jan F. Cordes (Author), John E. Graves (Author)

This digital document is an article from Fishery Bulletin, published by National Marine Fisheries Service on April 1, 2003. The length of the article is 6255 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Investigation of congeneric hybridization in and stock structure of weakfish (Cynoscion regalis) inferred from analyses of nuclear and mitochondrial DNA loci *.
Author: Jan F. Cordes
Publication: Fishery Bulletin (Refereed)
Date: April 1, 2003
Publisher: National Marine Fisheries Service
Volume: 101 Issue: 2 Page: 443(8)

Distributed by Thomson...

  Mitochondrial DNA and prehistoric settlements: native migrations on the western edge of North America.: An article from: Human Biology
by Jason A. Eshleman (Author), Ripan S. Malhi (Author), John R. Johnson (Author), Frederika A. Kaestle (Author), Joseph Lorenz (Author), David Glenn Smith (Author)

This digital document is an article from Human Biology, published by Wayne State University Press on February 1, 2004. The length of the article is 8275 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

From the author: KEY WORDS: COASTAL MIGRATION, MITOCHONDRIAL DNA, HYPERVARIABLE SEGMENT 1 (HVS1), HOKAN, PENUTIAN, UTO-AZTECAN, LINGUISTIC DIVERSITY, CENTRAL VALLEY OF CALIFORNIA, GREAT BASIN, COLUMBIA PLATEAU, NATIVE AMERICAN GENETICS

Citation Details
Title: Mitochondrial DNA and prehistoric settlements: native migrations on the western edge of North America.
Author: Jason A....

© 2009 BrightSurf.com