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Childhood cancer survivors may have low birth weight children
October 18, 2006Female childhood cancer survivors may face pregnancy problems, including early deliveries and low birth weight children, according to a study in the October 19 Journal of the National Cancer Institute.
New therapies for childhood cancer patients have increased survival, but many scientists are concerned about the long-term effects of the treatments, particularly for patients exposed to radiation and chemotherapy.
Lisa B. Signorello, Sc.D., of the International Epidemiology Institute in Rockville, Md., and colleagues assessed the records of 1,264 female participants in the Childhood Cancer Survivor Study and their 2,201 children. They compared them with 601 cancer-free siblings of survivors and their 1,175 children. The authors assessed possible long-term effects from treatment, such as preterm births, low birth weight, and having babies who were small for their gestational age.
The authors found that survivors' children were more likely than those of siblings to be born early or underweight. The risk was highest when a survivor had their uterus exposed to pelvic radiation as a child.
"Radiotherapy to the pelvis may raise the risks of both preterm birth and restricted fetal growth," they write.
In an accompanying editorial, Leslie Schover, Ph.D., of the University of Texas M.D. Anderson Cancer Center in Houston, discusses the study and the overall interest in preserving fertility for childhood cancer survivors. "Given the complex terrain our young survivors need to traverse, we should design patient and professional education materials that map out the paths to making informed decisions."
Journal of the National Cancer Institute
The authors found that survivors' children were more likely than those of siblings to be born early or underweight. The risk was highest when a survivor had their uterus exposed to pelvic radiation as a child.
"Radiotherapy to the pelvis may raise the risks of both preterm birth and restricted fetal growth," they write.
In an accompanying editorial, Leslie Schover, Ph.D., of the University of Texas M.D. Anderson Cancer Center in Houston, discusses the study and the overall interest in preserving fertility for childhood cancer survivors. "Given the complex terrain our young survivors need to traverse, we should design patient and professional education materials that map out the paths to making informed decisions."
Journal of the National Cancer Institute
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A new study published in the November issue of the Journal of the American College of Surgeons shows that breast cancer patients under 40 years old who undergo fertility preservation do not face a significant delay in the treatment of their disease when their care is coordinated in a timely fashion.
Weight Training Boosts Breast Cancer Survivors' Body Image and Satisfaction with Intimate Relationships, Penn Study Shows
In addition to building muscle, weightlifting is also a prescription for self-esteem among breast cancer survivors, according to new University of Pennsylvania School of Medicine research.
Childhood cancer survivors less likely to marry, Yale researchers find
Adult survivors of childhood cancer are 20 to 25 percent more likely to never marry compared with siblings and the general population, Yale School of Medicine researchers report in a new study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
Brain tumors in childhood leave a lasting mark on cognition, life status
Brain tumors in childhood cast a long shadow on survivors. The first study of the lasting impact of these tumors -- the most common solid malignancies in childhood -- shows that survivors have ongoing cognitive problems.
UB Study Explores How Women Make Decisions About Breast Cancer Surgery
For women just diagnosed with breast cancer, one of the important decisions confronting them is whether to have a lumpectomy or mastectomy. A diagnosis of breast cancer will affect one in every eight women in the United States.
Childhood cancer survivors experience suicidal thoughts decades after diagnosis
Adult survivors of childhood cancer have an increased risk for suicidal thoughts, even decades after their cancer treatments ended, according to a study led by Dana-Farber Cancer Institute scientists.
Sexual problems rarely addressed by internists caring for cancer survivors
Few internists who care for cancer survivors address issues of sexual dysfunction with their patients, according to a study led by Massachusetts General Hospital (MGH) researchers.
Cancer survivors may not be getting the help they need to stop smoking
More than a quarter of cancer survivors who still smoke have not been advised to quit smoking by their health care providers in the last year, according to a study published by researchers at Fox Chase Cancer Center in the current issue of the Journal of General Internal Medicine.
Well-educated women hardest hit by breast cancer
Well-educated women and those who live alone are emotionally the hardest hit by breast cancer, according to the findings of a new Australian study announced during October's Breast Cancer Awareness Month.
OU Part of International Study on Genetic Impact of Radiation
Researchers at the University of Oklahoma Health Sciences Center are helping to lead a massive international study on the possible genetic effects of radiation and cancer drug exposures on future generations.
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