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New radiation technique can greatly reduce painful skin burns in women with breast cancer
November 07, 2006Breast cancer patients who undergo a new radiation technique called intensity modulated radiation therapy (IMRT) after surgery are three times less likely to have severe skin reactions from the treatment compared to standard radiation therapy, according to a study presented at the plenary session November 6, 2006, at the American Society for Therapeutic Radiology and Oncology's 48th Annual Meeting in Philadelphia. The study is the first of its kind to show how recent dramatic improvements in radiation treatments directly benefit patients.
"Using IMRT, we are able to dramatically reduce the painful side effects of radiation, thereby improving the patient's quality of life," said Jean-Philippe Pignol, M.D., Ph.D., lead author of the study and a radiation oncologist at Sunnybrook Health Sciences Centre in Toronto, Canada. "Patients should be aware that breast IMRT has fewer side effects than standard radiation therapy and is now widely available."
The current standard of care for breast cancer is surgical removal of the cancer, followed by radiation to the breast to kill any remaining cells. The standard radiation technique uses two opposite radiation beams on the whole breast to target the cancer and can cause excess amounts of radiation to certain areas of the breast, increasing the risk of the patient developing sensitive, red, weepy skin that may blister and peel. The majority (80 percent) of severe skin burns occur on the breast crease, located between the bottom of the breast and the chest wall.
Using IMRT, however, radiation oncologists are able to control the intensity of each beam to better spare nearby healthy tissue, thereby minimizing the risk of too much radiation on a part of the breast and severe skin reactions. The treatment was able to significantly reduce this occurrence in women with large breasts, who are more likely to have severe skin reactions.
In this study, 358 patients were randomly assigned to receive either the standard breast radiation treatment or breast IMRT and were observed during and for six weeks after treatment.
American Society for Therapeutic Radiology and Oncology
Using IMRT, however, radiation oncologists are able to control the intensity of each beam to better spare nearby healthy tissue, thereby minimizing the risk of too much radiation on a part of the breast and severe skin reactions. The treatment was able to significantly reduce this occurrence in women with large breasts, who are more likely to have severe skin reactions.
In this study, 358 patients were randomly assigned to receive either the standard breast radiation treatment or breast IMRT and were observed during and for six weeks after treatment.
American Society for Therapeutic Radiology and Oncology
Visualizing atomic-scale acoustic wavesin nanostructures
Acoustic waves play many everyday roles - from communication between people to ultrasound imaging. Now the highest frequency acoustic waves in materials, with nearly atomic-scale wavelengths, promise to be useful probes of nanostructures such as LED lights.
PET scans track small tumors after stereotactic body radiotherapy
Readily available CT screening for lung cancer is increasing the discovery of small, primary lung cancers. For many, a radiation technique called stereotactic body radiotherapy presents a less invasive treatment option to surgery that is typically offered to non-surgical candidates.
Lymphedema risk greatly increased with boost of radiation to axillary nodes
The significant risk of developing lymphedema may outweigh the benefit of receiving an extra boost of radiation to lymph nodes possibly involved in early-stage breast cancer.
New radiation technique helps brain cancer patients keep their hair
Patients whose cancer has spread to the brain can avoid typical hair loss (alopecia) when treated with newer radiation techniques, thereby improving their quality of life while still controlling their cancer.
New technique in permanent bradytherapy for the treatment of lung cancer
The University Hospital at Navarre University has developed a system for the percutaneous implantation of palladium 103 seeds, a new technique in permanent bradytherapy for the treatment of lung cancer. Recently, the fourth experiment was carried out and the results remitted to the scientific magazine, "Bradytherapy", for its publication. To date there has been no description in world scientific literature of any case using this therapeutic procedure. The Cl'nica Universitaria has hosted the only cases of bradytherapy using palladium implantation although, in the literature, there exist two articles on the treatment of 8 patients with iodine 125, a radioisotope especially suited to treatmen
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