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Intravenous chemoradiation effective for inoperable head, neck cancer; easier for patients, doctors
November 07, 2006Chemoradiation (radiation and chemotherapy given at the same time) given through a needle or tube inserted into a vein (intravenous) is as effective as treatment given directly to the tumor through a tube inserted into an artery (intra-arterial) for patients with inoperable head and neck cancer, according to a randomized study presented at the plenary session November 6, 2006, at the American Society for Therapeutic Radiology and Oncology's 48th Annual Meeting in Philadelphia.
"We were surprised about the findings because previous studies that were not randomized found that intra-arterial chemoradiation was more effective than intravenous treatment," said Coen Rasch, M.D., Ph.D., lead author of the study and a radiation oncologist at the Netherlands Cancer Institute/Antoni van Leeuwenhoek Huis in Amsterdam, The Netherlands. "Since intravenous chemoradiation is an easier treatment procedure for patients and doctors, it should be considered the standard of care for inoperable head and neck cancer."
The study compared intra-arterial to intravenous chemoradiation in 240 patients with inoperable head and neck cancer, who were assigned to one of the treatment procedures by chance. The chemoradiation was a combination of radiation and cisplatin, a type of chemotherapy that can kill cancer cells, especially when combined with radiation. Results found that both treatment methods were able to control the same amount of cancer growth.
American Society for Therapeutic Radiology and Oncology
American Society for Therapeutic Radiology and Oncology
Chemoradiation Current Events and Chemoradiation News RSSBiodegradable gel being studied as a treatment for esophageal cancer
Gastroenterologists at Rush University Medical Center are studying the safety and efficacy of a new system for delivering chemotherapy for patients with esophageal cancer, a rare, but deadly disease that attacks the throat.
MRI and PET/CT Improve Chances for Optimal Treatment and Minimal Complications in Cervical Cancer Patients
Pretreatment MRI and PET/CT for cervical cancer may direct more women to optimal therapy choices and spare many women potential long-term morbidity and complications of trimodality therapy (surgery followed by chemoradiation), according to a study performed at the Institute for Technology Assessment in Boston, MA.
Glitches in DNA repair genes predict prognosis in pancreatic cancer
Variations in mismatch repair genes can help predict treatment response and prognosis in patients with pancreatic cancer, according to research from The University of Texas M. D. Anderson Cancer Center presented today in advance of the American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium.
How to treat gastroesophageal adenocarcinom patients?
Gastroesophageal adenocarcinomas have a poor prognosis. However, numerous randomized clinical trials (RCT) have evaluated, and continue to evaluate, the survival benefit of various treatment regimens.
CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients
New data show that CAPHOSOL® (www.caphosol.com), an advanced electrolyte solution, relieves painful oral mucositis (OM) and improves quality of life for cancer patients undergoing chemotherapy and radiation therapy.
Study finds cisplatin less effective than standard treatment for patients with anal cancer
When administered before chemoradiation, the common anti-cancer drug cisplatin neither improved disease-free survival nor reduced the number of colostomies needed when compared to the standard treatment for patients with anal canal cancer, according to a study published in the April 23 issue of the Journal of the American Medical Association.
Larynx preservation preferred over total laryngectomy
Patients with locally advanced laryngopharyngeal cancers who receive radical chemoradiation have significantly better voice outcomes during the 12 months following treatment when compared with patients who have undergone a total laryngectomy and surgical voice restoration.
Robotic device appears useful for surgical removal of cancer involving the tonsils
A new robotic surgery technique appears promising for the removal of cancer involving the tonsil region, according to a report in the December issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.
Chemotherapy with gemcitabine delays progression of operable pancreatic cancer
Giving pancreatic cancer patients the chemotherapy drug gemcitabine after surgery delays progression of the disease by about six months, according to new research by Japanese scientists.
Imaging technology helps identify esophageal cancer patients who respond well to treatment
New research at Wake Forest University Baptist Medical Center shows that Positron Emission Tomography (PET) is more accurate than conventional imaging in identifying patients who have good responses to chemotherapy and radiation treatment - a finding that could one day help some patients avoid surgery.
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Chemoradiation: An Integrated Approach to Cancer Treatment by Madhu J., M.D. John (Author), Marshall S., M.D. Flam (Contributor) A comprehensive treatise featuring theoretical background, site specific clinical data with treatment results and toxicity, and ongoing research in the rapidly burgeoning science of chemoradiation. This book succinctly presents the diverse conceptual models, the voluminous pharmacological and biological laboratory data that shapes the science of chemoradiation and explores its potential in the future. | |
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CONCOMITANT CHEMORADIATION: (Current Status and Future) by F. Mornex (Editor), J.J. Mazeron (Editor), J.P. Droz (Editor), M. Marty (Editor) | |
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Chemoradiation in Cancer Therapy (Cancer Drug Discovery and Development) by Hak Choy (Editor) Vanderbilt Univ., Nashville, TN. Offers an understanding of current and future strategies available for the treatment of solid tumors by chemotherapeutic agents. Includes the integration of new molecular-targeted agents and discussions at the molecular level. Electronic format not yet available. DNLM: Neoplasms--drug therapy. |
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Chemoradiation: Webster's Timeline History, 1986 - 2007 by Icon Group International (Author) Webster's bibliographic and event-based timelines are comprehensive in scope, covering virtually all topics, geographic locations and people. They do so from a linguistic point of view, and in the case of this book, the focus is on "Chemoradiation," including when used in literature (e.g. all authors that might have Chemoradiation in their name). As such, this book represents the largest compilation of timeline events associated with Chemoradiation when it is used in proper noun form. Webster's timelines cover bibliographic citations, patented inventions, as well as non-conventional and alternative meanings which capture ambiguities in usage. These furthermore cover all parts of speech (possessive, institutional usage, geographic usage) and contexts, including pop culture, the arts,... |
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