 |
|
Lymphedema risk greatly increased with boost of radiation to axillary nodes
November 09, 2006The significant risk of developing lymphedema may outweigh the benefit of receiving an extra boost of radiation to lymph nodes possibly involved in early-stage breast cancer. That is the conclusion of a study presented today at the 48th Annual Meeting of the American Society for Therapeutic Radiology and Oncology in Philadelphia.
Lymphedema is an uncomfortable swelling of a limb caused by a build-up of lymphatic fluid. This occurs when the lymph vessels are damaged and/or nodes are removed. The disruption of lymphatic flow prevents the proper drainage, causing a back-up of fluid. About 15-20% of women with breast cancer who have lymph nodes removed during surgery will develop lymphedema.
"We know radiation can increase one's risk of developing lymphedema, so it's important to determine whether the radiation technique or dose contributes," explained Shelly B. Hayes, M.D., a resident in the radiation oncology department at Fox Chase Cancer Center and lead author of the new study.
Standard therapy for women with early-stage breast cancer calls for radiation following a lumpectomy. The radiation field includes the whole affected breast and some of the lymph nodes under the arm, called the axillary lymph nodes.
Doctors may also irradiate the lymph nodes found in the upper axilla and above the clavicle (collar bone), depending on the number of nodes removed and the number that test positive for cancerous cells). Sometimes, an additional dose or "boost" of radiation is added to the axillary region.
"The reason we irradiate the lymph node regions is to prevent recurrence of disease in those locations," Hayes said. "When an aggressive lymph-node dissection is performed, the utility of additional radiation is questionable. This is the subject of some debate."
Hayes' study consisted of 2,581 women with early-stage breast cancer treated at Fox Chase Cancer Center with lumpectomy, axillary-node dissection and radiation between 1970 and 2005. A total of 2,174 patients (84%) were treated with radiation to the breast alone, 221patients (8.6%) were treated to the breast and supraclavicular lymph nodes (those above the collar bone) while 184 patients (7.1%) received an additional boost of radiation to the axillary nodes. The median follow-up was 81 months.
"The most striking result we found involved women who had more than four positive lymph nodes," explained Hayes. "They were four times more likely to develop lymphedema when treated with a boost, despite similar risks of nodal recurrences.
"Given the increased risk of lymphedema and the lack of evidence supporting improvements in nodal recurrences from the boost, we should carefully consider these results before delivering a boost to our patients,\\\
Fox Chase Cancer Center
Standard therapy for women with early-stage breast cancer calls for radiation following a lumpectomy. The radiation field includes the whole affected breast and some of the lymph nodes under the arm, called the axillary lymph nodes.
Doctors may also irradiate the lymph nodes found in the upper axilla and above the clavicle (collar bone), depending on the number of nodes removed and the number that test positive for cancerous cells). Sometimes, an additional dose or "boost" of radiation is added to the axillary region.
"The reason we irradiate the lymph node regions is to prevent recurrence of disease in those locations," Hayes said. "When an aggressive lymph-node dissection is performed, the utility of additional radiation is questionable. This is the subject of some debate."
Hayes' study consisted of 2,581 women with early-stage breast cancer treated at Fox Chase Cancer Center with lumpectomy, axillary-node dissection and radiation between 1970 and 2005. A total of 2,174 patients (84%) were treated with radiation to the breast alone, 221patients (8.6%) were treated to the breast and supraclavicular lymph nodes (those above the collar bone) while 184 patients (7.1%) received an additional boost of radiation to the axillary nodes. The median follow-up was 81 months.
"The most striking result we found involved women who had more than four positive lymph nodes," explained Hayes. "They were four times more likely to develop lymphedema when treated with a boost, despite similar risks of nodal recurrences.
"Given the increased risk of lymphedema and the lack of evidence supporting improvements in nodal recurrences from the boost, we should carefully consider these results before delivering a boost to our patients,\\\
Fox Chase Cancer Center
Lymphedema Current Events and Lymphedema News RSSWeight Training Boosts Breast Cancer Survivors' Body Image and Satisfaction with Intimate Relationships, Penn Study Shows
In addition to building muscle, weightlifting is also a prescription for self-esteem among breast cancer survivors, according to new University of Pennsylvania School of Medicine research.
New Discovery Brings Hope to Treatment of Lymphatic Diseases
Researchers in the laboratory of Dr. Jayakrishna Ambati at the University of Kentucky have discovered the first naturally occurring molecule that selectively blocks lymphatic vessel growth.
Study links arm/hand swelling to number of lymph nodes removed during breast cancer surgery
In older breast cancer survivors, the number of lymph nodes removed during surgery and the presence of cancer in the lymph nodes were the two factors most directly linked to the development of lymphedema, swelling of the arm and hand.
Obesity Increases Lymphedema Risk for Breast Cancer Survivors
Throughout the world, 10 million breast cancer survivors have a lifetime risk for developing lymphedema, a chronic condition that involves swelling of the limbs and impacts physical and psychosocial health.
MU Study Identifies Patient Strategies for Managing Symptoms of Lymphedema
An estimated 2 million women in the United States are at risk of developing lymphedema, a condition that involves the chronic and abnormal swelling of the arm, chest, neck and/or back, as a complication of breast cancer treatment.
Study suggests some breast cancer patients facing radiation after a mastectomy may be over-treated
A new study suggests standard radiation therapy for some breast cancer patients may not be medically required and may, therefore, be causing unnecessary serious side effects such as lymphedema and pulmonary problems.
M. D. Anderson nurse addresses lymphedema in breast cancer patients and survivors
A poster session presented today by The University of Texas M. D. Anderson Cancer Center at the Oncology Nurses Society 33rd Annual Congress, found that early nursing intervention and implementation of effective strategies can lead to a decrease in the incidence of lymphedema, better management of chronic lymphedema and improved quality of life in breast cancer patients.
Preoperative assessment of cancer patients enables early diagnosis, treatment of lymphedema
The preoperative assessment of breast cancer patients for subclinical lymphedema enables clinicians to establish a baseline, which serves to enable the early diagnosis and successful treatment of the debilitating condition.
Venous origin of the mammalian lymphatic vasculature
In the October 1 issue of G&D, Dr. Guillermo Oliver (St. Jude Children's Research Hospital) and colleagues present new evidence to resolve a century-old debate over the origin of the mammalian lymphatic vasculature.
Exercise and yoga improves quality of life in women with early-stage breast cancer
Two studies report that exercise and yoga can help maintain and in some cases improve quality of life in women with early-stage breast cancer.
More Lymphedema Current Events and Lymphedema News Articles
 |
Living Well with Lymphedema by Ann B. Ehrlich (Author), Alma Vinje-Harrewijn (Author), Elizabeth J. McMahon (Author) Living Well with Lymphedema is a comprehensive resource for those with, or at risk of developing, lymphedema. This easy-to-read, generously illustrated, 280 page book contains the information necessary to understand what lymphedema is, what causes it, how it is treated, self-management steps to control your condition, practical suggestions for mastering the emotional challenges of living with a chronic condition, plus an illustrated guide to understanding the lymphatic system. LymphNotes.com, a highly respected lymphedema oriented web site, provides insights into the needs and interests of individuals with, at risk for, or caring for people with lymphedema. |
 |
Lymphedema: A Breast Cancer Patient's Guide to Prevention and Healing by Jeannie Burt (Author), Gwen White (Author) Women who undergo surgery for breast cancer may end up with lymphedema, a painful, visible swelling, usually of the arm. Coming to their aid, Lymphedema lays out the many options for preventing and treating the condition. The book provides information on reducing lymphedema through professional therapy as well as exercise and self-massage, plus helpful illustrations and additional resources. It also tells encouraging stories of women who have dealt with lymphedema successfully. With updates throughout on the latest research, products, and techniques, this new edition features expanded nutrition and exercise sections and covers naturopathy, acupuncture, and Chinese herbal medicine, as well as potential future therapies being tested. |
 |
ACS Complete Guide to Lymphedema: Understanding and Managing Lymphedema After Cancer Treatment by American Cancer Society (Author) Providing Answers About Lymphedema “Except for recurrence of breast cancer, no event is more dreaded than the development of lymphedema,” said Marilyn Kwan, PhD, a lymphedema researcher quoting from an article in the journal Cancer. This little known and mystifying condition is comprehensively discussed in the American Cancer Society’s Complete Guide to Lymphedema. This essential guide is designed to be a practical handbook of how to cope with and manage complex physical and emotional lymphedemarelated issues. |
 |
Lymphedema Management: The Comprehensive Guide for Practitioners (Complementary Medicine (Thieme Hardcover)) by Joachim Zuther (Author) An up-to-date guide to the diagnosis and treatment of lymphedema<br><br>"A well-written textbook that is clear and concise. The organization is exceptional; each chapter is color-coded for ease in locating or browsing through information, and colored shadings in the text emphasize important points. Students and patients interested in this topic will find exceptional value in reading this book. The quality and readability are excellent." --Physical Therapy<br><br>This comprehensive textbook discusses current approaches to managing primary and secondary lymphedema and related conditions, such as chronic venous insufficiency, edema, and rheumatoid arthritis. It provides thorough coverage of the anatomy, physiology, and pathology of the lymphatic system, and explains... |
 |
Lymphatic Drainage Starring: Sean Riehl This beautiful video will guide you through the anatomy of the lymphatic system, the location of nodes and drainage patterns, as well as contraindications and indications for lymphatic drainage massage. Then Sean Riehl skillfully guides you step by step through over 60 techniques covering the face and body. With a clear presentation and hundreds of computer graphics, learning lymphatic drainage has never been easier. Also included are techniques to perform lymphatic drainage on yourself, as well as an interview with Allen Mills, a prominent lymphatic drainage therapist. Don't Miss out! Improve your skills by learning lymphatic drainage today! |
 |
Huntleigh Flowtron Hydroven 3 Lymphedema Pump by HUNTLEIGH HEALTHCARE This is a simple and lightweight pump. Has preset cycles and adjustable pressure settings for comfort. Safe and effective for both clinic andÂhome use. |
 |
Coping with Lymphedema by Diane Sackett Nannery (Author), Joan Swirsky (Author) A side effect of cancer surgery, radiation treatments, or traumatic accident, lymphedema causes the extreme swelling of a limb or other part of the body. This book provides comprehensive, current information on this condition and its treatment, including diet and exercise, lifestyle modifications, and finding qualified therapists. |
 |
Lymphedema: Understanding and Managing Lymphedema After Cancer Treatment by American Cancer Society (Author) Understand the mystery of cancer-related lymphedema If you have had cancer treatment, you may be at risk for lymphedema, a buildup of fluid that results in swelling of the arm or leg and other potential complications. Created with the guidance of experts in nursing, oncology, research, and lymphedema care, this up-to-date, practical handbook helps you and your caregiver understand and manage every aspect of lymphedema. Topics include: Current recommendations about day-to-day precautions, diagnosis, and treatment Early symptoms and self-monitoring that can be essential to early diagnosis Methods of coping with emotional stresses and physical challenges Practical issues related to work, insurance, and finding and paying for treatmentLymphedema:... |
 |
Voices of Lymphedema: stories, advice, and inspiration from patients and therapists by Ann B. Ehrlich (Editor), Elizabeth J. McMahon (Editor), Calina Burns (Editor) Chronic swelling due to lymphatic fluid, or lymphedema, affects 3-5 million Americans including 20-40% of cancer survivors. Lymphedema is so little known-even among doctors-that it has been called the 'silent epidemic' but there is effective treatment that can break the cycle of recurring infections and even reverse lymphedema related disability! Patients, therapists, and doctors share: . Inspiring personal stories. . Advice on getting a diagnosis and finding treatment. . Solutions to common problems and practical tips on self-care. . Activities they enjoy and travel tips. . Support groups and outreach to the medical community. . Issues in treatment coverage and reimbursement. About the Editors: Ann Ehrlich and Elizabeth McMahon are coauthors of Living Well With Lymphedema... |
 |
Lymphedema Caregiver's Guide: arranging and providing home care by Mary Kathleen Kearse (Author), Elizabeth Jane McMahon (Author), Ann B. Ehrlich (Author), Paula J. B. Stewart (Foreword) Lymphedema Caregiver's Guide is the first book to provide detailed instructions for caregivers on all aspects of lymphedema (lymphoedema) home care including physical care (skin care, simple lymph drainage, compression, exercise, etc.), communications skills and emotional support, and activities of daily living. Caregivers will also learn ways to protect themselves from injury and burnout. Caregiver's Guide outlines a systematic approach to determining the patient's care needs, arranging care, and coordinating multiple caregivers. Trained lymphedema caregivers are in short supply now and we face a `care gap' in the near future as the number of people needing care increases while the pool of potential family caregivers shrinks. This book is an important first step in the process... |
| © 2009 BrightSurf.com |