Science Current Events | Science News | Brightsurf.com
 

Largest PSA bounce study eases worry of prostate cancer returning

November 09, 2006

Prostate cancer patients who have a temporary rise in their prostate specific antigen (PSA) levels after radiation therapy-called a PSA bounce-are not at an increased risk of their cancer coming back any more than those who don't have a temporary rise, according to the largest study of its kind presented November 8, 2006, at the American Society for Therapeutic Radiology and Oncology's 48th Annual Meeting in Philadelphia.

External beam radiation therapy and radiation seed implants are two of the main treatments for prostate cancer. Since these treatments are minimally invasive, have short recovery periods and often help men preserve their sexual and urinary function, many men with prostate cancer prefer radiation over other treatments, including surgery. The PSA bounce is common in half of all men who have radiation treatment for prostate cancer. Increased levels of PSA, which is a protein produced by the prostate, may be a sign of prostate cancer.

"I believe the results of our study should help reduce the stress and uncertainty for men who experience a PSA bounce after radiation knowing that this doesn't represent a recurrence or put them at increased risk for cancer coming back later on," said Eric Horwitz, M.D., lead author of the study and clinical director of the radiation oncology department at Fox Chase Cancer Center in Philadelphia. "This study significantly impacts the clinical practice for both radiation oncologists and urologists. Clinicians should consider additional PSA tests after the initial bounce to see if the PSA levels return to normal before concluding that cancer has recurred and recommending additional treatment."

The study involved more than 7,500 men in 19 institutions who were treated for prostate cancer with either external beam radiation therapy or radiation seed implants. Findings show that over a 10-year period, there was no difference in cancer recurrence between those who had a PSA bounce and those who did not.

American Society for Therapeutic Radiology and Oncology


Related Prostate Cancer Current Events and Prostate Cancer News Articles


Women may be able to reduce breast cancer risk predicted by their genes
Women with a high risk of developing breast cancer based on family history and genetic risk can still reduce the chance they will develop the disease in their lifetimes by following a healthy lifestyle, new research led by the Johns Hopkins Bloomberg School of Public Health suggests.

Coping with active surveillance anxiety in prostate cancer
Men with prostate cancer who are under close medical surveillance reported significantly greater resilience and less anxiety over time after receiving an intervention of mindfulness meditation, according to a recently published pilot study from the Northwestern University Feinberg School of Medicine.

Differences in metabolism between androgen-dependent and castration resistant prostate cancer may lead to new therapies
Advanced prostate cancer is usually treated by removing androgen, the male hormone that helps it grow.

Exercise, future anticancer therapy?
At age 70, Alfred Roberts plays hockey twice a week. Nothing special, right? Except that for three years he has had advanced prostate cancer, which has spread to his bones.

Two-stage nanoparticle delivery of piperlongumine and TRAIL anti-cancer therapy
A team of researchers from Cornell University in Ithaca, New York demonstrated a drug delivery mechanism that utilizes two independent vehicles, allowing for delivery of chemically and physically dis-tinct agents.

In obese prostate cancer patients, robotic surgery reduces risk of blood loss
In obese prostate cancer patients, robotic-assisted surgery to remove the prostate reduces the risk of blood loss and prolonged hospital stays, a Loyola Medicine study has found.

New PSA test examines protein structures to detect prostate cancers
A promising new test is detecting prostate cancer more precisely than current tests, by identifying molecular changes in the prostate specific antigen (PSA) protein, according to Cleveland Clinic research presented today at the American Urological Association annual meeting.

Radiotherapy halves deaths from prostate cancer 15 years after diagnosis
A longitudinal Nordic study, comparing the results of hormone (antiandrogen) therapy with or without the addition of local radiotherapy, shows that a combination of treatments halves the risk of death from prostate cancer 15 years after diagnosis.

Preliminary results comparing PD-L1 IHC diagnostic assays in lung cancer released
A pre-competitive consortia of pharmaceutical companies, diagnostic companies, and academic associations, including the International Association for the Study of Lung Cancer (IASLC), announced phase I results of the "BLUEPRINT PD-L1 IHC ASSAY COMPARISON PROJECT" at the Annual Meeting of the American Association for Cancer Research (AACR) on April 19.

Cancer may drive health problems as people age
A new study indicates that cancer may have negative impacts on both the physical and mental health of individuals as they age.
More Prostate Cancer Current Events and Prostate Cancer News Articles

Dr. Patrick Walsh's Guide to Surviving Prostate Cancer

Dr. Patrick Walsh's Guide to Surviving Prostate Cancer
by Patrick C. Walsh (Author), Janet Farrar Worthington (Author)


Each year, more than 230,000 men are diagnosed with prostate cancer, and 30 to 40 percent of patients who are diagnosed will eventually relapse. But the good news is that more men are being cured of this disease than ever before. Now in a revised third edition, this lifesaving guide by Dr. Patrick Walsh and award-winning science writer Janet Farrar Worthington offers a message of hope to every man facing this illness. Prostate cancer is a different disease in every man, which means that the right treatment varies for each man. Readers will discover their risk factors, simple changes that can reduce the risk of developing the disease, treatment options, and more.

This new edition is updated to maintain its cutting edge as the world's most popular and well-respected resource on...

You Can Beat Prostate Cancer: And You Don't Need Surgery to Do It

You Can Beat Prostate Cancer: And You Don't Need Surgery to Do It
by Robert J. Marckini (Author)


The task of choosing the right prostate cancer treatment is daunting. It is further complicated by conflicting information the patient receives from physicians and the Internet. This book is written by a prostate cancer survivor who now runs an international prostate cancer support group. It's about his journey and the important things he learned along the way. It is the book the author wishes had been available when he was diagnosed 6 years ago. It is intended to provide specific information for men who are at risk or have been recently diagnosed with prostate cancer. All major treatment options are examined and the pros and cons of each are summarized. A relatively new, non-invasive, highly effective treatment is highlighted. It is an option that cures cancer as well as any other...

"Prostate Cancer Breakthroughs 2014: New Tests, New Treatments, Better Options: A Step-by-Step Guide to Cutting-Edge Diagnostic Tests and 12 Medically-Proven Treatments

"Prostate Cancer Breakthroughs 2014: New Tests, New Treatments, Better Options: A Step-by-Step Guide to Cutting-Edge Diagnostic Tests and 12 Medically-Proven Treatments
by Jay S. Cohen (Author)


"Vital new information for men diagnosed with prostate cancer!" --George Johnson, Director of the Informed Prostate Cancer Support Group in San Diego, the largest independent group in California

"I have had treatment for prostate cancer and have been thru the mill. If I were going to go through the process again, I would start with Dr Cohen's book." --P.C., independent review at Amazon.com

Updated for 2014, Prostate Cancer Breakthroughs 2014 offers 55 additional pages from the original top-selling book. Also, new information on PSA testing, how to obtain a new targeted biopsy, and the 16 additional centers now offering the key test: prostate-specific, Tesla 3 MRI. Fast reading, easy to understand, step-by-step, Prostate Cancer Breakthroughs 2014 takes you through the...

Prostate Cancer, Second Edition: Science and Clinical Practice

Prostate Cancer, Second Edition: Science and Clinical Practice
by Jack H. Mydlo MD FACS (Editor), Ciril J. Godec (Editor)


Prostate Cancer, Science and Clinical Practice, Second Edition, continues to be an important translational reference that bridges the gap between science and clinical medicine. It reviews the biological processes that can be implicated in the disease, reviews current treatments, highlights the pitfalls where relevant, and examines the scientific developments that might result in future treatments. Key chapters from the previous edition have been updated, and a plethora of new chapters describe new concepts of prostate cancer biology and newly developed therapeutics. Each chapter has been written by internationally recognized specialists on prostate cancer epidemiology, genetic susceptibility, cancer metastases, prostate physiology, proteomics, new therapeutics, and clinical...

Thrive Don't Only Survive: Dr.Geo's Guide to Living Your Best Life Before & After Prostate Cancer

Thrive Don't Only Survive: Dr.Geo's Guide to Living Your Best Life Before & After Prostate Cancer
by Dr. Geo Espinosa (Author)


Prostate cancer is not the end—it’s the beginning. It’s the point where you start taking control. Information on what to do isn't hard to find. There are dozens of books on prostate cancer, as well as a massive amount of online resources. What's lacking, however, is a trusted, reliable source on implementing the abundance of scientific evidence in a way that’s realistic and sustainable. Based on his extensive research and clinical experience on natural medicine for prostate problems, Dr. Geo has created a lifestyle blueprint that men can apply immediately to thrive before or after prostate cancer. Dr. Geo walks readers of every stage and age (as well as their partners) through the steps to become a thriver, not just a survivor. This book delivers invaluable information and...

The Man Within Me: My Victory Over Prostate Cancer

The Man Within Me: My Victory Over Prostate Cancer
by Eric E Ludin (Author), Dr. Li-Ming Su (Foreword)


Every year thousands of men are told that they have prostate cancer. This diagnoses causes fear and anxiety heightened by the numerous options their physicians often lay out for them. Men are forced to select one of a variety of treatment choices or decide to have no treatment at all. Often these men cannot make a decision because of the difficulty in finding answers to their questions about how their life will change. In this book, attorney Eric E. Ludin describes his experiences upon learning of his diagnosis and how he made his decision to have a radical prostatectomy. Using humor and warmth, he describes with detail how removal of his prostate has affected his life both physically and emotionally. He addresses the emotion and fear that men often encounter during this difficult time...

Prostate and Cancer: A Family Guide to Diagnosis, Treatment, and Survival

Prostate and Cancer: A Family Guide to Diagnosis, Treatment, and Survival
by Sheldon Marks (Author)


Prostate cancer is one of the most common cancers affecting American men, with over 186,000 new cases diagnosed in the United States annually; 1 in 6 men will be diagnosed with prostate cancer during his lifetime. Renowned prostate cancer specialist Sheldon Marks offers the definitive guide for men concerned about or diagnosed with prostate cancer, and for their families.Since the third edition (2003), there have been significant changes in treatment and resources. Working with Dr. Judd Moul, the Chairman of Urology at Duke and one of the world's top experts on prostate cancer, Marks provides the most up-to- date information on diagnosis, treatment, and common questions.

100 Questions  &  Answers About Prostate Cancer

100 Questions & Answers About Prostate Cancer
by Pamela Ellsworth (Author)


100 Questions & Answers About Prostate Cancer provides authoritative and practical answers to the most common questions asked by patients and their loved ones. Providing both doctor and patient perspectives, this easy-to-read book is a comprehensive guide to the basics of prostate cancer, risk factors and prevention, diagnosis, treatment, survivorship, and life after diagnosis. Written by Dr. Pamela Ellsworth, a prominent urologist and best-selling author, Questions & Answers About Prostate Cancer is an invaluable resource for anyone interested in learning what to expect after being diagnosed with prostate cancer.

The Great Prostate Hoax: How Big Medicine Hijacked the PSA Test and Caused a Public Health Disaster

The Great Prostate Hoax: How Big Medicine Hijacked the PSA Test and Caused a Public Health Disaster
by Richard J. Ablin (Author), Ronald Piana (Author)


Every year, more than a million men undergo painful needle biopsies for prostate cancer, and upward of 100,000 have radical prostatectomies, resulting in incontinence and impotence. But the shocking fact is that most of these men would never have died from this common form of cancer, which frequently grows so slowly that it never even leaves the prostate. How did we get to a point where so many unnecessary tests and surgeries are being done? In The Great Prostate Hoax, Richard J. Ablin exposes how a discovery he made in 1970, the prostate-specific antigen (PSA), was co-opted by the pharmaceutical industry into a multibillion-dollar business. He shows how his discovery of PSA was never meant to be used for screening prostate cancer, and yet nonetheless the test was patented and...

PROSTATE CANCER Asking the Right Questions

PROSTATE CANCER Asking the Right Questions
by Fertile Ground Press


With prostate cancer the medical community is selling tests and treatment options, and men are buying. It is imperative to recognize that: (1) Prostate cancer is not just a disease - it is big business; (2) There is no single preferred treatment endorsed by the medical community; (3) New imaging technology has brought new diagnostic capabilities and lower risk treatment options for men who qualify; (4) You must be prepared to ask the right questions to increase your chance of having a good outcome. If you follow "The Prostate Cancer Check List" provided in this book, you will be able to ask the right questions, and you just might save, extend or improve the quality of your life.

© 2016 BrightSurf.com