Science Current Events | Science News | Brightsurf.com
 

Largest PSA bounce study eases worry of prostate cancer returning

November 09, 2006
Prostate cancer patients who have a temporary rise in their prostate specific antigen (PSA) levels after radiation therapy-called a PSA bounce-are not at an increased risk of their cancer coming back any more than those who don't have a temporary rise, according to the largest study of its kind presented November 8, 2006, at the American Society for Therapeutic Radiology and Oncology's 48th Annual Meeting in Philadelphia.

External beam radiation therapy and radiation seed implants are two of the main treatments for prostate cancer. Since these treatments are minimally invasive, have short recovery periods and often help men preserve their sexual and urinary function, many men with prostate cancer prefer radiation over other treatments, including surgery. The PSA bounce is common in half of all men who have radiation treatment for prostate cancer. Increased levels of PSA, which is a protein produced by the prostate, may be a sign of prostate cancer.

"I believe the results of our study should help reduce the stress and uncertainty for men who experience a PSA bounce after radiation knowing that this doesn't represent a recurrence or put them at increased risk for cancer coming back later on," said Eric Horwitz, M.D., lead author of the study and clinical director of the radiation oncology department at Fox Chase Cancer Center in Philadelphia. "This study significantly impacts the clinical practice for both radiation oncologists and urologists. Clinicians should consider additional PSA tests after the initial bounce to see if the PSA levels return to normal before concluding that cancer has recurred and recommending additional treatment."

The study involved more than 7,500 men in 19 institutions who were treated for prostate cancer with either external beam radiation therapy or radiation seed implants. Findings show that over a 10-year period, there was no difference in cancer recurrence between those who had a PSA bounce and those who did not.

American Society for Therapeutic Radiology and Oncology


Related Prostate Cancer Current Events and Prostate Cancer News Articles


Blood test could identify when cancer treatment has become detrimental
Some treatments for prostate cancer, while initially effective at controlling the disease, not only stop working over time but actually start driving tumour growth, a major new study shows.

Moffitt Cancer Center Researchers Help Lead International Efforts to Find New Genetic Links to Prostate Cancer
Researchers at Moffitt Cancer Center, including Center Director Thomas A. Sellers, Ph.D., M.P.H., Jong Park, Ph.D. and Hui-Yi Lin, Ph.D., have discovered 23 new regions of the genome that influence the risk for developing prostate cancer, according to a study published Sept. 14 in Nature Genetics.

Large study reveals new genetic variants that raise risk for prostate cancer
In an analysis of genetic information among more than 87,000 men, a global team of scientists says it has found 23 new genetic variants - common differences in the genetic code -- that increase a man's risk for prostate cancer.

New non-invasive technique could revolutionize the imaging of metastatic cancer
Bioluminescence, nanoparticles, gene manipulation - these sound like the ideas of a science fiction writer, but, in fact, they are components of an exciting new approach to imaging local and metastatic tumors.

Study identifies when and how much various prostate cancer treatments will impact urinary and sexual functioning
Men with prostate cancer may one day be able to predict when and how much various treatments will impact their urinary and sexual functioning.

Genetic Discovery Yields Prostate Cancer Test, Promise of Future Therapy
A genetic discovery out of the University of Pittsburgh School of Medicine is leading to a highly accurate test for aggressive prostate cancer and identifies new avenues for treatment.

Certain Form of Baldness at Age 45 Linked to Higher Risk of Aggressive Prostate Cancer
A new, large cohort analysis from the prospective Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial, indicates that men who had moderate baldness affecting both the front and the crown of their head at age 45 were at a 40% increased risk of developing aggressive prostate cancer (usually indicates a faster growing tumor resulting in poorer prognosis relative to non-aggressive prostate cancer) later in life, compared to men with no baldness.

Genetic testing can identify men at 6-fold increased risk of prostate cancer
Scientists can now explain a third of the inherited risk of prostate cancer, after a major international study identified 23 new genetic variants associated with increased risk of the disease.

Penn Study Finds Genetic Mutations Linked With Ethnic Disparities in Cancer
One of the goals of genome sequencing is to identify genetic mutations associated with increased susceptibility to disease.

The newest precision medicine tool: Prostate cancer organoids
Research led by investigators at Memorial Sloan Kettering Cancer Center has shown for the first time that organoids derived from human prostate cancer tumors can be grown in the laboratory, giving researchers an exciting new tool to test cancer drugs and personalize cancer treatment.
More Prostate Cancer Current Events and Prostate Cancer News Articles

"Prostate Cancer Breakthroughs 2014: New Tests, New Treatments, Better Options: A Step-by-Step Guide to Cutting-Edge Diagnostic Tests and 12 Medically-Proven Treatments

"Prostate Cancer Breakthroughs 2014: New Tests, New Treatments, Better Options: A Step-by-Step Guide to Cutting-Edge Diagnostic Tests and 12 Medically-Proven Treatments
by Jay S. Cohen (Author)


"Vital new information for men diagnosed with prostate cancer!" --George Johnson, Director of the Informed Prostate Cancer Support Group in San Diego, the largest independent group in California

"I have had treatment for prostate cancer and have been thru the mill. If I were going to go through the process again, I would start with Dr Cohen's book." --P.C., independent review at Amazon.com

Updated for 2014, Prostate Cancer Breakthroughs 2014 offers 55 additional pages from the original top-selling book. Also, new information on PSA testing, how to obtain a new targeted biopsy, and the 16 additional centers now offering the key test: prostate-specific, Tesla 3 MRI. Fast reading, easy to understand, step-by-step, Prostate Cancer Breakthroughs 2014 takes you through the...

Dr. Patrick Walsh's Guide to Surviving Prostate Cancer

Dr. Patrick Walsh's Guide to Surviving Prostate Cancer
by Patrick C. Walsh (Author), Janet Farrar Worthington (Author)


Each year, more than 230,000 men are diagnosed with prostate cancer, and 30 to 40 percent of patients who are diagnosed will eventually relapse. But the good news is that more men are being cured of this disease than ever before. Now in a revised third edition, this lifesaving guide by Dr. Patrick Walsh and award-winning science writer Janet Farrar Worthington offers a message of hope to every man facing this illness. Prostate cancer is a different disease in every man, which means that the right treatment varies for each man. Readers will discover their risk factors, simple changes that can reduce the risk of developing the disease, treatment options, and more.

This new edition is updated to maintain its cutting edge as the world's most popular and well-respected resource on...

PROSTATE CANCER Asking the Right Questions

PROSTATE CANCER Asking the Right Questions
by Thomas J. Leih


With prostate cancer the medical community is selling tests and treatment options, and men are buying. It is imperative to recognize that: (1) Prostate cancer is not just a disease - it is big business; (2) There is no single preferred treatment endorsed by the medical community; (3) You must be prepared to ask the right questions to increase your chance of having a good outcome. If you follow "The Prostate Cancer Check List" provided in this book, then you will be able to ask the right questions, and you just might save or extend your life.

You Can Beat Prostate Cancer: And You Don't Need Surgery to Do It

You Can Beat Prostate Cancer: And You Don't Need Surgery to Do It
by Robert J. Marckini (Author)


The task of choosing the right prostate cancer treatment is daunting. It is further complicated by conflicting information the patient receives from physicians and the Internet. This book is written by a prostate cancer survivor who now runs an internatio

The Decision: Your prostate biopsy shows cancer. Now what?: Medical insight, personal stories, and humor by a urologist who has been where you are now.

The Decision: Your prostate biopsy shows cancer. Now what?: Medical insight, personal stories, and humor by a urologist who has been where you are now.
by John C. McHugh M.D. (Author), Johanna C. Craig Ph.D. (Editor), Graham L. Gaines (Editor), William P. Black (Editor), Travis Massey (Editor), Sandra B. Brim Ph.D. (Editor), Janice K. Watts (Editor)


Over 200,000 times a year in the U.S. a patient will leave his urologist's office having been told he has prostate cancer. What the patient thought to be a disease of old men from which they do not die, now becomes a very complicated and frustrating dilemma about which treatment to pursue. "The Decision" offers the reader an insider's view to the key issues necessary for a well thought-out treatment plan peculiar only to him. Being a urologist who treats prostate cancer and having had the disease as well, uniquely positions the author in offering guidance to the newly diagnosed prostate cancer patient. Dr. McHugh outlines a novel and multifaceted approach, using an eclectic mix of medical insight ,personal stories and humor, to aid the reader in making his "Decision." The US Review of...

Prostate and Cancer: A Family Guide to Diagnosis, Treatment, and Survival

Prostate and Cancer: A Family Guide to Diagnosis, Treatment, and Survival
by Sheldon Marks MD (Author)


Prostate cancer is one of the most common cancers affecting American men, with over 186,000 new cases diagnosed in the United States annually; 1 in 6 men will be diagnosed with prostate cancer during his lifetime. Renowned prostate cancer specialist Sheldon Marks offers the definitive guide for men concerned about or diagnosed with prostate cancer, and for their families.Since the third edition (2003), there have been significant changes in treatment and resources. Working with Dr. Judd Moul, the Chairman of Urology at Duke and one of the world’s top experts on prostate cancer, Marks provides the most up-to- date information on diagnosis, treatment, and common questions.

The Prostate Health Diet: What to Eat to Prevent and Heal Prostate Problems Including Prostate Cancer, BPH Enlarged Prostate and Prostatitis

The Prostate Health Diet: What to Eat to Prevent and Heal Prostate Problems Including Prostate Cancer, BPH Enlarged Prostate and Prostatitis
by Ronald M Bazar (Author), Coreen Boucher (Editor)


Do you know the best diet for your prostate gland?
Do you know the best diet for preventing or curing prostate cancer?
Do you know the best diet for your prostate health and to prevent prostate disease? Most men don’t. The Prostate Health Diet show you how to find the best diet for you and how to customize your diet for optimum health and your uniqueness. The Prostate Health Diet is not a fad diet. It will guide you to find what will work for you with practical insights into the often conflicting views of what you should do. It will simplify complex issues with insights that will make sense to you. You will know what to eat and why and learn how to know for sure. Your prostate is a gland, which—among its many functions—filters out toxins from your ejaculate. That means...

The Great Prostate Hoax: How Big Medicine Hijacked the PSA Test and Caused a Public Health Disaster

The Great Prostate Hoax: How Big Medicine Hijacked the PSA Test and Caused a Public Health Disaster
by Richard J. Ablin (Author), Ronald Piana (Author)


Every year, more than a million  men undergo painful needle biopsies for prostate cancer, and upward of 100,000 have radical prostatectomies, resulting in incontinence and impotence. But the shocking fact is that most of these men would never have died from this common form of cancer, which frequently grows so slowly that it never even leaves the prostate. How did we get to a point where so many unnecessary  tests and surgeries are being done? In The Great Prostate Hoax, Richard J. Ablin exposes how a discovery he made in 1970, the prostate-specific antigen (PSA), was co-opted by the pharmaceutical industry into a multibillion-dollar   business. He shows how his discovery of PSA was never meant to be used for screening prostate cancer, and yet nonetheless the test was patented and...

Dr. Peter Scardino's Prostate Book, Revised Edition: The Complete Guide to Overcoming Prostate Cancer, Prostatitis, and BPH

Dr. Peter Scardino's Prostate Book, Revised Edition: The Complete Guide to Overcoming Prostate Cancer, Prostatitis, and BPH
by Peter T. Scardino M.D. (Author), Judith Kelman (Author)


Newly revised, with up-to-the-minute findings: the potentially lifesaving guide to prostate health by one of the world's foremost urologists

Although most men know little about their prostate glands, an overwhelming majority will be affected by prostate problems at some time in their lives. In this groundbreaking book, now updated to include the latest medical break-throughs, world-renowned urology expert Dr.Peter Scardino arms men with the information they need to battle prostate cancer, prostatitis, and benign prostate enlargement (BPH). This updated edition includes new information on the role genetics may play, hormone replacement therapy, new treatments for prostatitis, and more.

With clear illustrations and charts throughout, this book covers everything men should...

© 2014 BrightSurf.com