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Firefighters face increased risk for certain cancers

November 10, 2006

CINCINNATI - University of Cincinnati (UC) environmental health researchers have determined that firefighters are significantly more likely to develop four different types of cancer than workers in other fields.

Their findings suggest that the protective equipment firefighters have used in the past didn't do a good job in protecting them against cancer-causing agents they encounter in their profession, the researchers say.

The researchers found, for example, that firefighters are twice as likely to develop testicular cancer and have significantly higher rates of non-Hodgkin's lymphoma and prostate cancer than non-firefighters. The researchers also confirmed previous findings that firefighters are at greater risk for multiple myeloma.

Grace LeMasters, PhD, Ash Genaidy, PhD, and James Lockey, MD, report these findings in the November edition of the Journal of Occupational and Environmental Medicine. The UC-led study is the largest comprehensive study to date investigating cancer risk associated with working as a firefighter.

"We believe there's a direct correlation between the chemical exposures firefighters experience on the job and their increased risk for cancer," says LeMasters, professor of epidemiology and biostatistics at UC.

Firefighters are exposed to many compounds designated as carcinogens by the International Agency for Research on Cancer (IARC)-including benzene, diesel engine exhaust, chloroform, soot, styrene and formaldehyde, LeMasters explains. These substances can be inhaled or absorbed through the skin and occur both at the scene of a fire and in the firehouse, where idling diesel fire trucks produce diesel exhaust.

"Firefighters work in an inherently dangerous occupation on a daily basis," LeMasters adds. "As public servants, they need-and deserve-additional protective measures that will ensure they aren't at an increased cancer risk."

The UC-led team analyzed information on 110,000 firefighters, most of them full-time, white male workers, from 32 previously published scientific studies to determine the comprehensive health effects and correlating cancer risks of their profession.

Risk for 20 different cancers was classified into three categories-probable, possible or not likely-patterned after the IARC's risk-assessment model.

UC epidemiologists found that half the studied cancers-including testicular, prostate, skin, brain, rectum, stomach and colon cancer, non-Hodgkin's lymphoma, multiple myeloma and malignant melanoma-were associated with firefighting on varying levels of increased risk.

"There's a critical and immediate need for additional protective equipment to help firefighters avoid inhalation and skin exposures to known and suspected occupational carcinogens," says Lockey, professor of environmental health and pulmonary medicine at UC. "In addition, firefighters should meticulously wash their entire body to remove soot and other residues from fires to avoid skin exposure."

University of Cincinnati