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Women with rheumatoid arthritis have significantly less chance of remission than men
December 07, 2006Sex - A major predictor of remission in early rheumatoid arthritis?
Women with rheumatoid arthritis have significantly less chance of remission than men, finds research published ahead of print in the Annals of the Rheumatic Diseases.
The authors base their findings on almost 700 adults who had been recently diagnosed with rheumatoid arthritis.
Their average age was 58, and they had had their disease for an average of six months. Two thirds of study participants were women, and they tended to be younger than the men.
After two years, the disease had gone into remission in just under four out of 10 study participants. After five years, the proportion in remission was similar, at 38.5%. But only around one in five were in remission at both time points.
Gender was a significant factor in the progress of the disease. At two years, just under a third of the women (32%) were in remission compared with almost half of the men (48%).
By five years, the gap had widened, with just under 31% of women in remission compared with 52% of the men.
Men were more than twice as likely to be in remission as women at both time points.
Women did not have more severe disease than the men initially, but it quickly became more severe and progressed more rapidly than it did among the men.
Differences in how long a person had had the disease, their age, or their drug treatment could not explain the discrepancy in remission rate, say the authors.
BMJ Specialty Journals
Their average age was 58, and they had had their disease for an average of six months. Two thirds of study participants were women, and they tended to be younger than the men.
After two years, the disease had gone into remission in just under four out of 10 study participants. After five years, the proportion in remission was similar, at 38.5%. But only around one in five were in remission at both time points.
Gender was a significant factor in the progress of the disease. At two years, just under a third of the women (32%) were in remission compared with almost half of the men (48%).
By five years, the gap had widened, with just under 31% of women in remission compared with 52% of the men.
Men were more than twice as likely to be in remission as women at both time points.
Women did not have more severe disease than the men initially, but it quickly became more severe and progressed more rapidly than it did among the men.
Differences in how long a person had had the disease, their age, or their drug treatment could not explain the discrepancy in remission rate, say the authors.
BMJ Specialty Journals
Rheumatic Diseases Current Events and Rheumatic Diseases News RSSNew therapy for vasculitis will help patients avoid infertility and cancer
Researchers have identified that Rituxan, a drug previously approved for the treatment of non-Hodgkin's B cell lymphoma and rheumatoid arthritis, can treat severe ANCA-associated vasculitis as effectively as cyclophosphamide, the current standard therapy.
Stanford study identifies cellular mechanism that causes lupuslike symptoms in mice
Macrophages, the scavenger cells of the body's immune system, are responsible for disposing of dying cells. Stanford University School of Medicine researchers have identified one pathway in this important process in mice that, if disrupted, causes a lupuslike autoimmune disease.
Winter- and spring-onset RA patients have worse 6 month outcomes than those with summer onset
When a patient's first symptoms of rheumatoid arthritis (RA) occur in winter, the severity of their RA (as measured by the modified Total Sharp Score, mTSS, an assessment of erosion and joint space narrowing) was rated more severe at six months, when compared to patients whose RA first became symptomatic in summer (Odds Ratio (OR) =2.82 [1.14;7], p=0.0255).
Better access to info and dialogue with HCPs on sexual issues for rheumatology patients
Patients with rheumatic diseases want more information and better communication with healthcare professionals on the sexual issues related to their conditions.
Subclinical markers predict relapse in juvenile idiopathic arthritis post methotrexate withdrawal
Elevated levels of the inflammatory biomarkers Myeloid Related Protein (MRP) 8/14 predict an increased risk of relapse following withdrawal of methotrexate (MTX) therapy in children with juvenile idiopathic arthritis (JIA) who have achieved inactive disease status.
No justification for denying obese patients knee replacements
There is no justification for denying obese patients knee replacement surgery: They benefit almost as much as anyone else from the procedure, concludes a small study published ahead of print in the Annals of the Rheumatic Diseases.
Heavy birthweight babies twice as likely to develop rheumatoid arthritis
Heavy birthweight female babies are twice as likely to develop rheumatoid arthritis in adulthood as their average birthweight peers, suggests research published ahead of print in the Annals of the Rheumatic Diseases.
Heavy birthweight increases risk of developing rheumatoid arthritis
People who have a birthweight over 10 pounds are twice as likely to develop rheumatoid arthritis when they are adults compared to individuals born with an average birthweight.
Regular tipple may curb risk of rheumatoid arthritis
Alcohol cuts the risk of developing rheumatoid arthritis by up to 50%, reveals research published ahead of print in the Annals of the Rheumatic Diseases.
Women who breastfeed for more than a year halve their risk of rheumatoid arthritis
Women who breast feed for longer have a smaller chance of getting rheumatoid arthritis, suggests a study published online ahead of print in the Annals of the Rheumatic Diseases.
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