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Study finds obese patients fair better than lean patients when hospitalized for acute heart failure
January 10, 2007
Further evidence of the 'obesity paradox' FINDINGS: Researchers report that for patients hospitalized with acute heart failure, a higher body mass index (BMI) was associated with a substantially lower in-hospital mortality rate. For every 5-unit increase in body mass, the odds of risk-adjusted mortality fell 10 percent. The finding held when adjusted for age, sex, blood urea nitrogen, blood pressure, and additional prognostic factors.
IMPACT: The finding offers more insight into an observed phenomenon in chronic heart failure called the 'obesity paradox.' This is the first study to document that this inverse relationship with BMI holds in the setting of acute hospitalization for heart failure. Further study is required but the finding suggests that nutritional/metabolic support may have therapeutic benefit in specific patients hospitalized with heart failure.
BACKGROUND: The study found that by weight category, in-hospital mortality rate was 6.3 percent for underweight, 4.6 percent for healthy weight, 3.4 percent for overweight and 2.4 percent for obese patients. "The study suggests that overweight and obese patients may have a greater metabolic reserve to call upon during an acute heart failure episode, which may lessen in-hospital mortality risk," said Fonarow. Obesity is a known risk factor for developing heart disease and heart failure and every effort should be made to avoid it, but once heart failure has manifested, this paradox seems to occur. Researchers utilized data on over 100,000 acute heart failure patient episodes, taken from the Acute Decompensated Heart Failure National Registry (ADHERE). The study and ADHERE is funded by Scios, Inc. The authors have received research grants and served as consultants for Scios.
University of California-Los Angeles
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Success with Heart Failure (mass mkt ed): Help and Hope for Those with Congestive Heart Failure
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Up-to-date information on available and forthcoming medical and surgical treatments. How attitude and emotion affect heart failure--and what you can do to stay positive. Tips for adopting a heart-healthy diet and lifestyle. Ways to forge a positive working relationship with your doctor or cardiologist.
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The Cleveland Clinic Guide to Heart Failure (Cleveland Clinic Guides)
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Expert medical advice from the #1 heart center in America for 14 years in a row For the 5 million people with heart failure, there’s new reason for hope: recent medical advances have revolutionized how this condition is managed. In The Cleveland Clinic Guide to Heart Failure, Dr. Randall Starling, one of the foremost authorities on heart health, provides authoritative advice to help people survive heart failure and enjoy a good quality of life. This comprehensive resource gives readers the cutting-edge medical guidance Dr. Starling offers his patients, including: * Insight into what causes heart failure * The latest breakthrough studies – and what those discoveries mean for the future of this disease * Reliable guidance on diagnostic tests and treatment...
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This Second Edition of Dr. Katz's highly acclaimed text has been thoroughly revised to incorporate the latest advances in the study and treatment of heart failure. The book explains the pathophysiology, molecular mechanisms, clinical manifestations, and therapy of heart failure in an integrated, reader-friendly manner that is accessible to both clinicians and basic scientists. More than 100 illustrations, most created for this book by the authors, complement the text. This edition has been completely reorganized. Chapters describe the hemodynamic basis for the clinical manifestations of heart failure; the neurohumoral responses in heart failure and key signaling pathways that mediate functional responses; the proliferative responses in failing hearts; the cellular and molecular...
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Heart Failure
Heart failure, also called congestive heart failure, is a condition in which the heart cannot pump enough oxygenated blood to meet the needs of the body?s other organs. The heart keeps pumping, but not as efficiently as a healthy heart. Usually, the loss in the heart?s pumping action is a symptom of an underlying heart problem. Heart failure affects nearly 5 million US adults. It is on the rise with an estimated 400,000 to 700,000 new cases each year. This talk will focus on the causes, symptoms, diagnosis and treatments available for heart failure, including current research findings from Stanford.
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Holy Heart Failure
by Holy Heart Failure
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Heart Failure: A Practical Approach to Treatment
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The definitive one-stop guide to treating -- and preventing -- heart failure This practical reference provides all the expert guidance and up-to-the-minute clinical perspectives you need to diagnose, treat, and manage patients with heart failure. A major focus of the book is integration of various management approaches to maximize patient benefit. Coverage begins with a brief introduction to the incidence and causes of heart failure, then quickly moves into a more thorough clinical overview of symptom evaluation, pharmacologic and non-pharmacologic treatment methods, hospitalization, surgical treatments, and more. Features: Clear, step-by-step coverage of prevention and all treatment modalities with evidence-based recommendations Full...
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Pathophysiology For Nurses: Heart Failure and Pulmonary Edema (VHS)
Also With: Mosby (Producer)
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