New guidelines issued for diagnosis and management of venous thromboembolismJanuary 30, 2007Recommendations are a joint effort of the American Academy of Family Physicians and the American College of Physicians LEAWOOD, Kan. - The American Academy of Family Physicians (AAFP) and American College of Physicians (ACP) today released new clinical practice guidelines for the diagnosis and management of venous thromboembolism (VTE). Key elements of the diagnosis guideline include the use of clinical prediction rules to establish pretest probability of deep vein thrombosis or pulmonary embolism in a patient before further testing and the utility of various diagnostic tools such as D-dimer and ultrasonography. The management guideline supports the use of low-molecular weight heparin for patients with deep vein thrombosis in the outpatient setting when appropriate support services are in place. Each guideline contains several recommendations to aid in the diagnosis and treatment of lower extremity deep venous thrombosis and pulmonary embolism. A thromboembolism occurs when a blood clot, formed at one point in the circulatory system, detaches and obstructs circulation at another point. A pulmonary embolism occurs when such a clot, usually originating in the veins of the leg, obstructs the pulmonary artery or one of its branches. A large embolus may result in acute heart failure or sudden death. More than 200,000 deaths each year are associated with VTE in the United States. The Annals of Family Medicine and Annals of Internal Medicine have joined in publishing the new guidelines. Both guidelines and an evidence review for the diagnosis guideline are published in this issue of Annals of Family Medicine. The management guideline is being published at www.annals.org on Monday, Jan. 29, at 6 p.m. EST. The management guideline and companion evidence review will be published in the Feb. 6, 2007, issue of Annals of Internal Medicine. The new diagnosis guideline targets primary care physicians who are most likely to have frontline contact with patients who have not yet been diagnosed. The guideline aims to present evidence-based recommendations for diagnosis of lower extremity DVT and pulmonary embolism. "These new guidelines represent a collaborative effort between family medicine and internal medicine," said Rick Kellerman, M.D., AAFP president. "We are pleased to collaborate with the American College of Physicians on this endeavor to provide physicians with the tools they need to prevent mortality and morbidity associated with venous thromboembolism." Incidence rates for VTE are higher in men, African-Americans, and increase substantially with age. Treating VTE at an early stage can avoid complications such as pulmonary embolism or recurrent DVT. "ACP has been producing evidence-based clinical practice guidelines since 1981 to help physicians provide the best health care possible, based on the best available current evidence," said Amir Qaseem, MD, PhD, MHA, senior medical associate in the Clinical Programs and Quality of Care department of the Medical Education and Publishing Division at the American College of Physicians. "These guidelines provide information on the utility of various diagnostic tools and compare the efficacy and safety of various pharmacologic agents used for treatment of VTE." American Academy of Family Physicians |
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| Related Thromboembolism Current Events and Thromboembolism News Articles Menopause-cardiology consensus statement on cardiovascular disease and on HRT A menopause-cardiology consensus statement has called for direct action to prevent cardiovascular disease (CVD) in menopausal women. The statement also concludes that there is little evidence of increased CVD risk in taking HRT. Drugs to treat anemia in cancer patients linked to thromboembolism Medications frequently given to cancer patients to reduce their risk of anemia are associated with an increased risk of deep vein thrombosis or pulmonary embolism, according to new research led by Dawn Hershman, M.D, M.S., co-director of the breast cancer program at the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian Hospital/Columbia University Medical Center. Study of adjuvant endocrine treatment for breast cancer reveals cost of noncompliance The largest study in the world of treatments for post menopausal, hormone positive breast cancer has shown that patients who continue to take exemestane or tamoxifen do significantly better than patients who start to take one or other drug (or tamoxifen followed exemestane) but then stop. Elevated level of certain protein in urine linked to increased risk for blood clots Preliminary research suggests that higher than normal levels of the protein albumin in urine is associated with an increased risk for blood clots in the deep veins of the legs or lungs (venous thromboembolism; VTE), according to a study in the May 6 issue of JAMA. New study suggests Rx estrogen delivery through the skin may show safety benefits as opposed to oral delivery Transdermal delivery of estrogen therapy available by prescription "seems not to alter" the risk of venous thromboembolism (VTE), or blood clotting, in postmenopausal patients when compared to oral delivery, a new study suggests. Study shows optimal dose management of warfarin improves anticoagulation control Researchers from Boston University School of Medicine (BUSM) have determined the optimal dose-management strategy to derive maximal benefit from warfarin therapy and improve patient outcomes. Results of the study appear online in the December 2008 issue of the Journal of Thrombosis and Haemostasis. Research highlights new approaches to prevent blood clots Blood clotting, or coagulation, is an important process that prevents excessive bleeding when a blood vessel is injured. Women may stop anticoagulants after blood clots Women may safely discontinue oral anticoagulants (blood thinners) after 6 months of treatment following a first unprovoked venous blood clot (thromboembolism) if they have no or one risk factor. Maternal deaths following cesarean delivery can be reduced Maternal death rates have remained constant in the United States for many decades. Are there any improvements in health care that could reduce these rates further? New blood clot guidelines for pregnant women New evidence-based guidelines address the prevention and management of thrombosis in key patient populations and reinforce recommendations related to the routine use of preventive therapies. More Thromboembolism Current Events and Thromboembolism News Articles |
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