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Early life growth spurts protect against 'bad' cholesterol
March 02, 2007Tall toddlers and rapidly growing teens are likely to find themselves with lower cholesterol, particularly the "bad" type, in later life, suggests research in the Journal of Epidemiology and Community Health.
Conversely, piling on the pounds after the age of 15 boosted cholesterol levels, the study showed.
The findings are based on just under 3000 participants of a Medical Research Council long term study, tracking a representative sample of 5362 people born in one week of March in 1946.
Heights and weights were measured at the ages of 2, 4, 7, 15, 36 and 53. When participants reached the age of 53, blood samples were taken to measure cholesterol levels.
When all the figures were analysed, the results showed that the faster height was gained before the age of 2, and after the age of 15, the lower was the cholesterol level at the age of 53.
Growth in leg length, rather than trunk length, was more strongly associated with lower cholesterol levels.
Higher body fat levels at the ages of 36 and 53, and more rapid weight gain between the ages of 15 and 53, were associated with higher total cholesterol levels, including higher levels of the harmful low density lipoprotein (LDL) cholesterol.
The researchers found that the effects of the growth spurts in either height or girth could not be explained by weight at birth, which is a well known factor in adult health, or lifetime socioeconomic status.
BMJ Specialty Journals
Heights and weights were measured at the ages of 2, 4, 7, 15, 36 and 53. When participants reached the age of 53, blood samples were taken to measure cholesterol levels.
When all the figures were analysed, the results showed that the faster height was gained before the age of 2, and after the age of 15, the lower was the cholesterol level at the age of 53.
Growth in leg length, rather than trunk length, was more strongly associated with lower cholesterol levels.
Higher body fat levels at the ages of 36 and 53, and more rapid weight gain between the ages of 15 and 53, were associated with higher total cholesterol levels, including higher levels of the harmful low density lipoprotein (LDL) cholesterol.
The researchers found that the effects of the growth spurts in either height or girth could not be explained by weight at birth, which is a well known factor in adult health, or lifetime socioeconomic status.
BMJ Specialty Journals
Cholesterol News and Current Cholesterol Events RSSNew mushroom study shows the power of energy density
Preliminary research, led by Dr. Lawrence Cheskin, MD, Director of John Hopkins Weight Management Center, suggests increasing intake of low-energy density foods, specifically mushrooms, in place of high-energy-density foods, like lean ground beef, is a strategy for preventing or treating obesity.
Researchers find cancer-inhibiting compound under the sea
University of Florida College of Pharmacy researchers have discovered a marine compound off the coast of Key Largo that inhibits cancer cell growth in laboratory tests, a finding they hope will fuel the development of new drugs to better battle the disease.
Obesity genes revealed
A study of 228 women has revealed genetic variants responsible for body shape. Based on work in the fruit fly Drosophila melanogaster, research published today in the open access journal BMC Genetics identifies natural variation in the human LAMA5 gene as a key determinant of weight.
Adults who eat eggs for breakfast lose 65 percent more weight
A study published online today in the International Journal of Obesity shows that eating two eggs for breakfast, as part of a reduced-calorie diet, helps overweight adults lose more weight and feel more energetic than those who eat a bagel breakfast of equal calories.
Exercise Pill is No Replacement for Exercise
Recently, researchers at the Salk Institute for Biological Studies, a research organization focused on biology and its relation to health, published a study in the journal Cell on the results of a substance that increased exercise endurance without daily exertion when tested in mice.
Lowering cholesterol early in life could save lives
With heart disease maintaining top billing as the leading cause of death in the United States, a team of University of California, San Diego School of Medicine physician-researchers is proposing that aggressive intervention to lower cholesterol levels as early as childhood is the best approach available today to reducing the incidence of coronary heart disease.
Long-term HIV treatment may reduce risk for atherosclerosis
Antiretroviral drugs for HIV do not increase the risk for coronary atherosclerosis, a central risk factor for heart disease, according to a study led by the University of Pittsburgh Graduate School of Public Health to be published in the Aug. 8 issue of the journal AIDS and available online today.
2 years old -- a childhood obesity tipping point?
Over the last decade, childhood obesity has grown into an epidemic, reflected in soaring rates of type 2 diabetes and recommendations that pediatricians check toddlers for elevated cholesterol.
Growth hormone reduces abdominal fat, cardiovascular risk in HIV patients on antiviral therapy
Low-dose growth hormone treatment reduced abdominal fat deposits and improved blood pressure and triglyceride levels in a group of patients with HIV lipodystrophy, a condition involving the redistribution of fat and other metabolic changes in patients receiving combination drug therapy for HIV infection.
Growth hormone treatment for HIV patients improves abdominal fat, but worsens glucose level
For human immunodeficiency virus (HIV)-infected patients with treatment-related abdominal obesity and growth hormone deficiency, receiving low-dose growth hormone resulted in improvement in fat and blood pressure measurements but worsened glucose levels.
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