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Pioneering research into health benefits of beauty treatment
March 07, 2007Pioneering medical research is going on at the University of Leicester into the use of Botulinum toxin - commonly thought of as a beauty treatment - for bladder problems.
Dr Douglas Tincello, Senior Lecturer at the University's Department of Cancer Studies and Molecular Medicine and Consultant Gynaecologist at the Leicester General Hospital, is carrying out a randomised trial involving injecting botulinum toxin into the bladders of women who have overactive bladder disease.
The trial, which has received a grant of £158,000 from the Moulton Charitable Trust, involves women whose conditions have not improved after tablet treatment.
Overactive bladder is a condition in which the bladder tries to empty itself, rather than the patient retaining control. Symptoms include having to pass water very often day and night, not being able to put off the need to do so, sudden urgency to pass water and sometimes incontinence.
The botulinum toxin relaxes the bladder muscle so it cannot squeeze so hard, and so reduces the need to pass water frequently or suddenly. It may also reduce the sensation of having a full bladder. Dr Douglas Tincello commented:
"Overactive bladder is very difficult to treat well. Lots of our patients try different tablets and pelvic floor exercises but at least a third of them will not be better. At the moment the only alternatives are to put up with it, or consider a very big operation which often means the patient ends up with a stoma bag.
"Many patients just suffer in silence, but the quality of life when you live with overactive bladder is similar to that of a patient on kidney dialysis.
"Botulinum toxin has been tested already in spinal cord injury patients.This study is important to ascertain if it is safe and effective in patients with overactive bladder. Botulinum toxin is a very exciting development and in the future may provide a simple and effective way to improve the quality of life in our patients.\\\
University of Leicester
Overactive bladder is a condition in which the bladder tries to empty itself, rather than the patient retaining control. Symptoms include having to pass water very often day and night, not being able to put off the need to do so, sudden urgency to pass water and sometimes incontinence.
The botulinum toxin relaxes the bladder muscle so it cannot squeeze so hard, and so reduces the need to pass water frequently or suddenly. It may also reduce the sensation of having a full bladder. Dr Douglas Tincello commented:
"Overactive bladder is very difficult to treat well. Lots of our patients try different tablets and pelvic floor exercises but at least a third of them will not be better. At the moment the only alternatives are to put up with it, or consider a very big operation which often means the patient ends up with a stoma bag.
"Many patients just suffer in silence, but the quality of life when you live with overactive bladder is similar to that of a patient on kidney dialysis.
"Botulinum toxin has been tested already in spinal cord injury patients.This study is important to ascertain if it is safe and effective in patients with overactive bladder. Botulinum toxin is a very exciting development and in the future may provide a simple and effective way to improve the quality of life in our patients.\\\
University of Leicester
Botulinum Toxin Current Events and Botulinum Toxin News RSSBotulinum toxin injection may help prevent some types of migraine pain
A preliminary study suggests the same type of botulinum injection used for cosmetic purposes may be associated with reduced frequency of migraine headaches that are described as crushing, vicelike or eye-popping (ocular), but not pain that is experienced as a buildup of pressure inside the head.
Can blocking a frown keep bad feelings at bay?
Your facial expression may tell the world what you are thinking or feeling. But it also affects your ability to understand written language related to emotions, according to research that was presented today to the Society for Personal and Social Psychology in Las Vegas, and will be published in the journal Psychological Science.
Anti-spasticity medications need further research
Only a few anti-spasticity medications used for children with cerebral palsy are backed by sufficient research to justify their use, according to a new review of scientific literature headed by a UT Southwestern Medical Center neurologist and conducted by a national panel of interdisciplinary experts nationwide.
New guidelines identify best treatments to help ALS patients live longer, easier
New guidelines from the American Academy of Neurology identify the most effective treatments for amyotrophic lateral sclerosis (ALS), often called Lou Gehrig's disease. The guidelines are published in the October 13, 2009, issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers find demand for cosmetic and surgical procedures in dermatologic surgery rising rapidly
Researchers from Boston University School of Medicine (BUSM) and the Laser and Skin Cancer Center of Indiana, (Carmel, Indiana), found that there has been a dramatic increase in the number of procedures performed and patient demand for dermatologic health care since 2000.
American Pain Society's low back guideline expanded to cover interventional procedures
For low-back pain patients and their doctors, the American Pain Society, www.ampainsoc.org, said today it is expanding its evidence-based, clinical practice guideline on diagnosis and treatment of chronic low back pain to include recommendations on surgery and other interventional treatments.
Researchers develop new ultrasensitive assay to detect most poisonous substance known
Scientists at City of Hope and the California Department of Public Health have developed a new ultrasensitive assay to detect botulinum neurotoxin.
Botox for newborns
Botulinum toxin, also called Botox, is best known as one of the most commonly used molecules to reduce wrinkles. It is also known as one of the most poisonous naturally occurring substances.
Urologist uses Botox to treat debilitating condition
Eight years ago, Lynette Kunz suffered a severe spinal cord injury that left her a quadriplegic and sufferer of involuntary bladder contractions. The condition constantly interfered with her daily life.
UT Southwestern urologist uses Botox to treat debilitating condition
Eight years ago, Lynette Kunz suffered a severe spinal cord injury that left her a quadriplegic and sufferer of involuntary bladder contractions. The condition constantly interfered with her daily life.
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Procedures in Cosmetic Dermatology Series: Botulinum Toxin with DVD by Alastair Carruthers MA BM BCh FRCP(LON) FRCPC (Author), Jean Carruthers MD FRCSC (Author) This title in the PROCEDURES IN COSMETIC DERMATOLOGY SERIES presents up-to-the-minute, practical guidance on botulinum toxin injection techniques shaping today's practice. Succinctly written and lavishly illustrated, it focuses on procedural how-to's and offers step-by-step advice on proper techniques, pitfalls, and tricks of the trade-so you can refine and hone your skills...and expand your surgical repertoire. You'll find current, to-the-point guidance on the cosmetic use of the toxin - edited by pioneers in the field, Drs. Jean and Alastair Carruthers. Implement the newest procedures into your practice immediately and confidently-with the outstanding guidance you'll find in this volume of the PROCEDURES IN COSMETIC DERMATOLOGY SERIES. Covers the hottest topics-including botox... |
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Botulinum Toxin Injection Guide by Lb (Author), M.D. Odderson (Author) Botilinum toxin is used frequently by physiatrists for the treatment of patients with migraines, tics, spasms, dystonia, hyperhidrosis (excessive sweating), and pain. Botulinum Toxin Injection Guide by Ib R. Odderson, MD, PhD, is the first comprehensive manual that covers botulinum toxin injections for neurologic conditions and their wide range of practical applications. |
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Pretox 20 (1) 1.7 oz. Injection-Free alternative to Botulinum Toxin by Medik8 Injection-Free alternative to Botulinum Toxin treatment. Muscle Relaxant Gel in Liposome Delivery System. Muscles contract when they receive a neurotransmitter release from a nerve. Like Botulinum Toxin A, Pretox releases the amount of nerve stimulation on the local muscle tissue being targeted but unlike Botulinum Toxin A, Pretox does not paralyse the muscle completely. Instead it gently and temporarily reduces the strength of specific muscle contractions thus the formulation of new lines and wrinkles in reduced and old lines appear much less prominent - leaving you with smoother younger looking skin. |
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Manual of Botulinum Toxin Therapy (Cambridge Medicine) by Daniel Truong (Editor), Dirk Dressler (Editor), Mark Hallett (Editor) The Manual of Botulinum Toxin Therapy provides practical guidance on the use of botulinum toxin in a wide variety of disorders, in many areas of medicine. Using clear line drawings, it describes the relevant injection sites for each condition and gives comparative dosage tables for the various formulations of toxin used in different muscle groups. It also provides the most up-to-date review of the range of applications, including coverage of promising future developments. The emphasis throughout is on technique. This book can be read as a teaching aid, and will also be useful for immediate bedside guidance. This Manual will be of interest to the growing band of clinicians discovering the potential of botulinum toxin, including neurologists, otolaryngologists, urologists,... |
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Botulinum Toxin in the Management of Facial Spasm [VHS] | |
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Making it New Again: Laser Scar Revision and Facial Rejuvenation This talk will focus on new treatments for reducing, and in some cases, eliminating scars from acne and other imperfections in the skin through the use of the newest laser technology. This product is manufactured on demand using DVD-R recordable media. Amazon.com's standard return policy will apply. |
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Botulinum Toxin: Therapeutic Clinical Practice and Science, Expert Consult - Online and Print by Joseph Jankovic MD (Author), Alberto Albanese (Author), M. Zouhair Atassi PhD DSc (Author), J. Oliver Dolly (Author), Mark Hallett MD (Author), Nathaniel H. Mayer (Author) The new, therapeutically-focused Botulinum Toxin presents comprehensive, cross-disciplinary guidance on current practices, covering more than 100 non-cosmetic conditions that occur in neurology, physical medicine and rehabilitation, pain medicine, ophthalmology, gastroenterology, urology, orthopedics, and surgery. International contributors review the current understanding of the biology and cellular mechanisms along with relevant research so you can easily apply them to the pathophysiology of the numerous disorders that botulinum toxin is used to treat-such as botulinum toxin applications for the treatment of cranial-cervical dystonias, motor disorders in cerebral palsy, bruxism and temporomandibular disorders, headache, overactive bladder, chronic pelvic pain syndromes, arthritis joint... |
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Pictorial Atlas of Botulinum Toxin Injection: Dosage, Localization, Application by Wolfgang Jost (Author), MD (Author), in collaboration with Klaus-Peter Valerius (Author) Within the last 20 years, the use of local injection with botulinum toxin has proven to be effective in the treatment of increased tonicity in both skeletal and smooth muscle as well as in illnesses presenting with increased secretion from glands. Following local injection, the botulinum toxin reduces muscle tone effectively for several months and also reduces secretion from sweat, lachrymal, and salivary glands. Botulinum toxin has influenced therapy in neurology like no other substance, and it is now considered the drug of choice for treatment of cervical dystonia, blepharospasm, and hemifacial spasm.
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Handbook of Botulinum Toxin Treatment by A. P. Moore (Editor), Markus Naumann (Editor) The Walton Centre for Neurology and Neurosurgery, Liverpool, UK. Text provides up-to-date advancements and development of the established and newer uses for botulinum toxin A. Includes historical information and the different conditions treated with botulinum toxin. Previous edition: c1995. DNLM: Botulinum Toxins--therapeutic use. |
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Botulinum Toxin in Aesthetic Medicine by Mauricio Maio (Author), Berthold Rzany (Author) Written by two renowned international experts in the field, this book gives a brilliant overview of the use of botulinum toxin A in aesthetic medicine, including patient selection and evaluation, as well as rules and requirements. It provides hands-on information for the most common indications, such as forehead and glabella, lateral brow lift, crow’s feet and lower eyelid, bunny lines and marionette lines, nose and nasolabial folds, cheeks and "gummy smile," upper and lower lip, and the chin and neck. Also included are the more advanced indications, such as facial asymmetries, Btx-A lifting and microinjection techniques. Combination therapy and complications are also covered and a section with tips and tricks makes this book an invaluable resource for the... |
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