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Study shows that anal cytology predicts anal precancer in HIV-positive gay men
March 22, 2007UCLA Center for Clinical AIDS Research and Education is one of only a few US centers offering an anal cytology screening service
FINDINGS: HIV-positive men who have sex with men are up to 90 times more likely than the general population to develop anal cancer. Detection of precancerous changes (anal dysplasia) by anal cytology — essentially an anal canal Pap smear — is a relatively new procedure and one that has yet to enter standard practice.
This UCLA study demonstrated that abnormal anal cytology was highly predictive of anal cell abnormalities that were subsequently confirmed by anal biopsy. The study was based on data from 244 patients at the UCLA CARE clinic who had anal cytology screenings between February 2002 and December 2004.
IMPACT: Abnormal anal cytology in HIV-positive men who have sex with men is highly indicative of the presence of abnormal anal cells that may be precancerous and should prompt further investigation. The UCLA CARE Center is one of a handful of clinics in the United States offering an anal dysplasia screening and management service.
AUTHORS: Ross D. Cranston, Steven.D. Hart , Jeffrey A. Gornbein, Sharon L. Hirschowitz, Galen Cortina, and Ardis.A. Moe, all of UCLA.
JOURNAL: The research appears in the February issue of the International Journal of STD & AIDS.
University of California-Los Angeles
IMPACT: Abnormal anal cytology in HIV-positive men who have sex with men is highly indicative of the presence of abnormal anal cells that may be precancerous and should prompt further investigation. The UCLA CARE Center is one of a handful of clinics in the United States offering an anal dysplasia screening and management service.
AUTHORS: Ross D. Cranston, Steven.D. Hart , Jeffrey A. Gornbein, Sharon L. Hirschowitz, Galen Cortina, and Ardis.A. Moe, all of UCLA.
JOURNAL: The research appears in the February issue of the International Journal of STD & AIDS.
University of California-Los Angeles
Cytology Current Events and Cytology News RSSVaccination and testing for the human papilloma virus could eradicate cervical cancer
Cervical cancer could be eradicated within the next 50 years if countries implement national screening programmes based on detection of the human papilloma virus (HPV), which causes the disease, together with vaccination programmes against the virus, according to a cervical cancer screening expert.
Mayo Clinic finds new pathology tests double sensitivity to detect bile duct and pancreatic cancers
Pancreatic cancer and bile duct cancer are difficult to diagnose and often fatal because they are discovered in the advanced stages of the disease.
UAB researchers report breakthrough in HPV research
UAB (University of Alabama at Birmingham) researchers have developed a new, inexpensive and efficient method for producing and studying a type of human papillomavirus (HPV) that causes cervical cancer. The process could speed understanding of how the virus functions and causes diseases, and lead to new prevention or treatment options.
Bladder cancer detected via amplified gene in cells found in urine
Counting the copies of a specific gene in cells gathered from a urine sample may provide a simple, noninvasive way to detect bladder cancer, a team led by researchers at The University of Texas M. D. Anderson Cancer Center reports in the Journal of the National Cancer Institute.
New HPV test for developing countries shows high accuracy in predicting cervical disease: Study
A new HPV test developed by QIAGEN specifically for use in regions of the world with scarce resources is "substantially" more accurate in identifying women with cervical disease than the current methods (Pap testing and visual inspection) in these countries.
Endoscopic ultrasound highly accurate in evaluating ambiguous radiographic findings of the pancreas
Researchers from St. Louis University School of Medicine in Missouri report that EUS and EUS-FNA is 99.1 percent accurate in diagnosing pancreatic neoplasms (abnormal growths or tumors) in patients who were referred for endoscopic ultrasound (EUS) because of CT and/or MRI reports of two common, though somewhat ambiguous findings - enlargement of head of pancreas (HOP) or dilation of the pancreatic duct (PD).
Cervical cancer prevention should focus on vaccinating adolescent girls
The cost-effectiveness of vaccination in the United States against human papillomavirus (HPV), a sexually-transmitted virus that causes cervical cancer, will be optimized by achieving universal vaccine coverage in young adolescent girls, by targeting initial "catch-up" efforts to vaccinate women younger than 21 years of age, and by revising current screening policies.
Self-collection of specimens for HPV testing
n this Research letter, Dr. Gina Ogilvie and colleagues investigate the feasibility of self-collection of specimens for HPV testing among women who may not make full use of cytology screening programs (e.g., women who are homeless or who are involved in the sex trade) and are thus at increased risk of cervical cancer.
Simple diagnostic test detects genetic signs of lung cancer in a patient's sputum
DNA coughed up along with phlegm could point to lung cancer, say researchers at the University of Maryland School of Medicine who are developing an inexpensive and non-invasive gene probe to help diagnose early stage lung cancer in current and former smokers.
HPV test is a better long-term predictor of cervical cell abnormalities than pap smear
The best initial cervical cancer screening tool for younger women is still the traditional Pap smear. However, a large Danish study has found that for older women (age 40 and older), a test for human papillomavirus (HPV) is a much more effective way to screen for potential cancer.
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