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Prenatal exposure to glucocorticoids has long-term deleterious effects on newborns
March 23, 2007Researchers at the University of Edinburgh in the United Kingdom have found that, as for rodents and other nonprimates, prenatal exposure of nonhuman primate African vervet monkeys (Chloroceus aethiops) to glucocorticoids has long-lasting deleterious effects on cardiovascular, metabolic, and neuroendocrine function.
Glucocorticoids are still widely used in obstetric practice. So, Jonathan Seckl and colleagues set out to determine the relevance to human pregnancy of rodent and nonprimate data indicating that prenatal exposure to glucocorticoids (through either the administration of dexamethasone or severe maternal stress) has long-lasting deleterious effects. In the study, which appears online on March 22 in advance of publication in the April print issue of the Journal of Clinical Investigation, they show that although the birth weight of offspring born to nonhuman primate African vervet monkeys treated with dexamethasone from mid-gestation onward did not differ from that of offspring born to untreated animals, the high levels of prenatal dexamethasone impaired postnatal growth, impaired glucose-insulin homeostasis, increased blood pressure 12 months after birth, and increased the production of cortisol in response to mild stress. These data suggest that both repeated glucocorticoid therapy and severe maternal stress late in gestation are likely to have long-term deleterious effects on developing human fetuses.
Journal of Clinical Investigation
Prenatal Current Events and Prenatal News RSSExposure to lead, tobacco smoke raises risk of ADHD
Children exposed prenatally to tobacco smoke and during childhood to lead face a particularly high risk for ADHD, according to research done at Cincinnati Children's Hospital Medical Center.
Pilot study relates phthalate exposure to less-masculine play by boys
A study of 145 preschool children reports, for the first time, that when the concentrations of two common phthalates in mothers' prenatal urine are elevated their sons are less likely to play with male-typical toys and games, such as trucks and play fighting.
Local health investigation sheds light on gastroschisis birth defect
Results of an investigation conducted by University of Nevada, Reno researchers, public health officials and area physicians published this week in the Archives of Pediatrics & Adolescent Medicine, indicate that Washoe County experienced a cluster of a particular birth defect, gastroschisis, during the period April 2007 - April 2008.
Hormone that affects finger length key to social behavior
The hormones, called androgens, are important in the development of masculine characteristics such as aggression and strength.
Acetaminophen may be linked to asthma in children and adults
New research shows that the widely used pain reliever acetaminophen may be associated with an increased risk of asthma and wheezing in both children and adults exposed to the drug.
Pregnant women risk early delivery from using psychiatric medication
The odds triple for premature child delivery pregnant women with a history of depression who used psychiatric medication, according to a new study.
Sex-based prenatal brain differences found
Prenatal sex-based biological differences extend to genetic expression in cerebral cortices. The differences in question are probably associated with later divergences in how our brains develop.
Cocaine exposure during pregnancy leads to impulsivity in male, not female, monkeys
Adult male monkeys exposed to cocaine while in the womb have poor impulse control and may be more vulnerable to drug abuse than female monkeys, even a decade or more after the exposure, according to a new study by researchers at Wake Forest University School of Medicine. The findings could lead to a better understanding of human drug abuse.
Studies find few risks to newborn offspring of parents who are childhood cancer survivors
Whether they can have children is one of the major concerns for adult survivors of childhood and adolescent cancer because fertility can be compromised by cancer treatment.
Understanding the implications of prenatal testing for Down syndrome
New article examines the influence of current tests on birth rates, assesses forthcoming tests, and calls for the establishment of medical and educational policies.
More Prenatal Current Events and Prenatal News Articles
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Rainbow Light Just Once Prenatal One Multivitamin Tablets, 90-Count Bottle by Rainbow Light Dietary Supplement. Feel the difference: Potent & science-safe; Gentle on the stomach; Guaranteed 100% natural. Celebrating 25 years! Potent & science safe targeted nutrition for pregnant & nursing women. Prenatal One Multivitamin supports all body systems of pregnant and nursing women with: Research-backed multivitamin protection - from optimal potencies of critical nutrients including extra iron and the full 800 mcg of folic acid, plus the most optimal potencies of calcium and magnesium of any one-per-day prenatal multivitamin. A gentle prenatal blend - of nourishing botanicals, traditionally used to support a healthy pregnancy, including fresh ginger juice to help soothe digestion. Guaranteed 100% natural - for exceptional purity when moms and babies need it most. 100% natural - Free... |
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Perfect Prenatal 180 tabs by NEW CHAPTER Nature's organic probiotic whole-food prenatal vitamin promotes physical stamina and emotional well-being while nurturing mother and baby. We at New Chapter provide you an organic probiotic alternative to isolated or USP vitamins and minerals. All of our vitamins and minerals are cultured in organic soy using nature's most prized and studied probiotics, featuring Lactobacilli acidophilus, bifidus, rhamnosus, and Saccharomyces cerevisiae. New Chapter's Probiotic Nutrients deliver biotransformed vitamins and minerals in their finest cultured form, much in the same way as miso, kefir, tempeh, and yogurt. Your New Chapter nutrients: -Are easy to digest, even on an empty stomach-they're cultured whole food! -Deliver essential nutrients in their safest and most active form... |
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Rainbow Light Complete Prenatal System, Food Based, Tablets, 180 tablets by Rainbow Light Multivitamin supplement. No. 1 seller. Research-based nutrition. Protective potencies. Supports mother and baby. Scientifically advanced nutritional protection that eases the daily discomforts of pregnancy. Rainbow Light's Complete Prenatal System multivitamin nurtures mother and baby throughout pregnancy. It: Delivers Research-Based Nutrition--from protective potencies of the full range of vitamins and minerals critical to supporting a baby's healthy development and a mother's vitality, featuring 1000 mg of calcium, 800 mcg of folic acid and 30 mg of non-constipating iron; Eases Pregnancy Discomforts--such as leg cramps, swelling, nausea, heartburn and fatigue, featuring magnesium, potassium, high-potency B Vitamins and energizing green foods for targeted support; Is Gentle on the... |
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Prenatal Yoga Starring: Shiva Rea Directed By: Ted Landon Also With: Bryan H. Shepard (Cinematographer), Lori Eschler Frystak (Composer), Charlie Webber (Editor) Shows yoga modifications for the various trimesters of pregnancy. Genre: Pregnancy Workouts Rating: NR Release Date: 23-SEP-2003 Media Type: DVD |
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Prenatal DHA - 90 - Softgel by Nordic Naturals Nordic Naturals Prenatal DHA is a high concentrate DHA supplement for mood support, proper memory, and neurological function, and proper infant development. Encapsulated in small, easy-to-swallow soft gelatin capsules, Nordic Naturals Prenatal DHA is a healthy way to ensure adequate intake of the essential brain nutrient, DHA. Ingredients: purified deep sea fish oil (from anchovies and sardines), soft gel capsule (gelatin, water, glycerin), d-alpha tocopherol, rosemary extract Each 2 soft gel serving provides: DHA: 450 mg Other Omega-3s: 40 mg EPA: 90 mg Vitamin E (d-alpha tocopherol): 15 IU |
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Nature Made Prenatal Multiple Vitamin and Mineral Supplement for Pregnant or Lactating Women, 90-Count Tablets (Pack of 3) by Nature Made Nature Made Prenatal High in Folic Acid, Iron & Zinc. Complete Multi Vitamin/Mineral Supplement. 90 Premium Tablets. |
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10 Minute Solution: Prenatal Pilates Starring: Lizbeth Garcia No Time To Exercise? We have the solution for you – the 10 Minute Solution! Everyone can find at least ten minutes in their day, and we’ve developed 5 dynamic workouts that are just 10 minutes each. The workouts were designed to help you stay fit and healthy throughout your pregnancy. These compact workouts fit into even the busiest of schedules. Split them into 5 separate workouts or do them all together for one amazing, prenatal Pilates workout! Highlighted in the August 16th, 2007 issue of The New York Times, this DVD will allow you to modify your workouts to your pregnant body. Pilates For Buns & Thighs: Get ready to strengthen your lower body and get toned, firm thighs and buns – even as your belly continues to get bigger. Standing Pilates: For this segment, instructor... |
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Prenatal Plus DHA Complete 16 Ounces by Buried Treasure PreNatal Plus DHA Complete - offers women (before conception, during pregnancy, and while nursing) a comprehensive solution for all their babies' special nutritional requirements. Designed for the Special Nutritional Needs of the Mother-To-Be |
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Spring Valley - Prenatal Multivitamin, 240 Tablets by Leiner Health Products, LLC. Prenatal is formulated to supplement overall nutritional needs for the general well being of pregnant or lactating women. A balanced intake of essential vitamins and minerals is necessary for good health. |
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Mozart for Mothers-To-Be: Tender Lullabies for Mother and Child Eva Czako (Performer), Wolfgang Amadeus Mozart (Performer), Alexander Gibson (Performer), Neville Marriner (Performer), Academy of St. Martin-in-the-Fields (Performer), Academy of St. Martin-in-the-Fields (Performer), Academy of St. Martin-in-the-Fields Chamber Ensemble (Performer), Grumiaux Trio (Performer), Quartetto Italiano (Performer), New Philharmonia Orchestra (Performer), Georges Janzer (Performer), Max Lesueur (Performer), Arpad Gerecz (Performer), Arthur Grumiaux (Performer) |
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