 |
|
Harvard and U. Pittsburgh researchers explain carbon monoxide's anti-inflammatory effects
March 30, 2007In a study appearing in the April 2007 issue of The FASEB Journal, scientists from Harvard University and the University of Pittsburgh have shown for the first time that the anti-inflammatory effects of carbon monoxide originate within cells' own molecular engines, mitochondria. Specifically, mitochondria react to low levels of carbon monoxide by releasing chemical signals that reduce or shut down the body's inflammatory response, raising the possibility for the development of new anti-inflammatory therapies, one of which may be low levels of inhaled carbon monoxide.
According to the study's first author, Brian S. Zuckerbraun, M.D. of the University of Pittsburgh, "this study may contribute to our understanding and development of controlled carbon monoxide as a therapeutic agent."
Inflammation is a normal defense mechanism used by the body to ward off infection, but over time, severe or chronic inflammation can damage tissues. In some cases, such as in organ transplantation, the body's inflammatory response over the short-term also can cause more harm than good. Current approaches to controlling inflammation are not always successful, making the need for new approaches urgent. In particular, inhaled medical grade carbon monoxide has been shown to be useful in animal models for organ transplantation, vascular injury, inflammatory bowel disease, organ injury resulting from severe blood loss, as well as experimental hepatitis and experimental pulmonary hypertension.
"The findings described in this study are particularly relevant, given that April is National Donate Life Month," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "Transplants are rejected because of inflammation gone awry. If we block inflammation, as with carbon monoxide or agents that release it in a controlled fashion, we can not only make transplantation safer, but extend its benefits to many more who need it."
Federation of American Societies for Experimental Biology
"The findings described in this study are particularly relevant, given that April is National Donate Life Month," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "Transplants are rejected because of inflammation gone awry. If we block inflammation, as with carbon monoxide or agents that release it in a controlled fashion, we can not only make transplantation safer, but extend its benefits to many more who need it."
Federation of American Societies for Experimental Biology
Carbon Monoxide Current Events and Carbon Monoxide News RSSAir pollution increases infants' risk of bronchiolitis
Infants who are exposed to higher levels of air pollution are at increased risk for bronchiolitis, according to a new study.
Breakthrough in industrial-scale nanotube processing
Rice University scientists today unveiled a method for the industrial-scale processing of pure carbon-nanotube fibers that could lead to revolutionary advances in materials science, power distribution and nanoelectronics.
Interactions with aerosols boost warming potential of some gases
For decades, climate scientists have worked to identify and measure key substances -- notably greenhouse gases and aerosol particles -- that affect Earth's climate.
For safer emergencies, give your power generator some space
To subdue the steaming heat of hurricanes or to thaw out during a blizzard, gasoline-powered, portable generators are a lifeline during weather emergencies when homes are cut off without electricity.
Research gives new meaning to 'green' cross code
Pedestrians could reduce the amount of traffic pollution they breathe in simply by crossing the street, according to the latest research from the University of Leeds.
New stove dramatically improves lung health in Mexican women
Women in Central Mexico who used a vented stove instead of the traditional indoor open fire, experienced improved respiratory health on par with a pack-a-day smoker kicking the habit, according to a recent study.
TECNALIA presents innovative mobile robots which are autonomous and polyvalent
TECNALIA Technological Corporation has introduced innovative robots at Euskotren's station in Atxuri (Bilbao) and which are mobile, multifunctional, collaborative, autonomous and polyvalent, suitable for a wide range of work from street cleaning and rubbish collection to accompanying elderly people.
Portable and precise gas sensor could monitor pollution and detect disease
In the air, it is a serious pollutant. In the body, it plays a role in heart rate, blood flow, nerve signals and immune function.
Laser pulses control single electrons in complex molecules
Predatory fish are well aware of the problem: In a swarm of small fish it is hard to isolate prey. A similar situation can be found in the microcosm of atoms and molecules, whose behavior is influenced by "swarms" of electrons.
Carbon monoxide linked to heart problems in elderly
Exposure to carbon monoxide, even at levels well below national limits, is associated with an increased risk of hospitalization for the elderly with heart problems, according to a study published today in Circulation: Journal of the American Heart Association.
More Carbon Monoxide Current Events and Carbon Monoxide News Articles
 |
First Alert CO615 Carbon Monoxide Plug-In Alarm with Battery Backup and Digital Display by First Alert Carbon monoxide (CO) is the leading cause of accidental poisoning deaths in America, yet many people don't know they are suffering from CO poisoning until its too late. Since symptoms of CO poisoning are like the flu, you might not even know you're in danger at first. That's why a carbon monoxide alarm is an excellent way to protect your family. It can detect the CO you can't see, smell or taste in the air. The First Alert CO615 carbon monoxide alarm uses an electrochemical carbon monoxide sensor-the most accurate technology available. Installation is as simple as plugging it in to any wall outlet. Its easy-to-read backlit digital LED display gives you a clear read-out of current CO concentrations in parts per million. The alarm includes a battery back-up giving you peace of mind in a... |
 |
Kidde KN-COPP-B Front Load Battery-Operated Carbon Monoxide Alarm with Digital Display by Kidde Battery Operated Carbon Monoxide Alarm, Includes A Backlight Digital Display Feature, Key Feature Adds An Advanced Level Of Protection, Includes Multiple Mounting Options Allowing Installation On A Wall Or Tabletop, Carefully Designed & Tested To Detect Carbon Monoxide Concentration In A Residential Environment. |
 |
First Alert CO600 Plug In Carbon Monoxide Alarm by First Alert Carbon monoxide (CO) is the leading cause of accidental poisoning deaths in America, yet many people don't know they are suffering from CO poisoning until its too late. Since symptoms of CO poisoning are like the flu, you might not even know you're in danger at first. That's why a carbon monoxide alarm is an excellent way to protect your family. It can detect the CO you can't see, smell or taste in the air. The First Alert CO600 carbon monoxide alarm uses an electrochemical carbon monoxide sensor-the most accurate technology available. Installation is as simple as plugging it in to any wall outlet. The test/silence button both silences a non-threatening alarm and allows you to test the unit's functionality. The unit monitors and re-alarms if carbon monoxide levels persist sounding a... |
 |
First Alert CO400 Battery Powered Carbon Monoxide Alarm by First Alert Carbon monoxide (CO) is the leading cause of accidental poisoning deaths in America, yet many people don't know they are suffering from CO poisoning until its too late. Since symptoms of CO poisoning are like the flu, you might not even know you're in danger at first. That's why a carbon monoxide alarm is an excellent way to protect your family. It can detect the CO you can't see, smell or taste in the air. The First Alert CO400 carbon monoxide alarm uses an electrochemical carbon monoxide sensor-the most accurate technology available. The permanent sensor lasts up to five years. It is powered by two AA replaceable alkaline batteries giving you peace of mind even during power outages. The test/silence button both silences the alarm and allows you to test its functionality. The unit... |
 |
Kidde Nighthawk 900-0089 Carbon Monoxide Alarm by Kidde Protect your family with the worlds most accurate carbon monoxide alarm. The Carbon Monoxide Alarm with display offers the protection and features that you have come to expect from Kidde. This alarm offers the convenience of a large, easy to read digital LCD display, the added protection of battery back-up in case of a power outage and easy to install mounting options. Features: -Large Digital LCD readout displays carbon monoxide level clearly -Easy-to-install mounting options: Place on table or mount on the wall -Works during power outages using 3 AA batteries (included) -Peak level memory recalls the highest danger level detected -No costly sensor replacement needed -Updated digital reading every 15 sec. lets you see if and when levels change -Digital readout from 30-999PPM... |
 |
Kidde KN-COPP-3 Nighthawk Plug-In Carbon Monoxide Alarm with Battery Backup and Digital Display by Kidde This Carbon Monoxide Alarm offers digital display allowing easy viewing of carbon monoxide levels. Its 9V battery back up provides you and your family protection even during power outages. The KN-COPP-3 features a hide-a-way cord that allows for multiple installation possibilities. Digital Display, 9V battery back up, Hide-a-way cord, Test/Reset Button, Loud 85dB Alarm, Low Battery Warning, Easy Installation |
 |
Kidde KN-COSM-IB Hardwire Combination Carbon Monoxide and Smoke Alarm with Battery Backup and Voice Warning, Interconnectable by Kidde Untitled Document .caption { font-family: Verdana, Helvetica neue, Arial, serif; font-size: 10px; font-weight: bold; font-style: italic; } ul.indent { list-style: inside disc; text-indent: 20px; } table.callout { font-family: Verdana, Helvetica, Arial, serif; margin: 10px; width: 250; } td.callout3-c26 { height: 100 percent; background: url('http://g-ecx.images-amazon.com/images/G/01/th/detail-pages/kidde/G/01/th/detail-pages/kidde/c26-callout3.png') repeat-y; border-left: 0px solid #999999; border-right: 1px solid #999999; padding: 10px; width: 250px; } ul.callout { list-style: inside disc; text-indent: -12px; font-size: 12px; line-height: 1.5em; } h5.callout { text-align: center; } img.withlink {border:1px black solid;} a.nodecoration {text-decoration: none} span.style171... |
 |
Kidde KN-COSM-B Battery-Operated Combination Carbon Monoxide and Smoke Alarm with Talking Alarm by Kidde Combination smoke alarm and CO detector is designed with a voice alarm indicator that designates a fire or CO warning. As a reminder, smoke detectors should be installed on every floor in your home in a central location. |
 |
Kidde 900-0234 NightHawk Carbon Monoxide Alarm, Long Life AC Powered with Battery Backup and Digital Display by Kidde The Nighthawk, AC Powered, Plug-In Carbon Monoxide Alarm With Battery Backup, Easy To Install, Provides Reliable Protection Against The Dangers Of Carbon Monoxide, Written Information & Instruction, Operation Easy To Understand, AC/DC Basic Alarm Has A Small Sleek Design That Is Suitable For All Living Areas & Has A 7 Year Limited Warranty. |
 |
First Alert SC05CN Battery Operated Combination Carbon Monoxide/Smoke Alarm by First Alert Carbon monoxide (CO) is the leading cause of accidental poisoning deaths in America, yet many people don't know they are suffering from CO poisoning until its too late. Since symptoms of CO poisoning are like the flu, you might not even know you're in danger at first. That's why a carbon monoxide alarm is an excellent way to protect your family. It can detect the CO you can't see, smell or taste in the air. The First Alert SCO5CN carbon monoxide and smoke alarm uses an electrochemical carbon monoxide sensor-the most accurate technology available. The alarm uses photoelectric smoke sensing technology which is environmentally friendlier and which reduces nuisance alarms, making it ideal for cooking areas. It is also great for sensing slow smoldering fires quickly. The permanent sensors... |
| © 2009 BrightSurf.com |