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Treatment of asthma: Stepping up treatment and also stepping it down
April 10, 2007Asthma symptoms vary greatly among individuals and vary at times with each individual. In this comprehensive study in the April issue of Mayo Clinic Proceedings, researchers address the prevalence and process of step-down therapy as symptoms subside. Of the 397 adults and children studied, 64 percent had at least one change in medication dose during the two years of the study. Most changes were step-up in doses during an asthma flare. Step-down changes were far less common.
Lead author Barbara Yawn., M.D., from the Department of Research at Olmsted Medical Center in Rochester, Minn., comments that "patients indicate it is important to them to take the lowest possible dose of medication to maintain asthma control, suggesting we need to step down therapy when feasible."
This is one of the first studies to address the frequency, type and context of step-up and step-down changes in asthma therapy for children and young adults. The study asserts that asthma care continues to be episodic, with most physician visits occurring at a flare-up. Additional research will help determine the best course of long-term treatment for patients with asthma.
Mayo Clinic
Mayo Clinic
Asthma Current Events and Asthma News RSSFall babies: Born to wheeze?
It is said that timing is everything, and that certainly appears to be true for autumn infants. Children who are born four months before the height of cold and flu season have a greater risk of developing childhood asthma than children born at any other time of year, according to new research.
Hospital visits for respiratory illnesses spiked during Southern California wildfires
Raging wildfires that engulfed Southern California earlier this decade not only destroyed neighborhoods laying in their path, they also caused significant health problems for many who lived outside the fires' reach.
The miseries of allergies just may help prevent some cancers, study finds
There may be a silver -- and healthy -- lining to the miserable cloud of allergy symptoms: Sneezing, coughing, tearing and itching just may help prevent cancer -- particularly colon, skin, bladder, mouth, throat, uterus and cervix, lung and gastrointestinal tract cancer, according to a new Cornell study.
Is ineffective esophageal motility associated with gastropharyngeal reflux disease?
IEM is associated with an increased acid clearance times in the distal esophagus. Gastropharyngeal reflux causes supraesophageal manifestations such as globus, chronic cough, hoarseness, asthma, chronic sinusitis, or other otorhinolaryngologic diseases.
Flu vaccination rates lag for at-risk adolescents
Influenza vaccination rates for adolescents who suffer from asthma and other illnesses are still far too low, according to a recent study.
Tweens and teens double use of diabetes drugs
America's tweens and teens more than doubled their use of type 2 diabetes medications between 2002 and 2005, with girls between 10 and 14 years of age showing a 166 percent increase. One likely cause: Obesity, which is closely associated with type 2 diabetes.
Researchers Apply Systems Biology and Glycomics to Study Human Inflammatory Diseases
An innovative systems biology approach to understanding the carbohydrate structures in cells is leading to new ways to understand how inflammatory illnesses and cardiovascular disease develop in humans. The work was described in two recent publications by University at Buffalo chemical engineers.
NASA-enhanced dust storm predictions to aid health community
NASA satellite data can improve forecasts of dust storms in the American Southwest in ways that can benefit public health managers. Scientists announced the finding as a five-year NASA-funded project nears its conclusion.
In mice, anxiety is linked to immune system
In the first study ever to genetically link the immune system to normal behavior, scientists at Rockefeller and Columbia universities show that mast cells, known as the pharmacologic bombshells of the immune system, directly influence how mice respond to stressful situations.
Green neighborhoods may reduce childhood obesity
Childhood obesity can lead to type 2 diabetes, asthma, hypertension, sleep apnea and emotional distress. Obese children and youth are likely to be obese as adults, experience more cardiovascular disease, high blood pressure and stroke and incur higher healthcare costs.
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