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Rotavirus can spread beyond the intestine
April 17, 2007A new study in PLoS Medicine has shown that children who have rotavirus, a very common cause of diarrhea in children, and who have antigens (protein fragments from the surface of the virus) in their blood, also have infectious virus in their blood. Margaret Conner and colleagues from Baylor College of Medicine, Houston Texas, tested samples obtained from hospitalized children with gastroenteritis and compared them with samples taken from children admitted with bronchiolitis or noninfectious, nonchronic conditions and healthy adults.
Rotavirus antigen was detected in the blood of 51 of 57 of children with rotavirus-positive stools, in 8 of 9 of children without diarrhea but with rotavirus-positive stools, in 2 of 17 children with bronchiolitis of unknown cause without gastroenteritis, and in 5 of 41 children with gastroenteritis but with rotavirus-negative stools. No antigen was found in the blood of any other groups. A further study of 11 children who had antigen in their blood and 9 who did not showed that infectious virus was detected in the blood of all 11 children who were antigen-positive children but in just 2 out of 9 children who were antigen-negative.
The authors conclude that in the children studied most of those infected with rotavirus also had infectious virus in their blood. The presence of virus in the blood appears to be directly related to the presence of antigen in the blood but is independent of the presence of diarrhea. The finding of infectious rotavirus in the blood suggests that the disease is not limited to just the intestine. A related perspective by David Candy discusses the study's findings further.
Public Library of Science
Public Library of Science
Rotavirus Current Events and Rotavirus News RSSScientists link immune system's natural killer cells to infant liver disease
Scientists have linked an overactive response by one of the immune system's key weapons against infection - natural killer, or NK, cells - to the onset of biliary atresia in infants, a disease where blocked bile ducts can cause severe liver damage and death.
New images may improve vaccine design for deadly rotavirus
Howard Hughes Medical Institute researchers are reporting the first detailed molecular snapshots of a deadly gastrointestinal virus as it is caught in the grasp of an immune system molecule with the capacity to destroy it.
Researchers find chink in the armor of viral 'tummy bug'
Researchers at Griffith University's Institute for Glycomics in collaboration with colleagues at the University of Melbourne have moved a step closer to identifying a broad spectrum treatment for the dreaded 'viral tummy bug' or rotavirus.
Integrins as receptors give insight into rotavirus and diarrhea
Eleven years ago, Dr. Mary Estes of Baylor College of Medicine and her colleagues discovered the first viral enterotoxin, rotavirus NSP4, a toxic protein that affects the intestines, causing diarrhea.
Tool creates personalized catch-up immunization schedules for missed childhood vaccinations
A new downloadable software tool will help pediatricians, parents and other health care professionals determine how to adjust complex childhood immunization schedules when one or more vaccine doses aren't received at the proper time.
New Clorox disinfectant is EPA registered to kill both known types of MRSA
While MRSA has been an issue in healthcare settings for years, CA-MRSA outbreaks in the community have been on the rise, with the greatest risk in community settings such as fitness clubs, in sports teams, at schools and daycare centers.
IAVI statement on new analysis of STEP large-scale AIDS vaccine trial
The International AIDS Vaccine Initiative (IAVI) issued the following statement from its President and CEO, Dr. Seth Berkley, following the release of the first analysis of the entire study population from a late-stage AIDS vaccine trial, known as the STEP study.
Soy isoflavone may inhibit common gastrointestinal illness in infants
The soy isoflavone genistin--at concentrations present in soy infant formula-- may reduce a baby's susceptibility to rotavirus infections by as much as 74 percent.
Study reveals gaps in vaccine financing for underinsured children
A national survey of state immunization program managers reveals gaps in coverage for the current vaccine financing system, suggesting that many underinsured children may not receive recommended vaccinations, such as for pneumonia and meningitis.
Researchers Develop Criteria to Detect Bone Mass Deficiencies in Children with Chronic Diseases
Pediatricians now have a practical tool to help determine whether children with chronic diseases like Crohn's, juvenile arthritis and anorexia nervosa -- or those undergoing cancer treatment -- are at increased risk for bone mass deficiencies, fracture or osteoporosis as they get older.
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Rotavirus: Methods & Protocols (Methods in Molecular Medicine) by James Gray (Editor), Ulrich Desselberger (Editor) Addenbrooke's Hospital, Cambridge, UK. Collection of established methods for studying the structure, molecular biology, pathogenesis, epidemiology, and prevention in animal models of infection with rotaviruses, a cause of infant morbidity and mortality. Expanded-outline format. DNLM: Rotavirus Laboratory Manuals. |
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Germ Guardian Personal Air Purifier by Guardian Technologies Breathe healthier air wherever you go. Germ Guardian personal air purifier helps push allergens and pollutants away from you by emitting healthy negative ions. Help keep your family healthy the safe, natural way. Fits easily around your neck or in a shirt pocket, to provide a healthier breathing experience. |
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Germ Guardian Dry Heat Nursery Sanitizer by Guardian Technologies Germs can be passed on toys, especially moist soft toys, where a wet environment is the perfect breeding ground for germs. Help stop the spread of germs on toys, pacifiers, bottles and other baby items, with the Germ Guardian Nursery Sanitizer.It effectiv |
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Infectious Disease Tests & Controls, Rotavirus Tests - Viral Infection Tests & Control Sets by SA Scientific These rapid diagnostic tests are designed to facilitate the detection of a variety of viral and bacterial infectious diseases. Three viral infection tests are available: adenovirus, which can detect all 41 known adenovirus strains; rotavirus, which can detect all rotavirus strains; and RSV, which can detect the respiratory syncytial virus. Controls to validate results must be purchased separately. Tests are conducted by adding specimen samples into sample wells and simply reading results, which are available within 15 minutes. The bacterial infection StrepAlert test provides an immunoassay for Strep A. Controls are included with this test. The procedure is conducted with a dipstick and provides results within five minutes. | |
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Rotavirus from Stool Diarrhea Virus Intestinal Photographic Poster Print, 16x12 by Art.com Art.com is the world's largest retailer of art prints, posters, photographs, and framed artwork. With our huge selection of over 400,000 prints, you'll easily find the perfect piece for your home, office, or classroom. Our art is printed on quality paper. When you order framed artwork, the piece is built by our team of in-house professionals. Visit our Amazon store today at www.amazon.com/artdotcom to find Special Offers and search for products based on 'Artist Name' and 'Subject Categories' such as Movie, Music, Vintage, TV, Children, Travel, Kitchen, Museum Art, Animals, Floral, Motivational, and Sports. Art.com is dedicated to providing you with high quality products and service by offering you 100% satisfaction guaranteed. We ship internationally to over 80 countries. Decorate your... |
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Germ Guardian Tabletop Air Purifier by Guardian Technologies To help create a healthier indoor environment use the Germ Guardian Hygia 4.0 Table Top. The Hygia 4.0 offers four stages of air filtration that helps purify the air. It is the perfect air purifier for the home or office. Small and compact, it's great to |
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