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New study: Pycnogenol reduces heart failure
May 17, 2007A study to be published in an upcoming edition of the journal of Cardiovascular Toxicology reveals Pycnogenol natural pine bark extract from the French maritime pine tree, helps prevent damage that high blood pressure causes to the heart. The study demonstrates Pycnogenol counteracts the "wearing out" of the heart, which may aid the five million Americans living with heart failure. Previous studies have shown Pycnogenol supplementation to be associated with improved cardiovascular health, such as cholesterol reduction, blood pressure control and prevention of thrombosis.
In hypertension, the over-worked heart gradually wears out, resulting in the weakening of the heart muscle and increasing of heart chamber volume. This process (known as cardiac remodeling) may eventually cause heart failure when the heart insufficiently supplies the body with oxygenated blood. The study showed that Pycnogenol prevents the heart from getting worn out during hypertension. Cardiac chamber walls showed a significantly higher rate of collagen connective tissues than control groups.
"Alternative treatments such as Pycnogenol are crucial components in the fight against heart disease,"said Dr. Ronald Watson, professor in the Department of Nutritional Sciences at the University of Arizona and a lead researcher of the study. "The effectiveness of Pycnogenol supplementation is a great option for many people who want an alternative to prescription medications such as beta blockers or ACE inhibitors. This new study shows Pycnogenol administers a therapeutic effect to limit the degenerative process in patients predisposed to congestive heart failure, such as the aged."
The study was conducted at the University of Arizona, Tucson. Elderly female mice (18 months old) were randomly divided into four groups: control mice, mice receiving Pycnogenol only, mice receiving L-NAME only (a substance which causes arterial constriction) and mice receiving both Pycnogenol and L-NAME. Pycnogenol and L-NAME were administered in tap water and the study was approved by the Animal Review Committee at the University of Arizona.
One group of hypertensive mice received Pycnogenol in drinking water for four weeks and another group of hypertensive mice was left untreated. After five weeks, the hearts of the latter control group had significantly increased in size as a result of hypertension. In the Pycnogenol treated group, hypertension and heart function parameters resembled those found in healthy control mice with healthy blood pressure.
"This study provides evidence that oral administration of Pycnogenol reversed cardiovascular remodeling induced by L-NAME by blocking nitric oxide production, which leads to hypertension and finally cardiomyopathy,"said Watson.
After a detailed investigation of the heart tissue, Watson found Pycnogenol supplementation to significantly enhance the connective collagen matrix of cardiac tissue. Whereas the chronic hypertension in mice led to a significant loss of connective collagen fibers, Pycnogenol significantly increased the collagen presence, resulting in stronger cardiac chambers.
According to the American Heart Association nearly five million Americans are living with heart failure, and 550,000 new cases are diagnosed each year. The mortality rate for heart failure affects 80 percent of men and 70 percent of women within 12 years of obtaining cardiovascular diseases. According to Watson, cardiac remodeling is considered an important therapeutic target to battle this disease.
Watson presented the new research this month at the SupplySide East Educational Conference and Trade Show in Secaucus, NJ. Previous clinical research shows Pycnogenol to battle coronary heart disease and stroke, high blood cholesterol and hypertension. Research shows Pycnogenol to diminish the major cardiovascular risk factors simultaneously while offering a safe, natural approach.
MWW Group
The study was conducted at the University of Arizona, Tucson. Elderly female mice (18 months old) were randomly divided into four groups: control mice, mice receiving Pycnogenol only, mice receiving L-NAME only (a substance which causes arterial constriction) and mice receiving both Pycnogenol and L-NAME. Pycnogenol and L-NAME were administered in tap water and the study was approved by the Animal Review Committee at the University of Arizona.
One group of hypertensive mice received Pycnogenol in drinking water for four weeks and another group of hypertensive mice was left untreated. After five weeks, the hearts of the latter control group had significantly increased in size as a result of hypertension. In the Pycnogenol treated group, hypertension and heart function parameters resembled those found in healthy control mice with healthy blood pressure.
"This study provides evidence that oral administration of Pycnogenol reversed cardiovascular remodeling induced by L-NAME by blocking nitric oxide production, which leads to hypertension and finally cardiomyopathy,"said Watson.
After a detailed investigation of the heart tissue, Watson found Pycnogenol supplementation to significantly enhance the connective collagen matrix of cardiac tissue. Whereas the chronic hypertension in mice led to a significant loss of connective collagen fibers, Pycnogenol significantly increased the collagen presence, resulting in stronger cardiac chambers.
According to the American Heart Association nearly five million Americans are living with heart failure, and 550,000 new cases are diagnosed each year. The mortality rate for heart failure affects 80 percent of men and 70 percent of women within 12 years of obtaining cardiovascular diseases. According to Watson, cardiac remodeling is considered an important therapeutic target to battle this disease.
Watson presented the new research this month at the SupplySide East Educational Conference and Trade Show in Secaucus, NJ. Previous clinical research shows Pycnogenol to battle coronary heart disease and stroke, high blood cholesterol and hypertension. Research shows Pycnogenol to diminish the major cardiovascular risk factors simultaneously while offering a safe, natural approach.
MWW Group
Pycnogenol Current Events and Pycnogenol News RSSStudy demonstrates the anti-inflammatory properties of pine bark extract
A recent study published in International Immunopharmacology, reveals why Pycnogenol (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, is effective for reducing inflammation and soothing pain associated with various health problems.
Pine bark reduces inflammatory marker CRP in osteoarthritis
Osteoarthritis (OA), a type of arthritis caused by the breakdown and loss of cartilage, affects more than 20 million Americans.
Study shows pine bark reduces jetlag
A new study published in the journal of Minerva Cardioangiologica reveals Pycnogenol, pine bark extract from the French maritime pine tree, reduces jetlag in passengers by nearly 50 percent.
Study shows pine bark naturally reduces knee osteoarthritis
According to the Center for Disease Control (CDC), osteoarthritis, the most common type of arthritis, is on the rise. A new study published in the August journal of Phytotherapy Research, reveals Pycnogenol, bark extract from the French maritime pine tree, reduced overall knee osteoarthritis (OA) symptoms by 20.9 percent and lowered pain by 40.3 percent.
Study shows pine bark naturally reduces cardiovascular risk factors in diabetics
A new study published in the May 2008 (volume 8, issue 25) edition of the journal of Nutrition Research shows Pycnogenol (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, reduces blood sugar in type II diabetes patients, allows people to lower their antihypertensive medication and improves cardiovascular disease (CVD) risk factors.
Study shows pine bark naturally reduces osteoarthritis
More than 20 million Americans suffer from osteoarthritis, with half a million Americans having a total joint replacement each year.
New research accepted for publication in the Journal of Psychopharmacology, demonstrates Pycnogenol, (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, improves the memory of senior citizens.
The study results revealed Pycnogenol improved both numerical working memory as well as spatial working memory using a computerized testing system. The research was presented last week at the Oxygen Club of California 2008 World Congress on Oxidants and Antioxidants in Biology in Santa Barbara, CA.
Horphag's Prelox provides over-the-counter solution
For couples worldwide, erectile dysfunction (ED) is one of the leading contributors to a man's inability to perform. As millions of men in America each year look for a solution, many seek alternative treatments to prescription medications and surgery that may have dangerous side effects.
New study: pine bark extract boosts nitric oxide production
A study to be published in the October edition of Hypertension Research reveals Pycnogenol, (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, helps individuals by enhancing healthy nitric oxide (NO) production which leads to an increase in blood flow and oxygen supply to muscles.
New study: Pine bark extract reduces ADHD symptoms in children
Attention Deficit Hyperactivity Disorder (ADHD) is a prevailing issue in the United States, with millions of children getting diagnosed every year. A new study reveals that Pycnogenol, (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, reduces ADHD in children.
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Source Naturals Pycnogenol, 50mg, Tablets, 120 tablets by Source Naturals Dietary supplement. Proanthocyanidins complex. Pycnogenol is a natural plant product made from the bark of the European coastal pine, Pinus maritima. Pycnogenol is rich in proanthocyanidins, a special class of water-soluble antioxidant flavonoids which are excellent free radical scavengers. Proanthocyanidins are believed to play an important role in maintaining good health. (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease). |
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TwinLabs Pycnogenol Capsules, 50 Mg, 60-Count Bottle by Twinlab Dietary supplement. Patented natural antioxidant standardized pine bark extract. Well tolerated by most highly allergic individuals. No corn, soy, yeast, milk or egg products. No added sugars, salt (sodium), preservatives or tablet binders and coatings. This product is manufactured at our own state of the art facilities with stringent quality control assuring correct potencies and outstanding product freshness. It is packaged in a glass bottle for maximum stability and quality. |
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Source Naturals Pycnogenol 100mg, 60 tablets by Source Naturals Dietary supplement. Proanthocyanidin complex. Pycnogenol is a natural plant product made from the bark of the European coastal pine, Pinus martima. Pycnogenol is rich in proanthocyanidins, a special class of water-soluble antioxidant flavonoids, which are excellent free radical scavengers. Proanthocyanidins are believed to play an important role in maintaining good health (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease). Suitable for vegetarians and Hypoallergenic: Contains no yeast, dairy, egg, corn, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance. |
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Pycnogenol 100mg 30 Caps by Swanson Ultra Put the antioxidant power of pine to work for you with Pycnogenol! This natural extract from the bark of the French maritime pine tree contains some of the most powerful antioxidant flavonoids ever discovered, making it a great source of free-radical protection for collagen structures in the blood vessels, skin, and joint tissues. Our convenient capsules deliver an ultra-potent 100 mg for high-powered antioxidant protection. |
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Source Naturals Pycnogenol Complex, 120 tablets by Source Naturals Dietary supplement. Antioxidant formula rich in flavonoids, proanthocyanidins & Vitamin C. Pycnogenol Complex combines pycnogenol and proanthodyn (grape seed extract), two potent antioxidants, with eight other plantioxidants (plant-derived antioxidants) to create a natural, power-packed antioxidant supplement. Magnesium ascorbate, a non-acidic form of Vitamin C, adds to the antioxidant activity. (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease). |
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Nature's Purest Pine Bark Extract 100 mg /120 caps by Nature's Purest PINE BARK EXTRACT 90%, is a term describing oligomeric proanthocyanidins (OPC), a natural substance derived from the bark of certain pine trees. Studies in the test tube have shown PINE BARK EXTRACT (OPC) to be 50 times more potent than Vitamin E as an antioxidant, and 20 times stronger than Vitamin C. Pine Bark Extract is able to cross the blood barrier of the brain to provide extra protection against free radicals in the nervous system and circulatory system. There is also evidence that Pine Bark Extract provides extra protection for collagen. Pine Bark Extract also frees up Vitamin C to perform its many other important functions.* |
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Natrol Pycnogenol, 50mg Capsules - 60 ea by Natrol Please note: Due to product improvements, the image shown may temporarily appear different from the product received. Beneficial Antioxidant Properties Standardized Pine Bark ExtractPycnogenol® is a natural plant extract made from the bark of Pinus Maritima.Natrol Pycogenol ® contains proanthocyandins, powerful compounds that act as antioxidant, free-radical scavengers.* No yeast, wheat, corn, milk, egg, soy, glutens, artificial colors or flavors, added sugar, starch or preservatives. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Made in USA +Pycnogenol® is a brand of Pine Bark Standardized Extract and a registered trademark of... |
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Now Foods Pycnogenol 30mg, 150 Capsules by NOW Pycnogenol is a concentrated natural extract from the bark of pine trees that grows in this 4,000 square mile forest. These pine trees contain concentrated levels of unique flavonoid compounds that support the body's ability to neutralize free radicals. Free radicals (reactive molecules) can inhibit immune functions and expedite the aging process. * Picture may be of different size or flavor |
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Schiff Pycnogenol, 50 mg, Capsules, 30 capsules (Pack of 2) by Schiff Pycnogenol contains antioxidants isolated by a patented method from French Maritime Pine Bark (Pinus Maritimus). Pycnogenol supports healthy, cardiovascular function by protecting blood vessel lining (endothelial) cells from damage by free radicals. This |
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Pycnogenol 50 mg 50 Caps by Swanson Premium Brand Protect your body against free-radical damage with the natural flavonoid power of Pycnogenol! Derived from the bark of the French maritime pine, Pycnogenol is a water-soluble antioxidant flavonoid extract with highly bioavailable procyanidins, catechins, taxifolins and a wide spectrum of phenolic acids. By providing an optimal combination of these valuable flavonoids in a single, concentrated supplement, Pycnogenol helps the body combat environmental stress while protecting vital collagen structures in the blood vessels, skin and joint tissues against the harmful effects of free radicals. |
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