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Growth factors and environment combine to increase brain maturation
May 30, 2007A new study showing that growth factors and the environment combine to increase brain maturation appears in the May 30th issue of the online, open-access journal PLoS ONE. The study was conducted by Francesca Ciucci, Elena Putignano, Laura Baroncelli, Silvia Landi, Nicoletta Berardi and Lamberto Maffei, based at the Neurobiology Laboratory of Scuola Normale Superiore in Pisa.
Professor Maffei's research group is known for studies on the development and plasticity of the brain. Recent studies by this group have demonstrated that rodents' brains are sensitive to the influences of the environment and in particular that maturation of the visual system is accelerated in an enriched environment, where animals can explore new objects, engage in physical exercise and play. The aim of this research was to clarify the molecular mechanisms that control this phenomenon.
Specifically, in this study a molecular factor, called Insulin-like growth factor I (IGF-I), has been found to be capable of mediating the accelerated maturation of cortical development produced by enriched environment. The present work suggests that IGF-1 action in mediating the effects produced by environmental enrichment on visual system could be exerted through an accelerated maturation of inhibitory circuitry, the modulation of which has already been involved in cortical plasticity. IGF-I could influence the expression of other neurotrophins like NGF and BDNF, important for visual system plasticity. New studies could lead to a better understanding of the relationship between these molecules in the modulation of brain plasticity.
Public Library of Science
Public Library of Science
Brain Maturation Current Events and Brain Maturation News RSSSurprising results in teen study: adolescent risky behavior may signal mature brain
A new study using brain imaging to study teen behavior indicates that adolescents who engage in dangerous activities have frontal white matter tracts that are more adult in form than their more conservative peers.
Autism Consortium members publish in PNAS: Mechanism, treatment for Rett syndrome -- top cause autism girls
The Autism Consortium, an innovative research, clinical and family collaboration dedicated to radically accelerating research and enhancing clinical care for autism spectrum disorders (ASDs), announced today that several Consortium members published a paper with significance for clinical trials in autism in the Proceedings of the National Academy of Sciences.
Misery is not Miserly: New Study Finds Why Even Momentary Sadness Increases Spending
In a new study that links contemporary science with the classic philosophy of William James, a research team finds that people feeling sad and self-focused spend more money to acquire the same commodities than those in a neutral emotional state.
After scrutiny, preemie lung treatments turn out to be safe, effective
Preemies between 28 and 32 weeks are not harmed by a treatment no longer used to help their lungs mature before birth, according to findings of a study in this month's Pediatrics.
Brain wave changes in adolescence signal reorganization of the brain
Brain wave changes in adolescence are related to age, not sexual maturation, and may be associated with one of the brain's major reorganization projects: synaptic pruning, a new study finds.
Insights into activity-dependent neuronal growth through RSRF-supported research
Brain-derived neurotrophic factor (BDNF) has been a subject of keen interest in neuroscientific circles for several years, turning up in studies of conditions ranging from central hypoventilation syndrome to obsessive-compulsive disorder, depression, bipolar disorder and schizophrenia - a range of disorders uncannily parallel to those produced by mutations in the "Rett gene," MeCP2.
Womb needed for proper brain development
The brains of babies born very prematurely do not develop as well as those who are carried to full-term, according to new research presented today at the annual meeting of the Society for Neuroscience in Washington, D.C.
More Brain Maturation Current Events and Brain Maturation News Articles
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Growth and Maturation of the Brain. Progress in Brain Research Volume 4 by Dominick P. & Schade, J. P., eds Purpura (Author) | |
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Positive youth cultures and the developing brain: the maturation of the adolescent brain requires opportunities to interact in group situations which facilitate ... article from: Reclaiming Children and Youth by Erik K. Laursen (Author) This digital document is an article from Reclaiming Children and Youth, published by Reclaiming Children and Youth on June 22, 2009. The length of the article is 2344 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available immediately after purchase. You can view it with any web browser. Citation Details Title: Positive youth cultures and the developing brain: the maturation of the adolescent brain requires opportunities to interact in group situations which facilitate concern for others, problem solving, and responsible behavior. The purposeful design of positive youth cultures supports the brain's development and prepares youth for participation in a democratic society.(Report) Author: Erik K.... | |
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Experimental Studies on the Significance of Active (c.q. REM)-Sleep for Maturation of Brain and Behavior in the Rat by Majid Mirmiran (Author) | |
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Experimental Studies on the Significance of Active (c.q. REM)-Sleep for Maturation of Brain and Behavior in the Rat by Majid Mirmiran (Author) | |
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Brain Maturation and Cognitive Development: Comparative and Cross-Cultural Perspectives (Foundations of Human Behaviour) by Kathleen Gibson (Editor), Anne Petersen (Editor) |
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Mapping brain maturation and cognitive development during adolescence [An article from: Trends in Cognitive Sciences] by T. Paus (Author) This digital document is a journal article from Trends in Cognitive Sciences, published by Elsevier in 2005. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser. Description: Non-invasive mapping of brain structure and function with magnetic resonance imaging (MRI) has opened up unprecedented opportunities for studying the neural substrates underlying cognitive development. There is an emerging consensus of a continuous increase throughout adolescence in the volume of white matter, both global and local. There is less agreement on the meaning of asynchronous age-related decreases in the volume of grey matter in different cortical regions; these might equally represent loss... |
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Growth and Maturation of the Brain, Volume 4 (Progress in Brain Research) by Author Unknown (Editor) |
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Methodological approaches to the study of brain maturation and its abnormalities: summary report (NICHD-Mental retardation research centers series) by Dominick P. et al, editors. PURPURA (Author) | |
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Sex-specific Development of the Human Brain: normal and deviant maturation of anatomy and attentional functions by Susanne Neufang (Author) With the emergence of non-invasive methods like magnetic resonance imaging (MRI) and functional MRI (fMRI), there is growing evidence of maturational changes in both neuro-anatomical structures and neural activation patterns. Developmental changes have been shown to last until adolescence. In study 1, we examined the impact of steroids on the developing brain and found that amygdala and hippocampal as well as parietal volumes were associated with circulating testosterone levels. In the studies 2 to 5 we adressed differences in brain activation patterns of attention between children and adults, where children were either normally developing children or children with ADHD. We found differences in the developmental trajectories in the fronto-striatal pathway between children... |
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Neurobiological Aspects of Maturation and Aging. Progress in Brain Research Volume 40 by D[onald] H[erbert] (born 1921), ed Ford (Author) |
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